FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080408103> ?p ?o ?g. }

• W2080408103 endingPage "59" @default.
• W2080408103 startingPage "50" @default.
• W2080408103 abstract "Using quantitative autoradiography, we investigated the effect of intracarotid infusions of hyperosmolar mannitol solutions on capillary permeability and blood flow. Capillary permeability, expressed in terms of a blood-to-tissue transfer constant (K), was determined in two rat brain tumor models by measuring the entry of 14C-alpha aminoisobutyric acid into brian tumor, into brain tissue adjacent to tumor, and into cortex. Cerebral blood flow was determined by measuring the uptake of 14C-iodoantipyrine in one rat brain tumor model. Blood flow was examined in the same regions as K, as well as in the corpus callosum. Before mannitol administration, K values in both Walker 256 (W256) carcinosarcoma and C6 gliomas were much higher than those in cortex. C6 gliomas were about three times more permeable than were W256 tumors. There was a direct correlation between tumor size and increased capillary permeability. Mannitol at a concentration of 1.37 M did not increase the K values for either tumor or adjacent tissue. At 1.6 M, mannitol increased the K values for both tumors (1.7-fold in C6 glioma and 13-fold in W256) as well as for adjacent tissue. At both concentrations, mannitol markedly increased cortical K values in all groups: by 48-to 72-fold at 1.37 M and by 90- to 105-fold at 1.6 M. The net effect of the mannitol was to reverse the tumor-to-cortex permeability relationship. Cortical blood flow increased modestly after intracarotid mannitol administration on both sides of the brain. These data provide little justification for using intracarotid mannitol during chemotherapy of human brain tumors." @default.
• W2080408103 created "2016-06-24" @default.
• W2080408103 creator A5010283815 @default.
• W2080408103 creator A5017922880 @default.
• W2080408103 creator A5020555628 @default.
• W2080408103 creator A5040049908 @default.
• W2080408103 creator A5065765773 @default.
• W2080408103 creator A5088535980 @default.
• W2080408103 date "1986-01-01" @default.
• W2080408103 modified "2023-09-26" @default.
• W2080408103 title "Opening the blood-brain and blood-tumor barriers in experimental rat brain tumors: The effect of intracarotid hyperosmolar mannitol on capillary permeability and blood flow" @default.
• W2080408103 cites W1968963925 @default.
• W2080408103 cites W1982180654 @default.
• W2080408103 cites W1985463945 @default.
• W2080408103 cites W1993997561 @default.
• W2080408103 cites W2007320933 @default.
• W2080408103 cites W2007935128 @default.
• W2080408103 cites W2018148950 @default.
• W2080408103 cites W2022784058 @default.
• W2080408103 cites W2039452657 @default.
• W2080408103 cites W2042526601 @default.
• W2080408103 cites W2063991783 @default.
• W2080408103 cites W2069465707 @default.
• W2080408103 cites W2080086992 @default.
• W2080408103 cites W2092156555 @default.
• W2080408103 cites W2093528853 @default.
• W2080408103 cites W2108887091 @default.
• W2080408103 cites W2138276106 @default.
• W2080408103 cites W2152038397 @default.
• W2080408103 cites W2160371769 @default.
• W2080408103 cites W2310907465 @default.
• W2080408103 cites W2328901077 @default.
• W2080408103 doi "https://doi.org/10.1002/ana.410190110" @default.
• W2080408103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3080944" @default.
• W2080408103 hasPublicationYear "1986" @default.
• W2080408103 type Work @default.
• W2080408103 sameAs 2080408103 @default.
• W2080408103 citedByCount "121" @default.
• W2080408103 countsByYear W20804081032012 @default.
• W2080408103 countsByYear W20804081032013 @default.
• W2080408103 countsByYear W20804081032014 @default.
• W2080408103 countsByYear W20804081032015 @default.
• W2080408103 countsByYear W20804081032016 @default.
• W2080408103 countsByYear W20804081032017 @default.
• W2080408103 countsByYear W20804081032018 @default.
• W2080408103 countsByYear W20804081032020 @default.
• W2080408103 countsByYear W20804081032021 @default.
• W2080408103 countsByYear W20804081032023 @default.
• W2080408103 crossrefType "journal-article" @default.
• W2080408103 hasAuthorship W2080408103A5010283815 @default.
• W2080408103 hasAuthorship W2080408103A5017922880 @default.
• W2080408103 hasAuthorship W2080408103A5020555628 @default.
• W2080408103 hasAuthorship W2080408103A5040049908 @default.
• W2080408103 hasAuthorship W2080408103A5065765773 @default.
• W2080408103 hasAuthorship W2080408103A5088535980 @default.
• W2080408103 hasConcept C113045295 @default.
• W2080408103 hasConcept C120882062 @default.
• W2080408103 hasConcept C126322002 @default.
• W2080408103 hasConcept C134018914 @default.
• W2080408103 hasConcept C142724271 @default.
• W2080408103 hasConcept C157767197 @default.
• W2080408103 hasConcept C158846371 @default.
• W2080408103 hasConcept C185592680 @default.
• W2080408103 hasConcept C2778227246 @default.
• W2080408103 hasConcept C2778402981 @default.
• W2080408103 hasConcept C2778445172 @default.
• W2080408103 hasConcept C2779130545 @default.
• W2080408103 hasConcept C41625074 @default.
• W2080408103 hasConcept C502942594 @default.
• W2080408103 hasConcept C529278444 @default.
• W2080408103 hasConcept C55493867 @default.
• W2080408103 hasConcept C71924100 @default.
• W2080408103 hasConceptScore W2080408103C113045295 @default.
• W2080408103 hasConceptScore W2080408103C120882062 @default.
• W2080408103 hasConceptScore W2080408103C126322002 @default.
• W2080408103 hasConceptScore W2080408103C134018914 @default.
• W2080408103 hasConceptScore W2080408103C142724271 @default.
• W2080408103 hasConceptScore W2080408103C157767197 @default.
• W2080408103 hasConceptScore W2080408103C158846371 @default.
• W2080408103 hasConceptScore W2080408103C185592680 @default.
• W2080408103 hasConceptScore W2080408103C2778227246 @default.
• W2080408103 hasConceptScore W2080408103C2778402981 @default.
• W2080408103 hasConceptScore W2080408103C2778445172 @default.
• W2080408103 hasConceptScore W2080408103C2779130545 @default.
• W2080408103 hasConceptScore W2080408103C41625074 @default.
• W2080408103 hasConceptScore W2080408103C502942594 @default.
• W2080408103 hasConceptScore W2080408103C529278444 @default.
• W2080408103 hasConceptScore W2080408103C55493867 @default.
• W2080408103 hasConceptScore W2080408103C71924100 @default.
• W2080408103 hasIssue "1" @default.
• W2080408103 hasLocation W20804081031 @default.
• W2080408103 hasLocation W20804081032 @default.
• W2080408103 hasOpenAccess W2080408103 @default.
• W2080408103 hasPrimaryLocation W20804081031 @default.
• W2080408103 hasRelatedWork W1968323492 @default.
• W2080408103 hasRelatedWork W1972695634 @default.
• W2080408103 hasRelatedWork W1987682444 @default.
• W2080408103 hasRelatedWork W2054775178 @default.

• next