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- W2080454547 abstract "Protein-energy malnutrition (PEM) is a serious nutritional problem in hospitalized elderly patients. Serum albumin, transthyretin (prealbumin), and total protein have been used as biochemical indicators of protein nutritional status, but taking blood from the elderly is difficult and invasive. We therefore assessed the possibility of using saliva or urine as noninvasive materials to estimate serum concentrations of albumin, transthyretin and total protein. Blood, saliva and urine were collected from 32 hospitalized elderly (aged 68–97 y) and the correlation between the concentrations of albumin, transthyretin and total protein in serum and those in saliva or urine were evaluated. There was no correlation among them, but the concentrations of albumin and transthyretin adjusted for the concentration of IgG in saliva were significantly correlated with the concentrations of albumin and transthyretin in serum (albumin: R2 = 0.308, p = 0.0010, transthyretin: R2 = 0.433, p < 0.001 by log linear regression analysis). This study suggests the possible usefulness of the concentrations of proteins in the fluids for evaluating protein nutritional status in the elderly. Further studies on the method of adjustment of protein concentrations in saliva and the adaptability to other populations will confirm the results of this study." @default.
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- W2080454547 title "Salivary indicators of protein nutritional status in the elderly" @default.
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- W2080454547 doi "https://doi.org/10.1016/s0271-5317(99)00058-5" @default.
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