FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080411753> ?p ?o ?g. }

• W2080411753 endingPage "560" @default.
• W2080411753 startingPage "548" @default.
• W2080411753 abstract "Abnormal action potentials in myocytes adjacent to > 2-month-old feline LV myocardial infarcts (MI) may reflect alterations in Ca2+ currents (Ica).We compared ICa, at 36 degrees C, in subendocardial myocytes isolated from areas adjacent to MI and to ICa in cells from remote areas (> 4 mm away; REM) and control cells from similar regions in normal hearts. Control (CON) myocytes had membrane capacitance of 234 +/- 10 pF (n = 81 cells) compared to 305 +/- 14 pF in REM (71 cells; P < 0.05 from CON) and 237 +/- 11 pF (n = 55 cells) in MI (not different from CON). From Vh = -40 mV; peak ICa elicited by test potentials (-35 to +70 mV) were significantly larger in CON (-1746 +/- 123 pA) and REM (-1795 +/- 142 pA) compared to MI (-1352 +/- 129 pA) (P < 0.05). Peak ICa density was significantly reduced in REM (-6.0 +/- 0.4 pA/pF) or MI (-5.7 +/- 0.4 pA/pF, P < 0.05) compared to CON (-7.5 +/- 0.4 pA/pF). Double exponential ICa decay was similar among groups. Half-inactivation potential (V0.5) was significantly shifted (hyperpolarizing direction) for MI (-29.1 +/- 2.6 mV) and REM (-24.6 +/- 1.2 mV) myocytes compared to -20.3 +/- 1.0 mV in CON. MI slope factor (k; 9.0 +/- 0.5) was significantly different from CON (6.8 +/- 0.3) and REM (7.3 +/- 0.4). No differences in time course of recovery from inactivation were noted. Five millimolar Ba2+o produced significant increases in ICa in CON and REM but an attenuated response in MI. Bay K8644 (1 microM) produced similar ICa increase in all groups. ICa increase due to isoproterenol (1 microM) in MI and REM was half that in CON, but there were no differences in increased ICa responses among groups following phenylephrine (10 microM).Reduced ICa density in REM reflects cell hypertrophy, whereas altered ICa of MI may reflect altered channel structure and/or function." @default.
• W2080411753 created "2016-06-24" @default.
• W2080411753 creator A5001976267 @default.
• W2080411753 creator A5005691727 @default.
• W2080411753 creator A5031751761 @default.
• W2080411753 creator A5066655594 @default.
• W2080411753 creator A5072886850 @default.
• W2080411753 date "1997-05-01" @default.
• W2080411753 modified "2023-10-16" @default.
• W2080411753 title "Regional Gradation of L-Type Calcium Currents in the Feline Heart with a Healed Myocardial Infarct" @default.
• W2080411753 cites W1899877571 @default.
• W2080411753 cites W1972554997 @default.
• W2080411753 cites W1972906867 @default.
• W2080411753 cites W1974695277 @default.
• W2080411753 cites W1981757294 @default.
• W2080411753 cites W1984740693 @default.
• W2080411753 cites W1986189505 @default.
• W2080411753 cites W1987698925 @default.
• W2080411753 cites W2005059919 @default.
• W2080411753 cites W2009667219 @default.
• W2080411753 cites W2014203449 @default.
• W2080411753 cites W2016584532 @default.
• W2080411753 cites W2019654282 @default.
• W2080411753 cites W2020016543 @default.
• W2080411753 cites W2024391445 @default.
• W2080411753 cites W2026187249 @default.
• W2080411753 cites W2026275430 @default.
• W2080411753 cites W2054681700 @default.
• W2080411753 cites W2059364171 @default.
• W2080411753 cites W2059521837 @default.
• W2080411753 cites W2063558853 @default.
• W2080411753 cites W2072441490 @default.
• W2080411753 cites W2077829982 @default.
• W2080411753 cites W2080727341 @default.
• W2080411753 cites W2081212418 @default.
• W2080411753 cites W2086455487 @default.
• W2080411753 cites W2098238167 @default.
• W2080411753 cites W2103364644 @default.
• W2080411753 cites W2116323054 @default.
• W2080411753 cites W2127799844 @default.
• W2080411753 cites W2160117204 @default.
• W2080411753 cites W2163958661 @default.
• W2080411753 cites W2332286287 @default.
• W2080411753 doi "https://doi.org/10.1111/j.1540-8167.1997.tb00823.x" @default.
• W2080411753 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9160231" @default.
• W2080411753 hasPublicationYear "1997" @default.
• W2080411753 type Work @default.
• W2080411753 sameAs 2080411753 @default.
• W2080411753 citedByCount "27" @default.
• W2080411753 countsByYear W20804117532012 @default.
• W2080411753 countsByYear W20804117532013 @default.
• W2080411753 countsByYear W20804117532017 @default.
• W2080411753 countsByYear W20804117532018 @default.
• W2080411753 countsByYear W20804117532021 @default.
• W2080411753 crossrefType "journal-article" @default.
• W2080411753 hasAuthorship W2080411753A5001976267 @default.
• W2080411753 hasAuthorship W2080411753A5005691727 @default.
• W2080411753 hasAuthorship W2080411753A5031751761 @default.
• W2080411753 hasAuthorship W2080411753A5066655594 @default.
• W2080411753 hasAuthorship W2080411753A5072886850 @default.
• W2080411753 hasConcept C12554922 @default.
• W2080411753 hasConcept C126322002 @default.
• W2080411753 hasConcept C134018914 @default.
• W2080411753 hasConcept C146403970 @default.
• W2080411753 hasConcept C164705383 @default.
• W2080411753 hasConcept C181911157 @default.
• W2080411753 hasConcept C185263204 @default.
• W2080411753 hasConcept C207200792 @default.
• W2080411753 hasConcept C500558357 @default.
• W2080411753 hasConcept C71924100 @default.
• W2080411753 hasConcept C86803240 @default.
• W2080411753 hasConceptScore W2080411753C12554922 @default.
• W2080411753 hasConceptScore W2080411753C126322002 @default.
• W2080411753 hasConceptScore W2080411753C134018914 @default.
• W2080411753 hasConceptScore W2080411753C146403970 @default.
• W2080411753 hasConceptScore W2080411753C164705383 @default.
• W2080411753 hasConceptScore W2080411753C181911157 @default.
• W2080411753 hasConceptScore W2080411753C185263204 @default.
• W2080411753 hasConceptScore W2080411753C207200792 @default.
• W2080411753 hasConceptScore W2080411753C500558357 @default.
• W2080411753 hasConceptScore W2080411753C71924100 @default.
• W2080411753 hasConceptScore W2080411753C86803240 @default.
• W2080411753 hasIssue "5" @default.
• W2080411753 hasLocation W20804117531 @default.
• W2080411753 hasLocation W20804117532 @default.
• W2080411753 hasOpenAccess W2080411753 @default.
• W2080411753 hasPrimaryLocation W20804117531 @default.
• W2080411753 hasRelatedWork W192089584 @default.
• W2080411753 hasRelatedWork W1977151728 @default.
• W2080411753 hasRelatedWork W1978862208 @default.
• W2080411753 hasRelatedWork W2055981675 @default.
• W2080411753 hasRelatedWork W2062059350 @default.
• W2080411753 hasRelatedWork W2068259322 @default.
• W2080411753 hasRelatedWork W2085819972 @default.
• W2080411753 hasRelatedWork W2395056800 @default.
• W2080411753 hasRelatedWork W2466115554 @default.
• W2080411753 hasRelatedWork W4383955847 @default.
• W2080411753 hasVolume "8" @default.

• next