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- W2080296150 abstract "Few cohort studies have been made in elderly population to study the predictor factors of becoming hypertensive. We describe the results of an urban cohort study of elderly people (>65 years) with an average of following of 3 years (EPICARDIAN study), randomly selected. Mean age 73.3 years old, 45.9% men, who underwent two measurements of BP at the hospital in standard conditions with mercury sphygmomanometer and 3 years later. Anthropometric measurements were made (body mass index (BMI), waist hip ratio (WHR), plasma levels of cholesterol (total, LDL, HDL), triglicerides, glucose, creatinine, uric acid, fibrinogen and hematocrit. Ambulatory blood pressure monitoring was made. An echocardiogram was performed to quantify the left ventricular mass index. From the 420 subjets in the beginning, 23.3% (98 subjects) were normotensives, mean age 72.15 years. Of this group 23 subjects didn’t have a second BP measurement at 3 years because of dead, 9 deaths (2 ictus, 1 MI and 6 non cardiovascular cause) or refusal (14 subjects). Of the 75 normotensives 19 became HT. An statistic analysis (t-test, relative risk estimation, chi-square test) was made in order to investigate possible predictor factors. The waist hip ratio (WHR) was higher (mean 0.04) in the group that became hypertensive (p=0.041). There were no differences between the initial BMI and the one of 3 years later. The relative risk of becoming hypertensive being hyperuricemic is 4.11 (CI 95% 2.28–7.4). The predictors of becoming hypertensive in the elderly sample studied is the waist hip ratio and the hyperuricemia. This remarks the importance of the androgenic obesity. The uric acid can be considered at least in elderly people as an independent marker of cardiovascular risk, in this case of hypertension." @default.
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- W2080296150 date "2000-06-01" @default.
- W2080296150 modified "2023-10-18" @default.
- W2080296150 title "Predictor factors of evolution to hypertension (HT) of normotensive elderly subjets" @default.
- W2080296150 doi "https://doi.org/10.1016/s0895-7061(00)01005-0" @default.
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