Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080431174> ?p ?o ?g. }
- W2080431174 endingPage "122" @default.
- W2080431174 startingPage "122" @default.
- W2080431174 abstract "To examine the responses to early IV administration of an anticoagulant or placebo started within 24 hours of stroke among persons with an ipsilateral occlusion or severe stenosis of the internal carotid artery (ICA) identified by carotid duplex imaging.Patients with ischemic stroke of the cerebral hemisphere secondary to an ipsilateral occlusion or severe stenosis of the ICA generally have a poor prognosis. Early, accurate identification of these patients might permit improved treatment.Exploratory analysis of outcomes at 7 days and 3 months was performed among patients enrolled in the Trial of Org 10172 in Acute Stroke Treatment (TOAST) who had an ischemic stroke in the cerebral hemisphere ipsilateral to an occlusion or a stenosis >50% of the ICA identified by carotid duplex imaging.Regardless of treatment, patients with duplex evidence of an occlusion of the ICA had more severe strokes and poorer outcomes at 7 days and 3 months than patients who had a stenosis. Favorable outcomes at 7 days were noted in 64 of 119 patients given danaparoid (53.8%) and 41 of 108 patients treated with placebo (38.0%; p = 0.023). By 3 months, favorable outcomes were noted in 82 patients given danaparoid (68.3%) and 58 patients administered placebo (53.2%; p = 0.021).Early identification by duplex imaging of an occlusion or severe stenosis of the ICA ipsilateral to a hemispheric ischemic stroke might improve selection of patients who could be treated with emergent anticoagulation. Further testing of this approach is needed." @default.
- W2080431174 created "2016-06-24" @default.
- W2080431174 creator A5007298743 @default.
- W2080431174 creator A5020265434 @default.
- W2080431174 creator A5029167216 @default.
- W2080431174 creator A5036176385 @default.
- W2080431174 creator A5050366628 @default.
- W2080431174 creator A5057930855 @default.
- W2080431174 creator A5061154632 @default.
- W2080431174 creator A5063180827 @default.
- W2080431174 date "1999-07-01" @default.
- W2080431174 modified "2023-09-27" @default.
- W2080431174 title "Antithrombotic treatment of ischemic stroke among patients with occlusion or severe stenosis of the internal carotid artery: A report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST)" @default.
- W2080431174 cites W1973982955 @default.
- W2080431174 cites W1988354065 @default.
- W2080431174 cites W1994922079 @default.
- W2080431174 cites W2095025222 @default.
- W2080431174 cites W2124868278 @default.
- W2080431174 cites W2127424330 @default.
- W2080431174 cites W2138595885 @default.
- W2080431174 cites W2160788266 @default.
- W2080431174 cites W2313868127 @default.
- W2080431174 cites W254834723 @default.
- W2080431174 cites W3105389802 @default.
- W2080431174 doi "https://doi.org/10.1212/wnl.53.1.122" @default.
- W2080431174 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10408547" @default.
- W2080431174 hasPublicationYear "1999" @default.
- W2080431174 type Work @default.
- W2080431174 sameAs 2080431174 @default.
- W2080431174 citedByCount "146" @default.
- W2080431174 countsByYear W20804311742012 @default.
- W2080431174 countsByYear W20804311742013 @default.
- W2080431174 countsByYear W20804311742014 @default.
- W2080431174 countsByYear W20804311742015 @default.
- W2080431174 countsByYear W20804311742016 @default.
- W2080431174 countsByYear W20804311742017 @default.
- W2080431174 countsByYear W20804311742018 @default.
- W2080431174 countsByYear W20804311742019 @default.
- W2080431174 countsByYear W20804311742020 @default.
- W2080431174 countsByYear W20804311742021 @default.
- W2080431174 countsByYear W20804311742022 @default.
- W2080431174 countsByYear W20804311742023 @default.
- W2080431174 crossrefType "journal-article" @default.
- W2080431174 hasAuthorship W2080431174A5007298743 @default.
- W2080431174 hasAuthorship W2080431174A5020265434 @default.
- W2080431174 hasAuthorship W2080431174A5029167216 @default.
- W2080431174 hasAuthorship W2080431174A5036176385 @default.
- W2080431174 hasAuthorship W2080431174A5050366628 @default.
- W2080431174 hasAuthorship W2080431174A5057930855 @default.
- W2080431174 hasAuthorship W2080431174A5061154632 @default.
- W2080431174 hasAuthorship W2080431174A5063180827 @default.
- W2080431174 hasConcept C126322002 @default.
- W2080431174 hasConcept C127413603 @default.
- W2080431174 hasConcept C141071460 @default.
- W2080431174 hasConcept C142724271 @default.
- W2080431174 hasConcept C164705383 @default.
- W2080431174 hasConcept C204787440 @default.
- W2080431174 hasConcept C27081682 @default.
- W2080431174 hasConcept C2776268601 @default.
- W2080431174 hasConcept C2777015399 @default.
- W2080431174 hasConcept C2778333808 @default.
- W2080431174 hasConcept C2780007028 @default.
- W2080431174 hasConcept C2780645631 @default.
- W2080431174 hasConcept C71924100 @default.
- W2080431174 hasConcept C78519656 @default.
- W2080431174 hasConceptScore W2080431174C126322002 @default.
- W2080431174 hasConceptScore W2080431174C127413603 @default.
- W2080431174 hasConceptScore W2080431174C141071460 @default.
- W2080431174 hasConceptScore W2080431174C142724271 @default.
- W2080431174 hasConceptScore W2080431174C164705383 @default.
- W2080431174 hasConceptScore W2080431174C204787440 @default.
- W2080431174 hasConceptScore W2080431174C27081682 @default.
- W2080431174 hasConceptScore W2080431174C2776268601 @default.
- W2080431174 hasConceptScore W2080431174C2777015399 @default.
- W2080431174 hasConceptScore W2080431174C2778333808 @default.
- W2080431174 hasConceptScore W2080431174C2780007028 @default.
- W2080431174 hasConceptScore W2080431174C2780645631 @default.
- W2080431174 hasConceptScore W2080431174C71924100 @default.
- W2080431174 hasConceptScore W2080431174C78519656 @default.
- W2080431174 hasIssue "1" @default.
- W2080431174 hasLocation W20804311741 @default.
- W2080431174 hasLocation W20804311742 @default.
- W2080431174 hasOpenAccess W2080431174 @default.
- W2080431174 hasPrimaryLocation W20804311741 @default.
- W2080431174 hasRelatedWork W1946723818 @default.
- W2080431174 hasRelatedWork W1973618900 @default.
- W2080431174 hasRelatedWork W1976398380 @default.
- W2080431174 hasRelatedWork W2005149089 @default.
- W2080431174 hasRelatedWork W2008054374 @default.
- W2080431174 hasRelatedWork W2109170798 @default.
- W2080431174 hasRelatedWork W2136055521 @default.
- W2080431174 hasRelatedWork W2374060430 @default.
- W2080431174 hasRelatedWork W2387330792 @default.
- W2080431174 hasRelatedWork W4200013676 @default.
- W2080431174 hasVolume "53" @default.
- W2080431174 isParatext "false" @default.
- W2080431174 isRetracted "false" @default.
- W2080431174 magId "2080431174" @default.