FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080442603> ?p ?o ?g. }

• W2080442603 endingPage "297" @default.
• W2080442603 startingPage "291" @default.
• W2080442603 abstract "An endophytic Cryptosporiopsis sp. was isolated from Clidemia hirta and analyzed for its secondary metabolites that lead to the isolation of three bioactive molecules. The compounds were purified from the culture broth of the fungus and their structures were determined by spectroscopic methods as (R)-5-hydroxy-2-methylchroman-4-one (1), 1-(2,6-dihydroxyphenyl)pentan-1-one (2) and (Z)-1-(2-(2-butyryl-3-hydroxyphenoxy)-6-hydroxyphenyl)-3-hydroxybut-2-en-1-one (3). Compound 1 exhibited significant cytotoxic activity against the human leukemia cell line, HL-60 with an IC50 of 4 μg/ml. This compound induced G2 arrest of the HL-60 cell cycle significantly. In addition, out of these compounds, 2 and 3 were active against several bacterial pathogens. Compound 2 was active against Bacillus cereus, Escherichia coli and Staphylococcus aureus with IC50 values varying from 18 to 30 μg/ml, and compound 3 displayed activity against Pseudomonas fluorescens with an IC50 value of 6 μg/ml. Compounds 2 and 3 are novel whereas compound 1 was reported earlier but the stereochemistry of its C-2 methyl is established for the first time." @default.
• W2080442603 created "2016-06-24" @default.
• W2080442603 creator A5002636758 @default.
• W2080442603 creator A5010392796 @default.
• W2080442603 creator A5015496866 @default.
• W2080442603 creator A5017888013 @default.
• W2080442603 creator A5023099379 @default.
• W2080442603 creator A5026567455 @default.
• W2080442603 creator A5046268716 @default.
• W2080442603 creator A5056177485 @default.
• W2080442603 creator A5063621367 @default.
• W2080442603 creator A5065297081 @default.
• W2080442603 creator A5075526042 @default.
• W2080442603 creator A5087616711 @default.
• W2080442603 date "2013-11-01" @default.
• W2080442603 modified "2023-10-16" @default.
• W2080442603 title "Bioactive metabolites from an endophytic Cryptosporiopsis sp. inhabiting Clidemia hirta" @default.
• W2080442603 cites W1963648227 @default.
• W2080442603 cites W1967101669 @default.
• W2080442603 cites W1978850709 @default.
• W2080442603 cites W1990693572 @default.
• W2080442603 cites W2003226432 @default.
• W2080442603 cites W2012170494 @default.
• W2080442603 cites W2012899054 @default.
• W2080442603 cites W2015884448 @default.
• W2080442603 cites W2016294835 @default.
• W2080442603 cites W2026029578 @default.
• W2080442603 cites W2029979826 @default.
• W2080442603 cites W2037594947 @default.
• W2080442603 cites W2040228452 @default.
• W2080442603 cites W2040460662 @default.
• W2080442603 cites W2045265255 @default.
• W2080442603 cites W2049434620 @default.
• W2080442603 cites W2053481791 @default.
• W2080442603 cites W2075843047 @default.
• W2080442603 cites W2077839976 @default.
• W2080442603 cites W2093383037 @default.
• W2080442603 cites W2098151907 @default.
• W2080442603 cites W2125121305 @default.
• W2080442603 cites W2129547556 @default.
• W2080442603 cites W2131897196 @default.
• W2080442603 cites W2137980120 @default.
• W2080442603 cites W2146691651 @default.
• W2080442603 cites W2158714788 @default.
• W2080442603 doi "https://doi.org/10.1016/j.phytochem.2013.06.021" @default.
• W2080442603 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23870821" @default.
• W2080442603 hasPublicationYear "2013" @default.
• W2080442603 type Work @default.
• W2080442603 sameAs 2080442603 @default.
• W2080442603 citedByCount "46" @default.
• W2080442603 countsByYear W20804426032014 @default.
• W2080442603 countsByYear W20804426032015 @default.
• W2080442603 countsByYear W20804426032016 @default.
• W2080442603 countsByYear W20804426032017 @default.
• W2080442603 countsByYear W20804426032018 @default.
• W2080442603 countsByYear W20804426032019 @default.
• W2080442603 countsByYear W20804426032020 @default.
• W2080442603 countsByYear W20804426032021 @default.
• W2080442603 countsByYear W20804426032022 @default.
• W2080442603 countsByYear W20804426032023 @default.
• W2080442603 crossrefType "journal-article" @default.
• W2080442603 hasAuthorship W2080442603A5002636758 @default.
• W2080442603 hasAuthorship W2080442603A5010392796 @default.
• W2080442603 hasAuthorship W2080442603A5015496866 @default.
• W2080442603 hasAuthorship W2080442603A5017888013 @default.
• W2080442603 hasAuthorship W2080442603A5023099379 @default.
• W2080442603 hasAuthorship W2080442603A5026567455 @default.
• W2080442603 hasAuthorship W2080442603A5046268716 @default.
• W2080442603 hasAuthorship W2080442603A5056177485 @default.
• W2080442603 hasAuthorship W2080442603A5063621367 @default.
• W2080442603 hasAuthorship W2080442603A5065297081 @default.
• W2080442603 hasAuthorship W2080442603A5075526042 @default.
• W2080442603 hasAuthorship W2080442603A5087616711 @default.
• W2080442603 hasBestOaLocation W20804426032 @default.
• W2080442603 hasConcept C104317684 @default.
• W2080442603 hasConcept C185592680 @default.
• W2080442603 hasConcept C202751555 @default.
• W2080442603 hasConcept C2776835041 @default.
• W2080442603 hasConcept C2777118263 @default.
• W2080442603 hasConcept C2777752497 @default.
• W2080442603 hasConcept C2779489039 @default.
• W2080442603 hasConcept C2780373777 @default.
• W2080442603 hasConcept C523546767 @default.
• W2080442603 hasConcept C54355233 @default.
• W2080442603 hasConcept C547475151 @default.
• W2080442603 hasConcept C55493867 @default.
• W2080442603 hasConcept C59822182 @default.
• W2080442603 hasConcept C71240020 @default.
• W2080442603 hasConcept C86803240 @default.
• W2080442603 hasConcept C89423630 @default.
• W2080442603 hasConcept C89638049 @default.
• W2080442603 hasConceptScore W2080442603C104317684 @default.
• W2080442603 hasConceptScore W2080442603C185592680 @default.
• W2080442603 hasConceptScore W2080442603C202751555 @default.
• W2080442603 hasConceptScore W2080442603C2776835041 @default.
• W2080442603 hasConceptScore W2080442603C2777118263 @default.
• W2080442603 hasConceptScore W2080442603C2777752497 @default.
• W2080442603 hasConceptScore W2080442603C2779489039 @default.

• next