FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080287693> ?p ?o ?g. }

• W2080287693 endingPage "73" @default.
• W2080287693 startingPage "67" @default.
• W2080287693 abstract "Background Aim of the present study was to investigate whether 1,25(OH)(2)D(3) (Vitamin D3) modulates T lymphocyte functions in patients transplanted for hepatitis C virus-related cirrhosis. Methods Sixteen patients and ten healthy subjects were investigated. T lymphocytes were activated in vitro in the presence or absence of Vitamin D3 and then the proliferative response and IFN-γ and TNF-α production were assessed. Results Vitamin D3 potently reduced T-lymphocyte proliferation in a dose-related fashion. Similarly, FACS analysis and ELISA testing demonstrated that Vitamin D3 significantly decreased the response frequency and the response intensity of IFN-γ and TNF-α production in the whole CD3-positive T lymphocyte population as well as in “naive” CD4+ CD45RA+ and “memory” CD4+ CD45RO+ T lymphocyte subsets. The inhibitory effect of Vitamin D3 on T-cell proliferation and cytokine production was not different between patients and controls. No toxic effects were exerted by Vitamin D3 even at the higher concentration used (10 nM). Finally, no statistically significant correlation was found between 25(OH)D serum levels and the proliferative response or cytokine production of T lymphocytes from transplanted patients. Conclusions This study demonstrates that in patients transplanted for hepatitis C virus-related cirrhosis Vitamin D3 modulates T lymphocyte activation, and provides a rationale for the evaluation of this compound as an immunosuppressive agent in liver-transplanted patients." @default.
• W2080287693 created "2016-06-24" @default.
• W2080287693 creator A5007976736 @default.
• W2080287693 creator A5013591885 @default.
• W2080287693 creator A5024440171 @default.
• W2080287693 creator A5037238211 @default.
• W2080287693 creator A5044277443 @default.
• W2080287693 creator A5050013350 @default.
• W2080287693 creator A5062294081 @default.
• W2080287693 creator A5087654224 @default.
• W2080287693 date "2012-01-01" @default.
• W2080287693 modified "2023-09-23" @default.
• W2080287693 title "Vitamin D3 modulates T lymphocyte responses in hepatitis C virus-infected liver transplant recipients" @default.
• W2080287693 cites W1516068817 @default.
• W2080287693 cites W1620799781 @default.
• W2080287693 cites W1803681061 @default.
• W2080287693 cites W1966996683 @default.
• W2080287693 cites W1971042423 @default.
• W2080287693 cites W1972922050 @default.
• W2080287693 cites W1975876211 @default.
• W2080287693 cites W1987907459 @default.
• W2080287693 cites W1991530706 @default.
• W2080287693 cites W2006066086 @default.
• W2080287693 cites W2007303522 @default.
• W2080287693 cites W2008695308 @default.
• W2080287693 cites W2009710824 @default.
• W2080287693 cites W2024058529 @default.
• W2080287693 cites W2039709829 @default.
• W2080287693 cites W2049280452 @default.
• W2080287693 cites W2054647786 @default.
• W2080287693 cites W2054666515 @default.
• W2080287693 cites W2064742753 @default.
• W2080287693 cites W2092867365 @default.
• W2080287693 cites W2095483193 @default.
• W2080287693 cites W2097221830 @default.
• W2080287693 cites W2109524291 @default.
• W2080287693 cites W2115710851 @default.
• W2080287693 cites W2118463883 @default.
• W2080287693 cites W2135878618 @default.
• W2080287693 cites W2138328097 @default.
• W2080287693 cites W2143565640 @default.
• W2080287693 cites W2165422261 @default.
• W2080287693 cites W2321403280 @default.
• W2080287693 cites W42684369 @default.
• W2080287693 doi "https://doi.org/10.1016/j.dld.2011.08.010" @default.
• W2080287693 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21930443" @default.
• W2080287693 hasPublicationYear "2012" @default.
• W2080287693 type Work @default.
• W2080287693 sameAs 2080287693 @default.
• W2080287693 citedByCount "5" @default.
• W2080287693 countsByYear W20802876932014 @default.
• W2080287693 countsByYear W20802876932015 @default.
• W2080287693 countsByYear W20802876932020 @default.
• W2080287693 crossrefType "journal-article" @default.
• W2080287693 hasAuthorship W2080287693A5007976736 @default.
• W2080287693 hasAuthorship W2080287693A5013591885 @default.
• W2080287693 hasAuthorship W2080287693A5024440171 @default.
• W2080287693 hasAuthorship W2080287693A5037238211 @default.
• W2080287693 hasAuthorship W2080287693A5044277443 @default.
• W2080287693 hasAuthorship W2080287693A5050013350 @default.
• W2080287693 hasAuthorship W2080287693A5062294081 @default.
• W2080287693 hasAuthorship W2080287693A5087654224 @default.
• W2080287693 hasConcept C124490489 @default.
• W2080287693 hasConcept C126322002 @default.
• W2080287693 hasConcept C203014093 @default.
• W2080287693 hasConcept C2522874641 @default.
• W2080287693 hasConcept C2776090121 @default.
• W2080287693 hasConcept C2776408679 @default.
• W2080287693 hasConcept C2776455275 @default.
• W2080287693 hasConcept C2776940978 @default.
• W2080287693 hasConcept C2777214474 @default.
• W2080287693 hasConcept C2777761686 @default.
• W2080287693 hasConcept C2778690821 @default.
• W2080287693 hasConcept C2778740727 @default.
• W2080287693 hasConcept C2908647359 @default.
• W2080287693 hasConcept C2992881475 @default.
• W2080287693 hasConcept C71924100 @default.
• W2080287693 hasConcept C8891405 @default.
• W2080287693 hasConcept C99454951 @default.
• W2080287693 hasConceptScore W2080287693C124490489 @default.
• W2080287693 hasConceptScore W2080287693C126322002 @default.
• W2080287693 hasConceptScore W2080287693C203014093 @default.
• W2080287693 hasConceptScore W2080287693C2522874641 @default.
• W2080287693 hasConceptScore W2080287693C2776090121 @default.
• W2080287693 hasConceptScore W2080287693C2776408679 @default.
• W2080287693 hasConceptScore W2080287693C2776455275 @default.
• W2080287693 hasConceptScore W2080287693C2776940978 @default.
• W2080287693 hasConceptScore W2080287693C2777214474 @default.
• W2080287693 hasConceptScore W2080287693C2777761686 @default.
• W2080287693 hasConceptScore W2080287693C2778690821 @default.
• W2080287693 hasConceptScore W2080287693C2778740727 @default.
• W2080287693 hasConceptScore W2080287693C2908647359 @default.
• W2080287693 hasConceptScore W2080287693C2992881475 @default.
• W2080287693 hasConceptScore W2080287693C71924100 @default.
• W2080287693 hasConceptScore W2080287693C8891405 @default.
• W2080287693 hasConceptScore W2080287693C99454951 @default.
• W2080287693 hasIssue "1" @default.
• W2080287693 hasLocation W20802876931 @default.

• next