Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080384080> ?p ?o ?g. }
- W2080384080 endingPage "13380" @default.
- W2080384080 startingPage "13375" @default.
- W2080384080 abstract "The response regulator protein of bacterial chemotaxis, CheY, is representative of a large family of signal transduction proteins that function as phosphorylation-activated switches to regulate the activities of associated effector domains. These regulators catalyze the metal ion-dependent phosphoryl transfer and dephosphorylation reactions that control the effector activities. The crystal structures of Salmonella typhimurium CheY with and without Mg2+ bound at the active site have been determined and refined at 1.8-A resolution. While the overall structures of metal-bound and metal-free CheY are similar, significant rearrangements occur within the active site involving the three most highly conserved residues of the response regulator family. Conservation of the cluster of carboxylate side chains at the active site of response regulator domains can be rationalized in terms of their role in coordinating the catalytically essential divalent metal ion. The Mg2+ coordination geometry provides insights to the mechanism of phosphoryl transfer." @default.
- W2080384080 created "2016-06-24" @default.
- W2080384080 creator A5006925296 @default.
- W2080384080 creator A5007934367 @default.
- W2080384080 creator A5014900252 @default.
- W2080384080 creator A5039365328 @default.
- W2080384080 creator A5074597936 @default.
- W2080384080 creator A5082906519 @default.
- W2080384080 creator A5090299931 @default.
- W2080384080 date "1993-12-14" @default.
- W2080384080 modified "2023-10-16" @default.
- W2080384080 title "Structure of the magnesium-bound form of CheY and mechanism of phosphoryl transfer in bacterial chemotaxis" @default.
- W2080384080 cites W1516216944 @default.
- W2080384080 cites W1520565605 @default.
- W2080384080 cites W1564890115 @default.
- W2080384080 cites W1574312817 @default.
- W2080384080 cites W1597272291 @default.
- W2080384080 cites W1601687245 @default.
- W2080384080 cites W1608052268 @default.
- W2080384080 cites W1838580001 @default.
- W2080384080 cites W1848092381 @default.
- W2080384080 cites W189861307 @default.
- W2080384080 cites W1971085025 @default.
- W2080384080 cites W1972642574 @default.
- W2080384080 cites W1991022642 @default.
- W2080384080 cites W1996283160 @default.
- W2080384080 cites W2013083986 @default.
- W2080384080 cites W2028231353 @default.
- W2080384080 cites W2048205348 @default.
- W2080384080 cites W2051830305 @default.
- W2080384080 cites W2064860710 @default.
- W2080384080 cites W2068412045 @default.
- W2080384080 cites W2079852902 @default.
- W2080384080 cites W2091276334 @default.
- W2080384080 cites W2099630547 @default.
- W2080384080 cites W2108141139 @default.
- W2080384080 cites W2118129275 @default.
- W2080384080 cites W2127096639 @default.
- W2080384080 cites W2153630542 @default.
- W2080384080 cites W2167950038 @default.
- W2080384080 cites W4245067683 @default.
- W2080384080 cites W4250602387 @default.
- W2080384080 cites W6672265 @default.
- W2080384080 doi "https://doi.org/10.1021/bi00212a001" @default.
- W2080384080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8257674" @default.
- W2080384080 hasPublicationYear "1993" @default.
- W2080384080 type Work @default.
- W2080384080 sameAs 2080384080 @default.
- W2080384080 citedByCount "212" @default.
- W2080384080 countsByYear W20803840802012 @default.
- W2080384080 countsByYear W20803840802013 @default.
- W2080384080 countsByYear W20803840802014 @default.
- W2080384080 countsByYear W20803840802015 @default.
- W2080384080 countsByYear W20803840802016 @default.
- W2080384080 countsByYear W20803840802017 @default.
- W2080384080 countsByYear W20803840802018 @default.
- W2080384080 countsByYear W20803840802019 @default.
- W2080384080 countsByYear W20803840802020 @default.
- W2080384080 countsByYear W20803840802021 @default.
- W2080384080 countsByYear W20803840802022 @default.
- W2080384080 countsByYear W20803840802023 @default.
- W2080384080 crossrefType "journal-article" @default.
- W2080384080 hasAuthorship W2080384080A5006925296 @default.
- W2080384080 hasAuthorship W2080384080A5007934367 @default.
- W2080384080 hasAuthorship W2080384080A5014900252 @default.
- W2080384080 hasAuthorship W2080384080A5039365328 @default.
- W2080384080 hasAuthorship W2080384080A5074597936 @default.
- W2080384080 hasAuthorship W2080384080A5082906519 @default.
- W2080384080 hasAuthorship W2080384080A5090299931 @default.
- W2080384080 hasConcept C104317684 @default.
- W2080384080 hasConcept C107824862 @default.
- W2080384080 hasConcept C11960822 @default.
- W2080384080 hasConcept C12554922 @default.
- W2080384080 hasConcept C166342909 @default.
- W2080384080 hasConcept C170493617 @default.
- W2080384080 hasConcept C178666793 @default.
- W2080384080 hasConcept C178790620 @default.
- W2080384080 hasConcept C181199279 @default.
- W2080384080 hasConcept C181912034 @default.
- W2080384080 hasConcept C185592680 @default.
- W2080384080 hasConcept C2778074193 @default.
- W2080384080 hasConcept C2781196521 @default.
- W2080384080 hasConcept C2993175405 @default.
- W2080384080 hasConcept C41183919 @default.
- W2080384080 hasConcept C51785407 @default.
- W2080384080 hasConcept C54166955 @default.
- W2080384080 hasConcept C544153396 @default.
- W2080384080 hasConcept C55493867 @default.
- W2080384080 hasConcept C6929976 @default.
- W2080384080 hasConcept C71240020 @default.
- W2080384080 hasConcept C86803240 @default.
- W2080384080 hasConceptScore W2080384080C104317684 @default.
- W2080384080 hasConceptScore W2080384080C107824862 @default.
- W2080384080 hasConceptScore W2080384080C11960822 @default.
- W2080384080 hasConceptScore W2080384080C12554922 @default.
- W2080384080 hasConceptScore W2080384080C166342909 @default.
- W2080384080 hasConceptScore W2080384080C170493617 @default.
- W2080384080 hasConceptScore W2080384080C178666793 @default.