Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080387901> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2080387901 endingPage "110" @default.
- W2080387901 startingPage "105" @default.
- W2080387901 abstract "Abstract Wound healing is a sum of mechanisms that have to be finely modulated to reconstitute a tissue similar to the original. Several pathologies induce a decrease of healing rate and patients have to be treated to help the closure of wound. Glycosaminoglycan (GAG) mimetics have proven to be valuable in stimulating wound healing. In this study, galactofucan (fucoidan) was extracted from the brown seaweed Saccharina longicruris during two harvest periods (M05 and N05 fractions). Crude galactofucan M05 and N05 were subjected to radical depolymerization (RDP) for 4 h to obtain 2 RDP fractions (M05 RDP and N05 RDP fractions). Each fraction was added on cultured dermal fibroblasts and growth rate, collagen and MMP secretion were analyzed after treatment. Crude and RDP galactofucan influenced fibroblast growth, apoptosis and the synthesis of matrix metalloproteinase (MMP) and collagen according to the molecular weight of the polymer. Both crude galactofucan extracts reduced cell growth and increased MMP secretion, whereas only M05 stimulated apoptosis. By contrast, RDP fractions significantly increased collagen-I secretion and have no negative effect on fibroblast proliferation. Thus, crude and RDP galactofucan exhibit different metabolic activities on fibroblasts, which may be of interest in the area of wound healing." @default.
- W2080387901 created "2016-06-24" @default.
- W2080387901 creator A5026720673 @default.
- W2080387901 creator A5032085068 @default.
- W2080387901 creator A5036189031 @default.
- W2080387901 creator A5050433947 @default.
- W2080387901 date "2013-04-01" @default.
- W2080387901 modified "2023-10-17" @default.
- W2080387901 title "Human skin fibroblast response is differentially regulated by galactofucan and low molecular weight galactofucan" @default.
- W2080387901 cites W1530924711 @default.
- W2080387901 cites W1966785445 @default.
- W2080387901 cites W1970227771 @default.
- W2080387901 cites W1970579342 @default.
- W2080387901 cites W1980716344 @default.
- W2080387901 cites W1980921956 @default.
- W2080387901 cites W1989944421 @default.
- W2080387901 cites W1997818663 @default.
- W2080387901 cites W2000453685 @default.
- W2080387901 cites W2045317411 @default.
- W2080387901 cites W2058890992 @default.
- W2080387901 cites W2070753660 @default.
- W2080387901 cites W2072517212 @default.
- W2080387901 cites W2072823367 @default.
- W2080387901 cites W2077735637 @default.
- W2080387901 cites W2084334139 @default.
- W2080387901 cites W2089973870 @default.
- W2080387901 cites W2090632077 @default.
- W2080387901 cites W2109148114 @default.
- W2080387901 cites W2111195746 @default.
- W2080387901 cites W2120155938 @default.
- W2080387901 cites W2140864291 @default.
- W2080387901 cites W2149769274 @default.
- W2080387901 cites W2168439058 @default.
- W2080387901 cites W2325727928 @default.
- W2080387901 doi "https://doi.org/10.1016/j.bcdf.2013.03.004" @default.
- W2080387901 hasPublicationYear "2013" @default.
- W2080387901 type Work @default.
- W2080387901 sameAs 2080387901 @default.
- W2080387901 citedByCount "16" @default.
- W2080387901 countsByYear W20803879012014 @default.
- W2080387901 countsByYear W20803879012015 @default.
- W2080387901 countsByYear W20803879012017 @default.
- W2080387901 countsByYear W20803879012018 @default.
- W2080387901 countsByYear W20803879012019 @default.
- W2080387901 countsByYear W20803879012020 @default.
- W2080387901 countsByYear W20803879012021 @default.
- W2080387901 countsByYear W20803879012022 @default.
- W2080387901 countsByYear W20803879012023 @default.
- W2080387901 crossrefType "journal-article" @default.
- W2080387901 hasAuthorship W2080387901A5026720673 @default.
- W2080387901 hasAuthorship W2080387901A5032085068 @default.
- W2080387901 hasAuthorship W2080387901A5036189031 @default.
- W2080387901 hasAuthorship W2080387901A5050433947 @default.
- W2080387901 hasConcept C2777459323 @default.
- W2080387901 hasConcept C2780381497 @default.
- W2080387901 hasConcept C54355233 @default.
- W2080387901 hasConcept C81885089 @default.
- W2080387901 hasConcept C86803240 @default.
- W2080387901 hasConcept C95444343 @default.
- W2080387901 hasConceptScore W2080387901C2777459323 @default.
- W2080387901 hasConceptScore W2080387901C2780381497 @default.
- W2080387901 hasConceptScore W2080387901C54355233 @default.
- W2080387901 hasConceptScore W2080387901C81885089 @default.
- W2080387901 hasConceptScore W2080387901C86803240 @default.
- W2080387901 hasConceptScore W2080387901C95444343 @default.
- W2080387901 hasIssue "2" @default.
- W2080387901 hasLocation W20803879011 @default.
- W2080387901 hasOpenAccess W2080387901 @default.
- W2080387901 hasPrimaryLocation W20803879011 @default.
- W2080387901 hasRelatedWork W2008434851 @default.
- W2080387901 hasRelatedWork W2011426855 @default.
- W2080387901 hasRelatedWork W2030272140 @default.
- W2080387901 hasRelatedWork W2080002581 @default.
- W2080387901 hasRelatedWork W2364999632 @default.
- W2080387901 hasRelatedWork W2377215116 @default.
- W2080387901 hasRelatedWork W2561211421 @default.
- W2080387901 hasRelatedWork W2949846784 @default.
- W2080387901 hasRelatedWork W3081427387 @default.
- W2080387901 hasRelatedWork W3124108302 @default.
- W2080387901 hasVolume "1" @default.
- W2080387901 isParatext "false" @default.
- W2080387901 isRetracted "false" @default.
- W2080387901 magId "2080387901" @default.
- W2080387901 workType "article" @default.