Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080437679> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2080437679 endingPage "99" @default.
- W2080437679 startingPage "91" @default.
- W2080437679 abstract "A simple and sensitive high-performance liquid chromatographic method has been developed for the quantitative determination of aminopyrine and eight of its metabolites (4-methylaminoantipyrine, 4-aminoantipyrine, 4-acetylaminoantipyrine, 4-acetylmethyl-aminoantipyrine, 4-hydroxyantipyrine, 4-formylaminoantipyrine, 3-hydroxymethyl-2-methyl-4-dimethylamino-1-phenyl-3-pyrazolin-5-one and 2-methyl-4-dimethylamino-5-oxo-1-phenyl-3-pyrazoline-3-carboxylic acid) in plasma of rats. The procedure includes a chloroform extraction prior to chromatography and quantitative analysis using peak-area ratios (ultraviolet absorbance detection at 260 nm) of aminopyrine and its metabolites to the internal standard, phenobarbital. The concentration—response curves for these compounds were linear from 20 ng/ml to 200 μg/ml. The extraction coefficients of aminopyrine and its metabolites from plasma were 80–100%. The coefficients of variation of intra- and inter-assay for these compounds in plasma were less than 2.5–5.5%. This method has been found to be applicable to the analysis of plasma samples obtained from aminopyrine-dosed rats." @default.
- W2080437679 created "2016-06-24" @default.
- W2080437679 creator A5029949387 @default.
- W2080437679 creator A5042820780 @default.
- W2080437679 creator A5070271700 @default.
- W2080437679 date "1986-01-01" @default.
- W2080437679 modified "2023-09-26" @default.
- W2080437679 title "Simultaneous determination of aminopyrine and its metabolites in rat plasma by high-performance liquid chromatography" @default.
- W2080437679 cites W1983427573 @default.
- W2080437679 cites W2258025409 @default.
- W2080437679 cites W2315231370 @default.
- W2080437679 cites W2318463887 @default.
- W2080437679 cites W2318779754 @default.
- W2080437679 cites W2328775842 @default.
- W2080437679 cites W2329423916 @default.
- W2080437679 cites W2330778149 @default.
- W2080437679 cites W2342291911 @default.
- W2080437679 cites W2412201064 @default.
- W2080437679 cites W2412327223 @default.
- W2080437679 cites W2414777385 @default.
- W2080437679 cites W2432617560 @default.
- W2080437679 cites W2466251731 @default.
- W2080437679 cites W3193395198 @default.
- W2080437679 cites W2050239605 @default.
- W2080437679 doi "https://doi.org/10.1016/s0378-4347(00)83695-6" @default.
- W2080437679 hasPublicationYear "1986" @default.
- W2080437679 type Work @default.
- W2080437679 sameAs 2080437679 @default.
- W2080437679 citedByCount "3" @default.
- W2080437679 crossrefType "journal-article" @default.
- W2080437679 hasAuthorship W2080437679A5029949387 @default.
- W2080437679 hasAuthorship W2080437679A5042820780 @default.
- W2080437679 hasAuthorship W2080437679A5070271700 @default.
- W2080437679 hasConcept C178790620 @default.
- W2080437679 hasConcept C179998833 @default.
- W2080437679 hasConcept C185592680 @default.
- W2080437679 hasConcept C2777477808 @default.
- W2080437679 hasConcept C2780591741 @default.
- W2080437679 hasConcept C2781144210 @default.
- W2080437679 hasConcept C43617362 @default.
- W2080437679 hasConcept C4725764 @default.
- W2080437679 hasConcept C55493867 @default.
- W2080437679 hasConcept C95986675 @default.
- W2080437679 hasConcept C98015330 @default.
- W2080437679 hasConceptScore W2080437679C178790620 @default.
- W2080437679 hasConceptScore W2080437679C179998833 @default.
- W2080437679 hasConceptScore W2080437679C185592680 @default.
- W2080437679 hasConceptScore W2080437679C2777477808 @default.
- W2080437679 hasConceptScore W2080437679C2780591741 @default.
- W2080437679 hasConceptScore W2080437679C2781144210 @default.
- W2080437679 hasConceptScore W2080437679C43617362 @default.
- W2080437679 hasConceptScore W2080437679C4725764 @default.
- W2080437679 hasConceptScore W2080437679C55493867 @default.
- W2080437679 hasConceptScore W2080437679C95986675 @default.
- W2080437679 hasConceptScore W2080437679C98015330 @default.
- W2080437679 hasLocation W20804376791 @default.
- W2080437679 hasOpenAccess W2080437679 @default.
- W2080437679 hasPrimaryLocation W20804376791 @default.
- W2080437679 hasRelatedWork W1601382037 @default.
- W2080437679 hasRelatedWork W1963854375 @default.
- W2080437679 hasRelatedWork W1973892552 @default.
- W2080437679 hasRelatedWork W1999301148 @default.
- W2080437679 hasRelatedWork W2005883348 @default.
- W2080437679 hasRelatedWork W2107750257 @default.
- W2080437679 hasRelatedWork W2124457351 @default.
- W2080437679 hasRelatedWork W2150718626 @default.
- W2080437679 hasRelatedWork W2314202589 @default.
- W2080437679 hasRelatedWork W2418246579 @default.
- W2080437679 hasVolume "375" @default.
- W2080437679 isParatext "false" @default.
- W2080437679 isRetracted "false" @default.
- W2080437679 magId "2080437679" @default.
- W2080437679 workType "article" @default.