FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080262079> ?p ?o ?g. }

• W2080262079 endingPage "149" @default.
• W2080262079 startingPage "145" @default.
• W2080262079 abstract "B-cell chronic lymphocytic leukemia (B-CLL) is the most common leukemia of adults in Western countries. The most frequent recurring chromosomal aberrations identified in B-CLL patients are trisomy 12 and deletions of 13q, 17p, and 11q. Cases with deletions of 11q and 17p have a poor prognosis, whereas cases with deletions in 13q have a favorable prognosis. It was previously shown that CLL patients with trisomy 12 and del(13)(q14) have a higher rate of asynchronous replication of normal structural genes when compared to those with normal karyotypes. We studied the replication pattern of the structural locus 21q22 and the imprinted gene SNRPN and its telomere (15qter) and the random aneuploidy of chromosomes 9 and 18 in CLL patients with trisomy 12 and deletions of 11q and 17p, and compared the results to those of CLL patients without these aberrations and to healthy controls. Random aneuploidy rate was higher in the group of patients with trisomy 12 as compared to all other groups. The replication pattern with higher asynchronous pattern was found in both aberration groups compared to the CLL patients without the aberrations and to the control group with involvement of 21q22 and 15qter, whereas the highest synchronous group was found in the 2 aberrations CLL patient groups compared to the other groups with the imprinted locus SNRPN. The existence and significance of chromosomal aberrations in CLL have a deleterious effect on the processes of cell cycle and gene replication and may have biological and prognostic implications." @default.
• W2080262079 created "2016-06-24" @default.
• W2080262079 creator A5014023450 @default.
• W2080262079 creator A5021879267 @default.
• W2080262079 creator A5026658735 @default.
• W2080262079 creator A5065592667 @default.
• W2080262079 creator A5070574102 @default.
• W2080262079 creator A5091650686 @default.
• W2080262079 date "2006-06-01" @default.
• W2080262079 modified "2023-09-27" @default.
• W2080262079 title "The influence of different chromosomal aberrations on molecular cytogenetic parameters in chronic lymphocytic leukemia" @default.
• W2080262079 cites W1528443459 @default.
• W2080262079 cites W157252568 @default.
• W2080262079 cites W1898400269 @default.
• W2080262079 cites W1983135350 @default.
• W2080262079 cites W1983461362 @default.
• W2080262079 cites W2010959906 @default.
• W2080262079 cites W2028613137 @default.
• W2080262079 cites W2028639123 @default.
• W2080262079 cites W2029761376 @default.
• W2080262079 cites W2039509112 @default.
• W2080262079 cites W2048159430 @default.
• W2080262079 cites W2053374394 @default.
• W2080262079 cites W2056982584 @default.
• W2080262079 cites W2064589511 @default.
• W2080262079 cites W2072248036 @default.
• W2080262079 cites W2077928458 @default.
• W2080262079 cites W2079194524 @default.
• W2080262079 cites W2081479079 @default.
• W2080262079 cites W2082804553 @default.
• W2080262079 cites W2095544760 @default.
• W2080262079 cites W2107350347 @default.
• W2080262079 cites W2107846106 @default.
• W2080262079 cites W2131036127 @default.
• W2080262079 cites W2163894688 @default.
• W2080262079 cites W2314876309 @default.
• W2080262079 cites W4235228584 @default.
• W2080262079 cites W4242788858 @default.
• W2080262079 cites W4302440252 @default.
• W2080262079 doi "https://doi.org/10.1016/j.cancergencyto.2005.11.019" @default.
• W2080262079 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16737914" @default.
• W2080262079 hasPublicationYear "2006" @default.
• W2080262079 type Work @default.
• W2080262079 sameAs 2080262079 @default.
• W2080262079 citedByCount "12" @default.
• W2080262079 countsByYear W20802620792012 @default.
• W2080262079 countsByYear W20802620792013 @default.
• W2080262079 countsByYear W20802620792015 @default.
• W2080262079 crossrefType "journal-article" @default.
• W2080262079 hasAuthorship W2080262079A5014023450 @default.
• W2080262079 hasAuthorship W2080262079A5021879267 @default.
• W2080262079 hasAuthorship W2080262079A5026658735 @default.
• W2080262079 hasAuthorship W2080262079A5065592667 @default.
• W2080262079 hasAuthorship W2080262079A5070574102 @default.
• W2080262079 hasAuthorship W2080262079A5091650686 @default.
• W2080262079 hasConcept C104317684 @default.
• W2080262079 hasConcept C153911025 @default.
• W2080262079 hasConcept C2776229224 @default.
• W2080262079 hasConcept C2777938653 @default.
• W2080262079 hasConcept C2778461978 @default.
• W2080262079 hasConcept C2779672484 @default.
• W2080262079 hasConcept C30481170 @default.
• W2080262079 hasConcept C502942594 @default.
• W2080262079 hasConcept C53226629 @default.
• W2080262079 hasConcept C54355233 @default.
• W2080262079 hasConcept C84597430 @default.
• W2080262079 hasConcept C86803240 @default.
• W2080262079 hasConceptScore W2080262079C104317684 @default.
• W2080262079 hasConceptScore W2080262079C153911025 @default.
• W2080262079 hasConceptScore W2080262079C2776229224 @default.
• W2080262079 hasConceptScore W2080262079C2777938653 @default.
• W2080262079 hasConceptScore W2080262079C2778461978 @default.
• W2080262079 hasConceptScore W2080262079C2779672484 @default.
• W2080262079 hasConceptScore W2080262079C30481170 @default.
• W2080262079 hasConceptScore W2080262079C502942594 @default.
• W2080262079 hasConceptScore W2080262079C53226629 @default.
• W2080262079 hasConceptScore W2080262079C54355233 @default.
• W2080262079 hasConceptScore W2080262079C84597430 @default.
• W2080262079 hasConceptScore W2080262079C86803240 @default.
• W2080262079 hasIssue "2" @default.
• W2080262079 hasLocation W20802620791 @default.
• W2080262079 hasLocation W20802620792 @default.
• W2080262079 hasOpenAccess W2080262079 @default.
• W2080262079 hasPrimaryLocation W20802620791 @default.
• W2080262079 hasRelatedWork W1866648957 @default.
• W2080262079 hasRelatedWork W1967762412 @default.
• W2080262079 hasRelatedWork W1971993735 @default.
• W2080262079 hasRelatedWork W1975485775 @default.
• W2080262079 hasRelatedWork W2011329410 @default.
• W2080262079 hasRelatedWork W2040772222 @default.
• W2080262079 hasRelatedWork W2078332583 @default.
• W2080262079 hasRelatedWork W2144160254 @default.
• W2080262079 hasRelatedWork W2405504318 @default.
• W2080262079 hasRelatedWork W94237879 @default.
• W2080262079 hasVolume "167" @default.
• W2080262079 isParatext "false" @default.
• W2080262079 isRetracted "false" @default.
• W2080262079 magId "2080262079" @default.

• next