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- W2080266380 abstract "ABSTRACT In 1963 we reported the case of a female, 32 years of age, with Cushing's syndrome due to bilateral adrenocortical hyperplasia, and successfully treated with large doses of ethinyloestradiol and subsequent total bilateral adrenalectomy. A round shadow which had been present in her left lung was still unchanged since first observed in 1956. A tumour consisting of closely packed cells, with partly granulated cytoplasm, and apparently nonmalignant, was removed from this lung in January 1967, 5 years after adrenalectomy. After this operation the pigmentation of the patient's skin was reduced. Six months after the operation, while on 5 mg prednisolone administered daily in the morning, her blood plasma contained ACTH in the lower normal range, and β-MSH was not significantly raised. If the tumour was ACTH producing, and was the cause of her Cushing's syndrome, this might explain the unusual and striking effect of the oestrogen treatment observed before adrenalectomy." @default.
- W2080266380 created "2016-06-24" @default.
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- W2080266380 date "1969-06-01" @default.
- W2080266380 modified "2023-10-14" @default.
- W2080266380 title "OESTROGEN TREATMENT IN CUSHING'S SYNDROME" @default.
- W2080266380 doi "https://doi.org/10.1530/acta.0.0610320" @default.
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