FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080237199> ?p ?o ?g. }

• W2080237199 endingPage "20" @default.
• W2080237199 startingPage "7" @default.
• W2080237199 abstract "In many studies of the mammalian brain, subjective assessments of connectivity patterns and connection strengths have been used to subdivide the cortex into separate but linked areas and to make deductions about the flow of information through the cortical network. Here we describe the results of applying statistical analyses to quantitative corticocortical connection data, and the conclusions that can be drawn from such quantitative approaches. Injections of the tracer WGA-HRP were made into different visual areas either side of the middle suprasylvian sulcus (MSS) in 11 adult cats. Retrogradely labelled cells produced by these injections were counted in selected coronal sections taken at regularly spaced intervals (1 mm) through the entire visual cortex, and their cumulative sums and relative proportions in each of 16 recognized visual cortical areas were computed. The surface dimensions of these areas were measured in each cat, from contour lines made on enlarged drawings of the same sections. A total of 116,149 labelled neurons were assigned to all visual cortical areas in the 11 cats, with 5212 others excluded because of their uncertain location. The distribution of relative connection strengths, that is, the percentage of labelled cells per cortical area, was evaluated using non-parametric cluster analyses and Monte Carlo simulation, and relationships between connection strength and area size were examined by linear regression. The absolute size of each visual cortical area was uniform across individual cats, whereas the strengths of connections between the same area pairs were extremely variable for injections in different animals. The overall distribution of labelling strengths for corticocortical connections was continuous and monotonic, rather than inherently clustered, with the highest frequencies presented by the absent (zero density) and the very-low-density connections. These two categories could not, on analytical grounds, be separated from each other. Thus it seems that any subjective description of corticocortical connectivity strengths by ordinal classes (such as 'absent', 'weak', 'moderate' or 'strong') imposes a categorization on the data, rather than recognizes a structure inherent in the data themselves. Despite the great variability of connections, similarities in the distribution profiles for the relative strengths of labelled cells in all areas could be used to identify clusters of different injection sites in the MSS. This supported the conclusion that there are four connectionally distinct subdivisions of this cortex, corresponding to areas 21a, PMLS and AMLS (in the medial bank) and to area PLLS (in the lateral bank). Even for tracer deposits in the same cortical subdivision, however, the strength of connections projecting to the site from other cortical areas varied greatly across injection in different individual animals. We further demonstrated that, on average, the strength of connections originating from any given cortical area was positively and linearly correlated with the size of its surface dimensions. When analysed by specific injection site location, however, this relationship was shown to hold for the individual connections to the medial bank MSS areas, but not for connections leading to the lateral bank area. The data suggest that connectivity of the cat's visual cortex possesses a number of uniform global features, which are locally organized in such a way as to give each cortical area unique characteristics." @default.
• W2080237199 created "2016-06-24" @default.
• W2080237199 creator A5045659246 @default.
• W2080237199 creator A5073687980 @default.
• W2080237199 date "2000-01-29" @default.
• W2080237199 modified "2023-10-10" @default.
• W2080237199 title "Uniformity, specificity and variability of corticocortical connectivity" @default.
• W2080237199 cites W1560129441 @default.
• W2080237199 cites W1603661052 @default.
• W2080237199 cites W1975014018 @default.
• W2080237199 cites W1975700187 @default.
• W2080237199 cites W1982150266 @default.
• W2080237199 cites W1988711299 @default.
• W2080237199 cites W1995261715 @default.
• W2080237199 cites W2000857380 @default.
• W2080237199 cites W2005533012 @default.
• W2080237199 cites W2005598371 @default.
• W2080237199 cites W2008407507 @default.
• W2080237199 cites W2009457661 @default.
• W2080237199 cites W2009696225 @default.
• W2080237199 cites W2011017455 @default.
• W2080237199 cites W2016792902 @default.
• W2080237199 cites W2020427957 @default.
• W2080237199 cites W2023413114 @default.
• W2080237199 cites W2024806220 @default.
• W2080237199 cites W2026256491 @default.
• W2080237199 cites W2033491974 @default.
• W2080237199 cites W2034469137 @default.
• W2080237199 cites W2053044392 @default.
• W2080237199 cites W2053711435 @default.
• W2080237199 cites W2054436393 @default.
• W2080237199 cites W2059227497 @default.
• W2080237199 cites W2059421850 @default.
• W2080237199 cites W2064440086 @default.
• W2080237199 cites W2064694807 @default.
• W2080237199 cites W2066511633 @default.
• W2080237199 cites W2076185004 @default.
• W2080237199 cites W2080579153 @default.
• W2080237199 cites W2087438797 @default.
• W2080237199 cites W2106306931 @default.
• W2080237199 cites W2120006789 @default.
• W2080237199 cites W2127813444 @default.
• W2080237199 cites W2138996400 @default.
• W2080237199 cites W2156616849 @default.
• W2080237199 cites W2321071450 @default.
• W2080237199 cites W2395877712 @default.
• W2080237199 cites W2405002066 @default.
• W2080237199 cites W2411271314 @default.
• W2080237199 doi "https://doi.org/10.1098/rstb.2000.0546" @default.
• W2080237199 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1692717" @default.
• W2080237199 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10703041" @default.
• W2080237199 hasPublicationYear "2000" @default.
• W2080237199 type Work @default.
• W2080237199 sameAs 2080237199 @default.
• W2080237199 citedByCount "41" @default.
• W2080237199 countsByYear W20802371992012 @default.
• W2080237199 countsByYear W20802371992013 @default.
• W2080237199 countsByYear W20802371992014 @default.
• W2080237199 countsByYear W20802371992016 @default.
• W2080237199 countsByYear W20802371992017 @default.
• W2080237199 countsByYear W20802371992018 @default.
• W2080237199 countsByYear W20802371992019 @default.
• W2080237199 countsByYear W20802371992020 @default.
• W2080237199 crossrefType "journal-article" @default.
• W2080237199 hasAuthorship W2080237199A5045659246 @default.
• W2080237199 hasAuthorship W2080237199A5073687980 @default.
• W2080237199 hasBestOaLocation W20802371992 @default.
• W2080237199 hasConcept C105702510 @default.
• W2080237199 hasConcept C13355873 @default.
• W2080237199 hasConcept C13483470 @default.
• W2080237199 hasConcept C149635348 @default.
• W2080237199 hasConcept C169760540 @default.
• W2080237199 hasConcept C2524010 @default.
• W2080237199 hasConcept C26760741 @default.
• W2080237199 hasConcept C2777132076 @default.
• W2080237199 hasConcept C2777348757 @default.
• W2080237199 hasConcept C2778355574 @default.
• W2080237199 hasConcept C2779345533 @default.
• W2080237199 hasConcept C2779904517 @default.
• W2080237199 hasConcept C2779920484 @default.
• W2080237199 hasConcept C2780723820 @default.
• W2080237199 hasConcept C2993054123 @default.
• W2080237199 hasConcept C33923547 @default.
• W2080237199 hasConcept C41008148 @default.
• W2080237199 hasConcept C86803240 @default.
• W2080237199 hasConceptScore W2080237199C105702510 @default.
• W2080237199 hasConceptScore W2080237199C13355873 @default.
• W2080237199 hasConceptScore W2080237199C13483470 @default.
• W2080237199 hasConceptScore W2080237199C149635348 @default.
• W2080237199 hasConceptScore W2080237199C169760540 @default.
• W2080237199 hasConceptScore W2080237199C2524010 @default.
• W2080237199 hasConceptScore W2080237199C26760741 @default.
• W2080237199 hasConceptScore W2080237199C2777132076 @default.
• W2080237199 hasConceptScore W2080237199C2777348757 @default.
• W2080237199 hasConceptScore W2080237199C2778355574 @default.
• W2080237199 hasConceptScore W2080237199C2779345533 @default.
• W2080237199 hasConceptScore W2080237199C2779904517 @default.
• W2080237199 hasConceptScore W2080237199C2779920484 @default.

• next