FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080309225> ?p ?o ?g. }

• W2080309225 endingPage "1449" @default.
• W2080309225 startingPage "1437" @default.
• W2080309225 abstract "Aim: In the present study, the influence of SAM on TPMT activity in vivo on human subjects was investigated. Subjects & methods: A total of 1017 donors from the Estonian Genome Center of the University of Tartu (Estonia) were genotyped for common TPMT variants, evaluated for TPMT activity, SAM levels, a set of 19 biochemical and ten hematological parameters and demographic data. Results: After adjustment in multiple regression models and correction for multiple testing, from the 43 factors that were tested, only TPMT genotype (p = 1 × 10 -13 ) and SAM levels (p = 1 × 10 -13 ) were found to significantly influence TPMT activity. The influence of SAM on TPMT activity was more pronounced in TPMT-heterozygous than wild-type individuals. Conclusion: SAM represents a potential pharmacometabolomic marker and therapeutic agent in TPMT-heterozygous subjects. Original submitted 17 February 2014; Revision submitted 16 May 2014" @default.
• W2080309225 created "2016-06-24" @default.
• W2080309225 creator A5026292265 @default.
• W2080309225 creator A5052325580 @default.
• W2080309225 creator A5080937461 @default.
• W2080309225 creator A5081865434 @default.
• W2080309225 creator A5091248250 @default.
• W2080309225 date "2014-08-01" @default.
• W2080309225 modified "2023-09-24" @default.
• W2080309225 title "From pharmacogenetics to pharmacometabolomics: SAM modulates TPMT activity" @default.
• W2080309225 cites W1511937926 @default.
• W2080309225 cites W1602252594 @default.
• W2080309225 cites W1968593126 @default.
• W2080309225 cites W1969154585 @default.
• W2080309225 cites W1977733462 @default.
• W2080309225 cites W1983562154 @default.
• W2080309225 cites W1989369557 @default.
• W2080309225 cites W2012296574 @default.
• W2080309225 cites W2025101573 @default.
• W2080309225 cites W2027950584 @default.
• W2080309225 cites W2033674020 @default.
• W2080309225 cites W2042410622 @default.
• W2080309225 cites W2056432057 @default.
• W2080309225 cites W2057624222 @default.
• W2080309225 cites W2074189093 @default.
• W2080309225 cites W2081308182 @default.
• W2080309225 cites W2084174042 @default.
• W2080309225 cites W2085511279 @default.
• W2080309225 cites W2090273259 @default.
• W2080309225 cites W2095224697 @default.
• W2080309225 cites W2098481310 @default.
• W2080309225 cites W2107261680 @default.
• W2080309225 cites W2114785755 @default.
• W2080309225 cites W2118094114 @default.
• W2080309225 cites W2153052535 @default.
• W2080309225 cites W2161998950 @default.
• W2080309225 cites W2166346311 @default.
• W2080309225 cites W2167481343 @default.
• W2080309225 cites W2335364859 @default.
• W2080309225 cites W2402900764 @default.
• W2080309225 cites W4229642588 @default.
• W2080309225 doi "https://doi.org/10.2217/pgs.14.84" @default.
• W2080309225 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25303295" @default.
• W2080309225 hasPublicationYear "2014" @default.
• W2080309225 type Work @default.
• W2080309225 sameAs 2080309225 @default.
• W2080309225 citedByCount "17" @default.
• W2080309225 countsByYear W20803092252015 @default.
• W2080309225 countsByYear W20803092252016 @default.
• W2080309225 countsByYear W20803092252017 @default.
• W2080309225 countsByYear W20803092252018 @default.
• W2080309225 countsByYear W20803092252019 @default.
• W2080309225 countsByYear W20803092252020 @default.
• W2080309225 countsByYear W20803092252021 @default.
• W2080309225 crossrefType "journal-article" @default.
• W2080309225 hasAuthorship W2080309225A5026292265 @default.
• W2080309225 hasAuthorship W2080309225A5052325580 @default.
• W2080309225 hasAuthorship W2080309225A5080937461 @default.
• W2080309225 hasAuthorship W2080309225A5081865434 @default.
• W2080309225 hasAuthorship W2080309225A5091248250 @default.
• W2080309225 hasBestOaLocation W20803092251 @default.
• W2080309225 hasConcept C104317684 @default.
• W2080309225 hasConcept C126322002 @default.
• W2080309225 hasConcept C135763542 @default.
• W2080309225 hasConcept C185592680 @default.
• W2080309225 hasConcept C207001950 @default.
• W2080309225 hasConcept C2778260677 @default.
• W2080309225 hasConcept C2779134260 @default.
• W2080309225 hasConcept C54355233 @default.
• W2080309225 hasConcept C55775858 @default.
• W2080309225 hasConcept C70917649 @default.
• W2080309225 hasConcept C71924100 @default.
• W2080309225 hasConcept C86803240 @default.
• W2080309225 hasConcept C98274493 @default.
• W2080309225 hasConceptScore W2080309225C104317684 @default.
• W2080309225 hasConceptScore W2080309225C126322002 @default.
• W2080309225 hasConceptScore W2080309225C135763542 @default.
• W2080309225 hasConceptScore W2080309225C185592680 @default.
• W2080309225 hasConceptScore W2080309225C207001950 @default.
• W2080309225 hasConceptScore W2080309225C2778260677 @default.
• W2080309225 hasConceptScore W2080309225C2779134260 @default.
• W2080309225 hasConceptScore W2080309225C54355233 @default.
• W2080309225 hasConceptScore W2080309225C55775858 @default.
• W2080309225 hasConceptScore W2080309225C70917649 @default.
• W2080309225 hasConceptScore W2080309225C71924100 @default.
• W2080309225 hasConceptScore W2080309225C86803240 @default.
• W2080309225 hasConceptScore W2080309225C98274493 @default.
• W2080309225 hasIssue "11" @default.
• W2080309225 hasLocation W20803092251 @default.
• W2080309225 hasLocation W20803092252 @default.
• W2080309225 hasOpenAccess W2080309225 @default.
• W2080309225 hasPrimaryLocation W20803092251 @default.
• W2080309225 hasRelatedWork W199358782 @default.
• W2080309225 hasRelatedWork W1994481782 @default.
• W2080309225 hasRelatedWork W2038433580 @default.
• W2080309225 hasRelatedWork W2076449779 @default.
• W2080309225 hasRelatedWork W2093954596 @default.
• W2080309225 hasRelatedWork W2095027842 @default.

• next