FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080251505> ?p ?o ?g. }

• W2080251505 endingPage "3625" @default.
• W2080251505 startingPage "3617" @default.
• W2080251505 abstract "Rats subjected to early postnatal food restriction (FR) show persistent changes in energy balance. The hypothalamus plays a major role in the regulation of energy balance. Therefore, we hypothesized that early postnatal food restriction induces developmental programming of hypothalamic gene expression of neuropeptides involved in this regulation. In the hypothalamus of juvenile and middle-aged rats that were raised in control (10 pups) or FR litters (20 pups), gene expression was investigated for neuropeptide Y (NPY), agouti-related protein (AgRP), proopiomelanocortin (POMC), and cocaine- and amphetamine-regulated transcript (CART) in the arcuate nucleus (ARC); CRH and TRH in the paraventricular nucleus; and melanin-concentrating hormone (MCH) and orexin in the lateral hypothalamic area. Early postnatal FR acutely and persistently reduced body size. Juvenile FR rats had significantly reduced CART gene expression and increased MCH expression. In middle-aged FR rats, POMC and CART mRNA levels were significantly reduced. The ratio between expression of the ARC orexigenic peptides (NPY and AgRP) and anorexigenic peptides (POMC and CART) was increased in juvenile, but not in middle-aged, FR rats. These results suggest that in neonatal rats, FR already triggers the ARC, and to a lesser extent the lateral hypothalamic area, but not the paraventricular nucleus, to increase expression of orexigenic relative to anorexigenic peptides. In addition, with enduring small body size and normalized hypothalamic gene expression, the adult FR rats appeared to have accepted this smaller body size as normal. This suggests that the body weight set-point was differently programmed in animals with early postnatal FR." @default.
• W2080251505 created "2016-06-24" @default.
• W2080251505 creator A5012988627 @default.
• W2080251505 creator A5033044038 @default.
• W2080251505 creator A5035433879 @default.
• W2080251505 creator A5058483451 @default.
• W2080251505 date "2008-03-27" @default.
• W2080251505 modified "2023-10-18" @default.
• W2080251505 title "Hypothalamic Neuropeptide Expression of Juvenile and Middle-Aged Rats after Early Postnatal Food Restriction" @default.
• W2080251505 cites W1514751206 @default.
• W2080251505 cites W1561443084 @default.
• W2080251505 cites W1567578889 @default.
• W2080251505 cites W1572169004 @default.
• W2080251505 cites W1957164551 @default.
• W2080251505 cites W1964145972 @default.
• W2080251505 cites W1964639026 @default.
• W2080251505 cites W1964819028 @default.
• W2080251505 cites W1964826900 @default.
• W2080251505 cites W1971522193 @default.
• W2080251505 cites W1972318216 @default.
• W2080251505 cites W1975089308 @default.
• W2080251505 cites W1976769232 @default.
• W2080251505 cites W1979578727 @default.
• W2080251505 cites W1980604875 @default.
• W2080251505 cites W1982034861 @default.
• W2080251505 cites W1988106824 @default.
• W2080251505 cites W1988149499 @default.
• W2080251505 cites W1991770461 @default.
• W2080251505 cites W1994360459 @default.
• W2080251505 cites W1999557310 @default.
• W2080251505 cites W1999989426 @default.
• W2080251505 cites W2000448219 @default.
• W2080251505 cites W2001095683 @default.
• W2080251505 cites W2002763203 @default.
• W2080251505 cites W2008081158 @default.
• W2080251505 cites W2008870929 @default.
• W2080251505 cites W2011365147 @default.
• W2080251505 cites W2013679503 @default.
• W2080251505 cites W2018461711 @default.
• W2080251505 cites W2021382068 @default.
• W2080251505 cites W2021471819 @default.
• W2080251505 cites W2024116770 @default.
• W2080251505 cites W2024923637 @default.
• W2080251505 cites W2026086063 @default.
• W2080251505 cites W2028907433 @default.
• W2080251505 cites W2030436882 @default.
• W2080251505 cites W2031087122 @default.
• W2080251505 cites W2036160136 @default.
• W2080251505 cites W2036659686 @default.
• W2080251505 cites W2037951352 @default.
• W2080251505 cites W2040324075 @default.
• W2080251505 cites W2043525975 @default.
• W2080251505 cites W2044424213 @default.
• W2080251505 cites W2046629103 @default.
• W2080251505 cites W2051370124 @default.
• W2080251505 cites W2051391040 @default.
• W2080251505 cites W2056191123 @default.
• W2080251505 cites W2060251751 @default.
• W2080251505 cites W2060992511 @default.
• W2080251505 cites W2081573872 @default.
• W2080251505 cites W2089427676 @default.
• W2080251505 cites W2092192319 @default.
• W2080251505 cites W2102771089 @default.
• W2080251505 cites W2110490571 @default.
• W2080251505 cites W2118345860 @default.
• W2080251505 cites W2125408269 @default.
• W2080251505 cites W2125510262 @default.
• W2080251505 cites W2126181705 @default.
• W2080251505 cites W2127124396 @default.
• W2080251505 cites W2132858654 @default.
• W2080251505 cites W2138572940 @default.
• W2080251505 cites W2138850858 @default.
• W2080251505 cites W2140368520 @default.
• W2080251505 cites W2142847536 @default.
• W2080251505 cites W2159178030 @default.
• W2080251505 cites W2172065946 @default.
• W2080251505 cites W2219578023 @default.
• W2080251505 cites W4231924994 @default.
• W2080251505 doi "https://doi.org/10.1210/en.2007-1388" @default.
• W2080251505 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18372335" @default.
• W2080251505 hasPublicationYear "2008" @default.
• W2080251505 type Work @default.
• W2080251505 sameAs 2080251505 @default.
• W2080251505 citedByCount "36" @default.
• W2080251505 countsByYear W20802515052012 @default.
• W2080251505 countsByYear W20802515052013 @default.
• W2080251505 countsByYear W20802515052014 @default.
• W2080251505 countsByYear W20802515052015 @default.
• W2080251505 countsByYear W20802515052016 @default.
• W2080251505 countsByYear W20802515052017 @default.
• W2080251505 countsByYear W20802515052018 @default.
• W2080251505 countsByYear W20802515052021 @default.
• W2080251505 countsByYear W20802515052023 @default.
• W2080251505 crossrefType "journal-article" @default.
• W2080251505 hasAuthorship W2080251505A5012988627 @default.
• W2080251505 hasAuthorship W2080251505A5033044038 @default.
• W2080251505 hasAuthorship W2080251505A5035433879 @default.
• W2080251505 hasAuthorship W2080251505A5058483451 @default.

• next