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- W2080408013 abstract "The exploration of different routes leading to the stereoselective synthesis of the neuritogenic steroid withanolide A is reported in full detail. Notable features of the synthesis include a Corey–Seebach homologation, a vinylogous aldol reaction, a singlet oxygen Schenck-ene reaction, and finally, a late-stage Wharton transposition. Semi-synthetic elaboration of the natural product resulted in 15 derivatives allowing a better understanding of its inherent reactivity pattern as well as its biological properties related to neuronal differentiation and neurite outgrowth." @default.
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- W2080408013 date "2013-01-01" @default.
- W2080408013 modified "2023-10-09" @default.
- W2080408013 title "Withanolide A: synthesis and structural requirements for neurite outgrowth" @default.
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- W2080408013 doi "https://doi.org/10.1039/c3sc50653c" @default.
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