FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080293143> ?p ?o ?g. }

• W2080293143 abstract "Prostanoids, consisting of the prostaglandins (PGs) and thromboxanes (TXs), exert various actions through activation of their specific receptors. They include the DP, EP, FP, IP, and TP receptors for PGD2, PGE2, PGF2alpha, PGI2, and TXA2, respectively. Moreover, EP receptors are classified into four subtypes, the EP1, EP2, EP3 and EP4 receptors. Using mice lacking prostanoid receptors, we intended to clarify in vivo roles of prostanoids under pathophysiological conditions of the cardiovascular system, which include ischemia-induced cardiac injury, pressure overload-induced cardiac hypertrophy, renovascular hypertension, tachycardia during systemic inflammation and thromboembolism. The results demonstrated that 1) PGI2 plays an important role in attenuating the ischemic injury and the pressure overload-induced hypertrophy of the hearts, and also contributes to the development of renovascular hypertension; 2) PGE2 plays a cardioprotective role against the ischemic injury via both the EP3 and EP4, and also participates in acute thromboembolism via the EP3; and 3) both PGF2alpha and TXA2, which have been produced during systemic inflammation, are responsible for tachycardia." @default.
• W2080293143 created "2016-06-24" @default.
• W2080293143 creator A5009263758 @default.
• W2080293143 creator A5016507067 @default.
• W2080293143 creator A5024624058 @default.
• W2080293143 creator A5058763731 @default.
• W2080293143 creator A5086374156 @default.
• W2080293143 date "2003-01-01" @default.
• W2080293143 modified "2023-10-03" @default.
• W2080293143 title "Pathophysiological roles of the prostanoids in the cardiovascular system: Studies using mice deficient in prostanoid receptors" @default.
• W2080293143 cites W183417552 @default.
• W2080293143 cites W1967845968 @default.
• W2080293143 cites W1969574814 @default.
• W2080293143 cites W1970253641 @default.
• W2080293143 cites W1972202896 @default.
• W2080293143 cites W1984893737 @default.
• W2080293143 cites W2005506628 @default.
• W2080293143 cites W2012007089 @default.
• W2080293143 cites W2014791861 @default.
• W2080293143 cites W2016416373 @default.
• W2080293143 cites W2029259864 @default.
• W2080293143 cites W2030939387 @default.
• W2080293143 cites W2039566216 @default.
• W2080293143 cites W2056345638 @default.
• W2080293143 cites W2061938033 @default.
• W2080293143 cites W2067891203 @default.
• W2080293143 cites W2069528976 @default.
• W2080293143 cites W2085049416 @default.
• W2080293143 cites W2086928528 @default.
• W2080293143 cites W2097691733 @default.
• W2080293143 cites W2110279874 @default.
• W2080293143 cites W2121612337 @default.
• W2080293143 cites W2241152499 @default.
• W2080293143 cites W2258579859 @default.
• W2080293143 cites W2263048471 @default.
• W2080293143 cites W2299579881 @default.
• W2080293143 cites W2414678281 @default.
• W2080293143 cites W2419424642 @default.
• W2080293143 doi "https://doi.org/10.1254/fpj.122.384" @default.
• W2080293143 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14569157" @default.
• W2080293143 hasPublicationYear "2003" @default.
• W2080293143 type Work @default.
• W2080293143 sameAs 2080293143 @default.
• W2080293143 citedByCount "0" @default.
• W2080293143 crossrefType "journal-article" @default.
• W2080293143 hasAuthorship W2080293143A5009263758 @default.
• W2080293143 hasAuthorship W2080293143A5016507067 @default.
• W2080293143 hasAuthorship W2080293143A5024624058 @default.
• W2080293143 hasAuthorship W2080293143A5058763731 @default.
• W2080293143 hasAuthorship W2080293143A5086374156 @default.
• W2080293143 hasBestOaLocation W20802931431 @default.
• W2080293143 hasConcept C10162356 @default.
• W2080293143 hasConcept C126322002 @default.
• W2080293143 hasConcept C134018914 @default.
• W2080293143 hasConcept C170493617 @default.
• W2080293143 hasConcept C178592051 @default.
• W2080293143 hasConcept C2776785769 @default.
• W2080293143 hasConcept C2776914184 @default.
• W2080293143 hasConcept C2778266237 @default.
• W2080293143 hasConcept C2778938600 @default.
• W2080293143 hasConcept C2909278008 @default.
• W2080293143 hasConcept C71924100 @default.
• W2080293143 hasConcept C89560881 @default.
• W2080293143 hasConceptScore W2080293143C10162356 @default.
• W2080293143 hasConceptScore W2080293143C126322002 @default.
• W2080293143 hasConceptScore W2080293143C134018914 @default.
• W2080293143 hasConceptScore W2080293143C170493617 @default.
• W2080293143 hasConceptScore W2080293143C178592051 @default.
• W2080293143 hasConceptScore W2080293143C2776785769 @default.
• W2080293143 hasConceptScore W2080293143C2776914184 @default.
• W2080293143 hasConceptScore W2080293143C2778266237 @default.
• W2080293143 hasConceptScore W2080293143C2778938600 @default.
• W2080293143 hasConceptScore W2080293143C2909278008 @default.
• W2080293143 hasConceptScore W2080293143C71924100 @default.
• W2080293143 hasConceptScore W2080293143C89560881 @default.
• W2080293143 hasLocation W20802931431 @default.
• W2080293143 hasLocation W20802931432 @default.
• W2080293143 hasOpenAccess W2080293143 @default.
• W2080293143 hasPrimaryLocation W20802931431 @default.
• W2080293143 hasRelatedWork W1487066279 @default.
• W2080293143 hasRelatedWork W2065781224 @default.
• W2080293143 hasRelatedWork W2069998095 @default.
• W2080293143 hasRelatedWork W2076028965 @default.
• W2080293143 hasRelatedWork W2107936051 @default.
• W2080293143 hasRelatedWork W2120895117 @default.
• W2080293143 hasRelatedWork W2131501783 @default.
• W2080293143 hasRelatedWork W2134208261 @default.
• W2080293143 hasRelatedWork W2146403616 @default.
• W2080293143 hasRelatedWork W2154646489 @default.
• W2080293143 hasRelatedWork W2340041946 @default.
• W2080293143 hasRelatedWork W2375379890 @default.
• W2080293143 hasRelatedWork W2410738283 @default.
• W2080293143 hasRelatedWork W24602962 @default.
• W2080293143 hasRelatedWork W2470425713 @default.
• W2080293143 hasRelatedWork W2605968136 @default.
• W2080293143 hasRelatedWork W3007990264 @default.
• W2080293143 hasRelatedWork W3173324763 @default.
• W2080293143 hasRelatedWork W3190062542 @default.
• W2080293143 hasRelatedWork W3195961553 @default.
• W2080293143 isParatext "false" @default.

• next