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• W2080249364 abstract "Clostridum difficile—associated disease (CDAD) is the leading cause of infectious diarrhea and is associated with considerable morbidity and mortality. The incidence is estimated to range from 3.4 to 8.4 cases per 1000 hospital admissions, and it has become a growing problem at many institutions. Treatment options for CDAD are limited due to a paucity of new pharmacologic agents and studies examining other potential treatments. Historically oral metronidazole and oral vancomycin have been used as first-line agents in the treating CDAD, however recent reports of treatment failure and recurrence with these agents have surfaced. These reports illustrate a need for novel pharmacologic agents and a thorough review of currently available agents that may have activity against C difficile. Available data on the treatment of CDAD were extracted and reviewed to outline the appropriate management of CDAD." @default.
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• W2080249364 date "2007-08-01" @default.
• W2080249364 modified "2023-10-17" @default.
• W2080249364 title "Clostridium difficile—Associated Diarrhea, an Emerging Epidemic: Therapeutic Options" @default.
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• W2080249364 doi "https://doi.org/10.1177/0897190007302892" @default.
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