Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080304059> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2080304059 abstract "We established a new human renal cell carcinoma system to study some properties of metastatic renal cancer cells and the influence of the organ environment on their metastatic potential. Renal cell carcinoma obtained from a surgical specimen was dissociated enzymatically. Cells were injected into the subcutis, kidney, cecal wall, and spleen of nude mice. Tumors grew in the subcutis and kidney. Only kidney tumors produced distant metastasis. Subcutaneous tumors were avascular and encapsulated, whereas kidney tumors were highly vascularized and invaded the kidney parenchyma. Cell lines were also established from several spontaneous lung metastases. The most metastatic cell line (LM-6) expressed higher levels of basic fibroblast growth factor, gelatinase, and urokinase activity. These results show that human neoplasms are heterogeneous for biologic properties, that orthotopic implantation is essential for the selection, growth, and metastasis of human renal cell carcinoma cells, and that metastatic cells must possess multiple properties to enable them to complete the process." @default.
- W2080304059 created "2016-06-24" @default.
- W2080304059 creator A5004335726 @default.
- W2080304059 creator A5007321810 @default.
- W2080304059 creator A5021593247 @default.
- W2080304059 creator A5023346773 @default.
- W2080304059 creator A5047335221 @default.
- W2080304059 creator A5054554620 @default.
- W2080304059 creator A5060815247 @default.
- W2080304059 creator A5075851493 @default.
- W2080304059 date "1993-01-01" @default.
- W2080304059 modified "2023-09-27" @default.
- W2080304059 title "THE IMPORTANCE OF ORTHOTOPIC IMPLANTATION TO THE ISOLATION AND BIOLOGICAL CHARACTERIZATION OF A METASTATIC HUMAN CLEAR CELL RENAL-CARCINOMA IN NUDE-MICE" @default.
- W2080304059 doi "https://doi.org/10.3892/ijo.2.1.23" @default.
- W2080304059 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21573511" @default.
- W2080304059 hasPublicationYear "1993" @default.
- W2080304059 type Work @default.
- W2080304059 sameAs 2080304059 @default.
- W2080304059 citedByCount "10" @default.
- W2080304059 countsByYear W20803040592015 @default.
- W2080304059 countsByYear W20803040592016 @default.
- W2080304059 crossrefType "journal-article" @default.
- W2080304059 hasAuthorship W2080304059A5004335726 @default.
- W2080304059 hasAuthorship W2080304059A5007321810 @default.
- W2080304059 hasAuthorship W2080304059A5021593247 @default.
- W2080304059 hasAuthorship W2080304059A5023346773 @default.
- W2080304059 hasAuthorship W2080304059A5047335221 @default.
- W2080304059 hasAuthorship W2080304059A5054554620 @default.
- W2080304059 hasAuthorship W2080304059A5060815247 @default.
- W2080304059 hasAuthorship W2080304059A5075851493 @default.
- W2080304059 hasConcept C121608353 @default.
- W2080304059 hasConcept C134018914 @default.
- W2080304059 hasConcept C142724271 @default.
- W2080304059 hasConcept C1491633281 @default.
- W2080304059 hasConcept C2777472916 @default.
- W2080304059 hasConcept C2777546739 @default.
- W2080304059 hasConcept C2778881546 @default.
- W2080304059 hasConcept C2779013556 @default.
- W2080304059 hasConcept C2780091579 @default.
- W2080304059 hasConcept C2780278673 @default.
- W2080304059 hasConcept C2781068499 @default.
- W2080304059 hasConcept C502942594 @default.
- W2080304059 hasConcept C54355233 @default.
- W2080304059 hasConcept C71924100 @default.
- W2080304059 hasConcept C81885089 @default.
- W2080304059 hasConcept C86803240 @default.
- W2080304059 hasConceptScore W2080304059C121608353 @default.
- W2080304059 hasConceptScore W2080304059C134018914 @default.
- W2080304059 hasConceptScore W2080304059C142724271 @default.
- W2080304059 hasConceptScore W2080304059C1491633281 @default.
- W2080304059 hasConceptScore W2080304059C2777472916 @default.
- W2080304059 hasConceptScore W2080304059C2777546739 @default.
- W2080304059 hasConceptScore W2080304059C2778881546 @default.
- W2080304059 hasConceptScore W2080304059C2779013556 @default.
- W2080304059 hasConceptScore W2080304059C2780091579 @default.
- W2080304059 hasConceptScore W2080304059C2780278673 @default.
- W2080304059 hasConceptScore W2080304059C2781068499 @default.
- W2080304059 hasConceptScore W2080304059C502942594 @default.
- W2080304059 hasConceptScore W2080304059C54355233 @default.
- W2080304059 hasConceptScore W2080304059C71924100 @default.
- W2080304059 hasConceptScore W2080304059C81885089 @default.
- W2080304059 hasConceptScore W2080304059C86803240 @default.
- W2080304059 hasLocation W20803040591 @default.
- W2080304059 hasLocation W20803040592 @default.
- W2080304059 hasOpenAccess W2080304059 @default.
- W2080304059 hasPrimaryLocation W20803040591 @default.
- W2080304059 hasRelatedWork W1884187772 @default.
- W2080304059 hasRelatedWork W196739637 @default.
- W2080304059 hasRelatedWork W2031477339 @default.
- W2080304059 hasRelatedWork W2036640839 @default.
- W2080304059 hasRelatedWork W2052625497 @default.
- W2080304059 hasRelatedWork W2088023845 @default.
- W2080304059 hasRelatedWork W2089099523 @default.
- W2080304059 hasRelatedWork W2104325698 @default.
- W2080304059 hasRelatedWork W2104947013 @default.
- W2080304059 hasRelatedWork W2113027478 @default.
- W2080304059 hasRelatedWork W2113554746 @default.
- W2080304059 hasRelatedWork W2115611042 @default.
- W2080304059 hasRelatedWork W2120427107 @default.
- W2080304059 hasRelatedWork W2165284248 @default.
- W2080304059 hasRelatedWork W2259520070 @default.
- W2080304059 hasRelatedWork W2376159248 @default.
- W2080304059 hasRelatedWork W2401441072 @default.
- W2080304059 hasRelatedWork W2751639769 @default.
- W2080304059 hasRelatedWork W3136531176 @default.
- W2080304059 hasRelatedWork W56771330 @default.
- W2080304059 isParatext "false" @default.
- W2080304059 isRetracted "false" @default.
- W2080304059 magId "2080304059" @default.
- W2080304059 workType "article" @default.