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- W2080388300 abstract "The serum concentrations of the glycoprotein α-subunit and the FSH β-subunit were determined basally and in response to gonadotropin-releasing hormone (GnRH) in 12 men who had pituitary adenomas associated with selective hypersecretion of FSH. The same determinations were also made in men who had primary hypogonadism and serum FSH concentrations elevated to a degree similar to that of the men who had pituitary adenomas, as well as in two groups of normal men matched in age to the men with pituitary adenomas and the men with primary hypogonadism, respectively. Because intact FSH cross-reacted in the α-subunit and FSH β-subunit assays and intact LH cross-reacted in the α-subunit assay, the values for serum concentrations of both subunits were corrected for the contributions of the intact hormones. The FSH β-subunit was also determined in post-GnRH sera after separating it from intact FSH by gel filtration chromatography. The serum α-subunit response to GnRH was less in the men who had pituitary adenomas tha..." @default.
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- W2080388300 date "1980-09-01" @default.
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- W2080388300 title "Abnormal Secretion of Glycoprotein α-Subunit and Follicle-Stimulating Hormone (FSH) β-Subunit in Men with Pituitary Adenomas and FSH Hypersecretion*" @default.
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- W2080388300 doi "https://doi.org/10.1210/jcem-51-3-579" @default.
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