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- W2080338330 abstract "Two experiments report retarded physiological and behavioral development of rats prenatally exposed to a sequence of rapid, brief decompressions to 6,000 ft. In Experiment I, prenatally treated young gained weight more slowly than controls, acquired climbing skills at a later age, and ambulated less in an open field at 32 days of age. In Experiment 2, open-field data pro vided evidence for a critical period during the first 12 days of gestation. Studies employing real or simulated altitudes in excess of 10,000 ft provide most of the evidence for the prenatal influence of low barometric pressure. None theless, the investigation of decompressions, involving less than IO,OOO-ft altitude change, seems equally interesting. In addition to those who live in decompressed atmospheres below 10,000 ft, many individuals experience similarly mild decompressions during air travel. Effects of these mild decompressions are unknown, but high-altitude studies suggest that reduced barometric pressure generally retards both fetal (Chiodi, 1953 ; Grahn & Kratchman, 1963 ; Johnson & Roofe, 1965 ; Lichty , Ting, Burns, & Dyar, 1957 ; Mazess, 1965 ; McClung, 1969; Moore & Price, 1948) and newborn (McCullough & Blackman, 1976) development. 'Th e- ' present study attempts to extend these findings to prenatally administered , rapid, brief decompressions to 6,000 ft, like those experienced during air travel. In the first experiment, rats receiving treatments for 20 days of gestation were observed for body-weight gains and various motor skills, including righting, grasping, walking an inclined plane, and climbing. It was expected that the stressor would reduce body weights of pups and retard appearance of these motor skills relative to untreated controls. Though McCullough and Blackman (1976) reported that acute anoxia did not affect emotionality of 53-day-old rats, weanlings in the second experiment were subjected to open-field testing because decompression exposes animals to potential stressors in addition to hypoxia . Experiment 2 also attempted to isolate a critical period during which" @default.
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- W2080338330 date "1978-10-01" @default.
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- W2080338330 title "Effects of mild prenatal decompressions on growth and behavior in the rat" @default.
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- W2080338330 doi "https://doi.org/10.3758/bf03329698" @default.
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