FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080327115> ?p ?o ?g. }

• W2080327115 endingPage "AB197" @default.
• W2080327115 startingPage "AB197" @default.
• W2080327115 abstract "Introduction: Endoscopic resection (ER) is becoming a standard treatment for early gastric cancer (EGC) and nowadays is being performed in an increasing number of patients. Although the complications of the method like bleeding, perforation and significant pain are rare, their prevalence will accordingly increase in the future. A decrease of post ER pain would lead to its wider acceptance. Recent evidence suggests that instillation of local anesthetic both into the peritoneum and the skin incision may be beneficial in minimally invasive surgery such as laparoscopic cholecystectomy. There is no report on lidocaine use during ER, for post-ER analgesia. Aim&Methods: We attempted to reduce the percentage of patients experiencing significant pain by means of local anesthesia injection. We evaluated the action of lidocaine when injected into submucosa during ER. We randomized 17 patients (12 males, age range 51∼80) who underwent ER for early gastric cancer from September to November in 2005, in 2 groups; 8 patients received 0.5% lidocaine with epinephrine while 9 received saline with epinephrine as placebo. All procedures were carried out under standard sedation (midazolam, pentazocine). The patients, operator, and assistant were blinded on the nature of the injected agent. During the procedure we monitored ECG, heart rate, oxygen saturation, and blood pressure. The patients reported the level of pain felt on days 0, 1 and 2 after the procedure and on the same time blinded doctors examined them physically focusing on the existence of epigastric discomfort and tenderness. The level of white blood cell and C-reactive protein was also recorded. Results: No abnormality on ECG, heart rate, oxygen saturation, and blood pressure was seen in any patient of either group. Only one patient out of the eight of the lidocaine group presented abdominal findings contrasting to three patients out of nine in the saline group on day 0. The mean dosage of midazolam necessitated in the lidocaine group (8.5 mg/person) was lower from the one in the placebo group (11.6 mg/person). The dosage of pentazocine was similar. Mean dosage of lidocaine was 195 mg. No episode of lidocaine intoxication, convulsion or arrhythmia was seen. In particular, when the resected tumors were located in the antrum, 40% of the patients belonging to the saline group had abdominal findings at day 0 as compared to none of the lidocaine group. Conclusion: Lidocaine injection into submucosal layer during ER seems to be safe and to reduce pain in the immediate post ER period. Its efficacy should be further investigated." @default.
• W2080327115 created "2016-06-24" @default.
• W2080327115 creator A5007511984 @default.
• W2080327115 creator A5010269859 @default.
• W2080327115 creator A5027302821 @default.
• W2080327115 creator A5029484004 @default.
• W2080327115 creator A5042602006 @default.
• W2080327115 creator A5043651016 @default.
• W2080327115 creator A5056723145 @default.
• W2080327115 creator A5062602632 @default.
• W2080327115 creator A5089864607 @default.
• W2080327115 date "2006-04-01" @default.
• W2080327115 modified "2023-09-25" @default.
• W2080327115 title "Use of Lidocaine Injection During Endoscopic Resection for Early Gastric Cancer" @default.
• W2080327115 doi "https://doi.org/10.1016/j.gie.2006.03.465" @default.
• W2080327115 hasPublicationYear "2006" @default.
• W2080327115 type Work @default.
• W2080327115 sameAs 2080327115 @default.
• W2080327115 citedByCount "0" @default.
• W2080327115 crossrefType "journal-article" @default.
• W2080327115 hasAuthorship W2080327115A5007511984 @default.
• W2080327115 hasAuthorship W2080327115A5010269859 @default.
• W2080327115 hasAuthorship W2080327115A5027302821 @default.
• W2080327115 hasAuthorship W2080327115A5029484004 @default.
• W2080327115 hasAuthorship W2080327115A5042602006 @default.
• W2080327115 hasAuthorship W2080327115A5043651016 @default.
• W2080327115 hasAuthorship W2080327115A5056723145 @default.
• W2080327115 hasAuthorship W2080327115A5062602632 @default.
• W2080327115 hasAuthorship W2080327115A5089864607 @default.
• W2080327115 hasConcept C141071460 @default.
• W2080327115 hasConcept C2775849661 @default.
• W2080327115 hasConcept C2776814716 @default.
• W2080327115 hasConcept C2778000748 @default.
• W2080327115 hasConcept C2778446825 @default.
• W2080327115 hasConcept C2778994108 @default.
• W2080327115 hasConcept C2780149897 @default.
• W2080327115 hasConcept C2780820201 @default.
• W2080327115 hasConcept C31174226 @default.
• W2080327115 hasConcept C42219234 @default.
• W2080327115 hasConcept C71924100 @default.
• W2080327115 hasConceptScore W2080327115C141071460 @default.
• W2080327115 hasConceptScore W2080327115C2775849661 @default.
• W2080327115 hasConceptScore W2080327115C2776814716 @default.
• W2080327115 hasConceptScore W2080327115C2778000748 @default.
• W2080327115 hasConceptScore W2080327115C2778446825 @default.
• W2080327115 hasConceptScore W2080327115C2778994108 @default.
• W2080327115 hasConceptScore W2080327115C2780149897 @default.
• W2080327115 hasConceptScore W2080327115C2780820201 @default.
• W2080327115 hasConceptScore W2080327115C31174226 @default.
• W2080327115 hasConceptScore W2080327115C42219234 @default.
• W2080327115 hasConceptScore W2080327115C71924100 @default.
• W2080327115 hasIssue "5" @default.
• W2080327115 hasLocation W20803271151 @default.
• W2080327115 hasOpenAccess W2080327115 @default.
• W2080327115 hasPrimaryLocation W20803271151 @default.
• W2080327115 hasRelatedWork W1979552852 @default.
• W2080327115 hasRelatedWork W1980747826 @default.
• W2080327115 hasRelatedWork W2022627108 @default.
• W2080327115 hasRelatedWork W2023060129 @default.
• W2080327115 hasRelatedWork W2024760007 @default.
• W2080327115 hasRelatedWork W2145944150 @default.
• W2080327115 hasRelatedWork W2377615103 @default.
• W2080327115 hasRelatedWork W4237983599 @default.
• W2080327115 hasRelatedWork W71635838 @default.
• W2080327115 hasRelatedWork W89320804 @default.
• W2080327115 hasVolume "63" @default.
• W2080327115 isParatext "false" @default.
• W2080327115 isRetracted "false" @default.
• W2080327115 magId "2080327115" @default.
• W2080327115 workType "article" @default.