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- W2080239871 abstract "The enzyme 11β-hydroxysteroid dehydrogenase, by converting cortisol and corticosterone to their receptor-inactive 11-keto metabolites cortisone and 11-dehydrocorticosterone, appears crucial to the aldosterone-selectivity of renal mineralocorticoid receptors. Levels of enzyme activity in the rat kidney, measured by conversion of cortisol to cortisone, are unaltered by changes in adrenal or thyroid status, or by castration in either sex; in contrast, oestrogen administration increases enzyme activity in male rats." @default.
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- W2080239871 date "1991-02-01" @default.
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- W2080239871 title "Renal 11β-hydroxysteroid dehydrogenase activity: Effects of age, sex and altered hormonal status" @default.
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- W2080239871 doi "https://doi.org/10.1016/0960-0760(91)90135-r" @default.
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