FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080301068> ?p ?o ?g. }

• W2080301068 endingPage "1172" @default.
• W2080301068 startingPage "1164" @default.
• W2080301068 abstract "In the treatment of hypertension in renally impaired patients, normalization of blood pressure alone may not be sufficient to prevent significant morbidity to the kidneys. Treatment must reduce pressure in the renal vasculature, otherwise glomerular filtration rate and renal plasma flow will continue to deteriorate. Isradipine, a dihydropyridine calcium-channel blocker, has been investigated as a suitable treatment in this setting. Isradipine maintains glomerular filtration rate, preserves or enhances renal plasma flow, decreases renal vascular resistance, maintains or reduces filtration fraction, and exerts a sustained natriuretic effect, all of which may enable isradipine to slow the rate of progression of renal deterioration. In addition, isradipine may decrease proteinuria and may decrease glomerular capillary pressure by dilating both the efferent and afferent arterioles. Unlike older calcium-channel blockers, isradipine exhibits minimal cardiodepressant activity and is not associated with any negative inotropic effects. It is metabolized in the liver and dosage adjustments may not be necessary when administered to patients with renal insufficiency. Isradipine has a favorable renal effect profile and also has several properties that meet the requirements of other patient populations where an extra measure of antihypertensive safety is required, such as diabetics, dialysis patients, and transplant recipients. Side effects with isradipine are usually mild and transient, occurring in a dose-dependent manner." @default.
• W2080301068 created "2016-06-24" @default.
• W2080301068 creator A5020544805 @default.
• W2080301068 date "1994-12-01" @default.
• W2080301068 modified "2023-10-16" @default.
• W2080301068 title "Calcium-Channel Entry Blocker Therapy for Hypertensive Patients with Concomitant Renal Impairment: A Focus on Isradipine" @default.
• W2080301068 cites W1594879237 @default.
• W2080301068 cites W1966987796 @default.
• W2080301068 cites W1985538241 @default.
• W2080301068 cites W1987101515 @default.
• W2080301068 cites W1987267676 @default.
• W2080301068 cites W1996485736 @default.
• W2080301068 cites W1996992946 @default.
• W2080301068 cites W1998653400 @default.
• W2080301068 cites W1999612914 @default.
• W2080301068 cites W2001913285 @default.
• W2080301068 cites W2007057774 @default.
• W2080301068 cites W2008498491 @default.
• W2080301068 cites W2017029401 @default.
• W2080301068 cites W2022274978 @default.
• W2080301068 cites W2022509296 @default.
• W2080301068 cites W2023666932 @default.
• W2080301068 cites W2025236049 @default.
• W2080301068 cites W2031176100 @default.
• W2080301068 cites W2031829184 @default.
• W2080301068 cites W2037928458 @default.
• W2080301068 cites W2045627765 @default.
• W2080301068 cites W2056252532 @default.
• W2080301068 cites W2061870025 @default.
• W2080301068 cites W2065424149 @default.
• W2080301068 cites W2068173109 @default.
• W2080301068 cites W2069709814 @default.
• W2080301068 cites W2072571357 @default.
• W2080301068 cites W2076163313 @default.
• W2080301068 cites W2080309481 @default.
• W2080301068 cites W2097937391 @default.
• W2080301068 cites W2098465961 @default.
• W2080301068 cites W2114498807 @default.
• W2080301068 cites W2139480984 @default.
• W2080301068 cites W2147676907 @default.
• W2080301068 cites W2153343146 @default.
• W2080301068 cites W2156663584 @default.
• W2080301068 cites W2160381989 @default.
• W2080301068 cites W2162772266 @default.
• W2080301068 cites W2283638085 @default.
• W2080301068 cites W2397572398 @default.
• W2080301068 cites W2410289316 @default.
• W2080301068 cites W2430977444 @default.
• W2080301068 cites W4233901727 @default.
• W2080301068 cites W4244918166 @default.
• W2080301068 cites W4245740719 @default.
• W2080301068 cites W92026005 @default.
• W2080301068 doi "https://doi.org/10.1002/j.1552-4604.1994.tb04727.x" @default.
• W2080301068 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7738211" @default.
• W2080301068 hasPublicationYear "1994" @default.
• W2080301068 type Work @default.
• W2080301068 sameAs 2080301068 @default.
• W2080301068 citedByCount "3" @default.
• W2080301068 crossrefType "journal-article" @default.
• W2080301068 hasAuthorship W2080301068A5020544805 @default.
• W2080301068 hasConcept C119584498 @default.
• W2080301068 hasConcept C126322002 @default.
• W2080301068 hasConcept C126894567 @default.
• W2080301068 hasConcept C134018914 @default.
• W2080301068 hasConcept C142225936 @default.
• W2080301068 hasConcept C159641895 @default.
• W2080301068 hasConcept C164705383 @default.
• W2080301068 hasConcept C21652263 @default.
• W2080301068 hasConcept C2776066529 @default.
• W2080301068 hasConcept C2780356492 @default.
• W2080301068 hasConcept C2780636983 @default.
• W2080301068 hasConcept C2781212610 @default.
• W2080301068 hasConcept C2908929049 @default.
• W2080301068 hasConcept C42219234 @default.
• W2080301068 hasConcept C519063684 @default.
• W2080301068 hasConcept C71924100 @default.
• W2080301068 hasConcept C84393581 @default.
• W2080301068 hasConcept C85520022 @default.
• W2080301068 hasConcept C98274493 @default.
• W2080301068 hasConceptScore W2080301068C119584498 @default.
• W2080301068 hasConceptScore W2080301068C126322002 @default.
• W2080301068 hasConceptScore W2080301068C126894567 @default.
• W2080301068 hasConceptScore W2080301068C134018914 @default.
• W2080301068 hasConceptScore W2080301068C142225936 @default.
• W2080301068 hasConceptScore W2080301068C159641895 @default.
• W2080301068 hasConceptScore W2080301068C164705383 @default.
• W2080301068 hasConceptScore W2080301068C21652263 @default.
• W2080301068 hasConceptScore W2080301068C2776066529 @default.
• W2080301068 hasConceptScore W2080301068C2780356492 @default.
• W2080301068 hasConceptScore W2080301068C2780636983 @default.
• W2080301068 hasConceptScore W2080301068C2781212610 @default.
• W2080301068 hasConceptScore W2080301068C2908929049 @default.
• W2080301068 hasConceptScore W2080301068C42219234 @default.
• W2080301068 hasConceptScore W2080301068C519063684 @default.
• W2080301068 hasConceptScore W2080301068C71924100 @default.
• W2080301068 hasConceptScore W2080301068C84393581 @default.
• W2080301068 hasConceptScore W2080301068C85520022 @default.
• W2080301068 hasConceptScore W2080301068C98274493 @default.

• next