FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080432829> ?p ?o ?g. }

• W2080432829 endingPage "12" @default.
• W2080432829 startingPage "1" @default.
• W2080432829 abstract "The cytogenetic effect of 2,4-dichlorophenoxy acetic acid (2,4-D) and its metabolite 2,4-dichlorophenol (2,4-DCP) was studied in bone-marrow, germ cells and sperm head abnormalities in the treated mice. Swiss mice were treated orally by gavage with 2,4-D at 1.7, 3.3 and 33 mg kg(-1)BW (1/200, 1/100 and 1/10 of LD(50)). 2,4-DCP was intraperitoneally (i.p.) injected at 36, 72 and 180 mg kg(-1)BW (1/10, 1/5, 1/2 of LD(50)). A significant increase in the percentage of chromosome aberrations in bone-marrow and spermatocyte cells was observed after oral administration of 2,4-D at 3.3 mg kg(-1)BW for three and five consecutive days. This percentage increased and reached 10.8+/-0.87 (P<0.01) in bone-marrow and 9.8+/-0.45 (P<0.01) in spermatocyte cells after oral administration of 2,4-D at 33 mg kg(-1)BW for 24 h. This percentage was, however, lower than that induced in bone-marrow and spermatocyte cells by mitomycin C (positive control). 2,4-D induced a dose-dependent increase in the percentage of sperm head abnormalities. The genotoxic effect of 2,4-DCP is weaker than that of 2,4-D, as indicated by the lower percentage of the induced chromosome aberrations (in bone-marrow and spermatocyte cells) and sperm head abnormalities. Only the highest tested concentration of 2,4-DCP (180 mg kg(-1)BW, 1/2 LD(50)) induced a significant percentage of chromosome aberrations and sperm head abnormalities after i.p. injection. The obtained results indicate that 2,4-D is genotoxic in mice in vivo under the conditions tested. Hence, more care should be given to the application of 2,4-D on edible crops since repeated uses may underlie a health hazard." @default.
• W2080432829 created "2016-06-24" @default.
• W2080432829 creator A5004862927 @default.
• W2080432829 creator A5028320644 @default.
• W2080432829 date "2001-07-01" @default.
• W2080432829 modified "2023-10-16" @default.
• W2080432829 title "Genotoxic effect of 2,4-dichlorophenoxy acetic acid and its metabolite 2,4-dichlorophenol in mouse" @default.
• W2080432829 cites W1580718844 @default.
• W2080432829 cites W1593806668 @default.
• W2080432829 cites W1758868801 @default.
• W2080432829 cites W1977009097 @default.
• W2080432829 cites W2001284199 @default.
• W2080432829 cites W2003717714 @default.
• W2080432829 cites W2007113932 @default.
• W2080432829 cites W2007306633 @default.
• W2080432829 cites W2007911760 @default.
• W2080432829 cites W2008843113 @default.
• W2080432829 cites W2017935725 @default.
• W2080432829 cites W2018437991 @default.
• W2080432829 cites W2019805224 @default.
• W2080432829 cites W2020555657 @default.
• W2080432829 cites W2046853036 @default.
• W2080432829 cites W2070975150 @default.
• W2080432829 cites W2085369890 @default.
• W2080432829 cites W2086076188 @default.
• W2080432829 cites W2088221164 @default.
• W2080432829 cites W2105053821 @default.
• W2080432829 cites W2106268634 @default.
• W2080432829 cites W2130273335 @default.
• W2080432829 cites W2149969121 @default.
• W2080432829 cites W2155690394 @default.
• W2080432829 cites W2511442274 @default.
• W2080432829 cites W2555881333 @default.
• W2080432829 cites W2946386416 @default.
• W2080432829 cites W2198578671 @default.
• W2080432829 doi "https://doi.org/10.1016/s1383-5718(01)00146-2" @default.
• W2080432829 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11423340" @default.
• W2080432829 hasPublicationYear "2001" @default.
• W2080432829 type Work @default.
• W2080432829 sameAs 2080432829 @default.
• W2080432829 citedByCount "74" @default.
• W2080432829 countsByYear W20804328292012 @default.
• W2080432829 countsByYear W20804328292013 @default.
• W2080432829 countsByYear W20804328292014 @default.
• W2080432829 countsByYear W20804328292015 @default.
• W2080432829 countsByYear W20804328292016 @default.
• W2080432829 countsByYear W20804328292017 @default.
• W2080432829 countsByYear W20804328292018 @default.
• W2080432829 countsByYear W20804328292019 @default.
• W2080432829 countsByYear W20804328292020 @default.
• W2080432829 countsByYear W20804328292022 @default.
• W2080432829 countsByYear W20804328292023 @default.
• W2080432829 crossrefType "journal-article" @default.
• W2080432829 hasAuthorship W2080432829A5004862927 @default.
• W2080432829 hasAuthorship W2080432829A5028320644 @default.
• W2080432829 hasConcept C104317684 @default.
• W2080432829 hasConcept C123765429 @default.
• W2080432829 hasConcept C126322002 @default.
• W2080432829 hasConcept C134018914 @default.
• W2080432829 hasConcept C148196450 @default.
• W2080432829 hasConcept C16685009 @default.
• W2080432829 hasConcept C185592680 @default.
• W2080432829 hasConcept C2776053789 @default.
• W2080432829 hasConcept C2777477808 @default.
• W2080432829 hasConcept C2779338040 @default.
• W2080432829 hasConcept C2780007613 @default.
• W2080432829 hasConcept C2781087480 @default.
• W2080432829 hasConcept C54355233 @default.
• W2080432829 hasConcept C55493867 @default.
• W2080432829 hasConcept C71924100 @default.
• W2080432829 hasConcept C86803240 @default.
• W2080432829 hasConceptScore W2080432829C104317684 @default.
• W2080432829 hasConceptScore W2080432829C123765429 @default.
• W2080432829 hasConceptScore W2080432829C126322002 @default.
• W2080432829 hasConceptScore W2080432829C134018914 @default.
• W2080432829 hasConceptScore W2080432829C148196450 @default.
• W2080432829 hasConceptScore W2080432829C16685009 @default.
• W2080432829 hasConceptScore W2080432829C185592680 @default.
• W2080432829 hasConceptScore W2080432829C2776053789 @default.
• W2080432829 hasConceptScore W2080432829C2777477808 @default.
• W2080432829 hasConceptScore W2080432829C2779338040 @default.
• W2080432829 hasConceptScore W2080432829C2780007613 @default.
• W2080432829 hasConceptScore W2080432829C2781087480 @default.
• W2080432829 hasConceptScore W2080432829C54355233 @default.
• W2080432829 hasConceptScore W2080432829C55493867 @default.
• W2080432829 hasConceptScore W2080432829C71924100 @default.
• W2080432829 hasConceptScore W2080432829C86803240 @default.
• W2080432829 hasIssue "1-2" @default.
• W2080432829 hasLocation W20804328291 @default.
• W2080432829 hasLocation W20804328292 @default.
• W2080432829 hasOpenAccess W2080432829 @default.
• W2080432829 hasPrimaryLocation W20804328291 @default.
• W2080432829 hasRelatedWork W1211958720 @default.
• W2080432829 hasRelatedWork W1988486434 @default.
• W2080432829 hasRelatedWork W2010761373 @default.
• W2080432829 hasRelatedWork W2041747613 @default.
• W2080432829 hasRelatedWork W2078197242 @default.
• W2080432829 hasRelatedWork W2143423115 @default.

• next