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- W2080259621 abstract "Abstract The sensitivity of the superior cervical ganglion (SCG) tissue in the cat to activation by infusion of its normal cholinergic agonist acetylcholine (ACh+) has been compared for animal preparations breathing normal air and those breathing helium-oxygen ( 80% 20% ) at 1 atm. The ganglionic response to infusion of a 1.0 × 10−3 m bolus of ACh+ solution delivered intra-arterially to SCG tissue is approximately 15% less in HeO2 breathing atmospheres than in N2O2. The response decay curves with increasing exposure time for the cat preparation in either breathing atmosphere are linear, and yield net decreases of 10–15% of control amplitudes over the course of 2 hr. The observed effect of 0.80 atm of He, relative to N2, in partial desensitization of cholinergic response at the SCG, is discussed in terms of possible mechanisms of interaction of He with tissue receptor components." @default.
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- W2080259621 date "1976-11-01" @default.
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- W2080259621 title "Helium depression of cholinergic sensitivity in the cat superior cervical ganglion tissue" @default.
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- W2080259621 doi "https://doi.org/10.1016/0041-008x(76)90147-2" @default.
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