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- W2080454718 endingPage "16912" @default.
- W2080454718 startingPage "16912" @default.
- W2080454718 abstract "Markov (state) models (MSMs) have attracted a lot of interest recently as they (1) can probe long-term molecular kinetics based on short-time simulations, (2) offer a way to analyze great amounts of simulation data with relatively little subjectivity of the analyst, (3) provide insight into microscopic quantities such as the ensemble of transition pathways, and (4) allow simulation data to be reconciled with measurement data in a rigorous and explicit way. Here we sketch our current perspective of Markov models and explain in short their theoretical basis and assumptions. We describe transition path theory which allows the entire ensemble of protein folding pathways to be investigated and that combines naturally with Markov models. Experimental observations can be naturally linked to Markov models with the dynamical fingerprint theory, by which experimentally observable timescales can be equipped with an understanding of the structural rearrangement processes that take place at these timescales. The concepts of this paper are illustrated by a simple kinetic model of protein folding." @default.
- W2080454718 created "2016-06-24" @default.
- W2080454718 creator A5003354271 @default.
- W2080454718 creator A5038990214 @default.
- W2080454718 creator A5055016850 @default.
- W2080454718 date "2011-01-01" @default.
- W2080454718 modified "2023-09-30" @default.
- W2080454718 title "Probing molecular kinetics with Markov models: metastable states, transition pathways and spectroscopic observables" @default.
- W2080454718 cites W1505478715 @default.
- W2080454718 cites W1967657900 @default.
- W2080454718 cites W1967722756 @default.
- W2080454718 cites W1969903391 @default.
- W2080454718 cites W1970440715 @default.
- W2080454718 cites W1970580210 @default.
- W2080454718 cites W1971832114 @default.
- W2080454718 cites W1974071773 @default.
- W2080454718 cites W1975006627 @default.
- W2080454718 cites W1977179882 @default.
- W2080454718 cites W1977969550 @default.
- W2080454718 cites W1979070806 @default.
- W2080454718 cites W1980055293 @default.
- W2080454718 cites W1985277612 @default.
- W2080454718 cites W1986155795 @default.
- W2080454718 cites W1987887771 @default.
- W2080454718 cites W1988220126 @default.
- W2080454718 cites W1989451710 @default.
- W2080454718 cites W1990593157 @default.
- W2080454718 cites W1991745348 @default.
- W2080454718 cites W1992924464 @default.
- W2080454718 cites W1993542065 @default.
- W2080454718 cites W1997466811 @default.
- W2080454718 cites W2001286319 @default.
- W2080454718 cites W2007778981 @default.
- W2080454718 cites W2013371652 @default.
- W2080454718 cites W2014095962 @default.
- W2080454718 cites W2014461019 @default.
- W2080454718 cites W2016885268 @default.
- W2080454718 cites W2017896410 @default.
- W2080454718 cites W2018097663 @default.
- W2080454718 cites W2021541427 @default.
- W2080454718 cites W2025899185 @default.
- W2080454718 cites W2029137764 @default.
- W2080454718 cites W2029564559 @default.
- W2080454718 cites W2031843459 @default.
- W2080454718 cites W2034601153 @default.
- W2080454718 cites W2040517336 @default.
- W2080454718 cites W2041721370 @default.
- W2080454718 cites W2044201287 @default.
- W2080454718 cites W2046002103 @default.
- W2080454718 cites W2046290306 @default.
- W2080454718 cites W2046337401 @default.
- W2080454718 cites W2047348666 @default.
- W2080454718 cites W2052846767 @default.
- W2080454718 cites W2055484248 @default.
- W2080454718 cites W2055827177 @default.
- W2080454718 cites W2056859449 @default.
- W2080454718 cites W2059187210 @default.
- W2080454718 cites W2061342938 @default.
- W2080454718 cites W2062421175 @default.
- W2080454718 cites W2072290134 @default.
- W2080454718 cites W2075349828 @default.
- W2080454718 cites W2075460992 @default.
- W2080454718 cites W2076289581 @default.
- W2080454718 cites W2076441421 @default.
- W2080454718 cites W2076473013 @default.
- W2080454718 cites W2076867795 @default.
- W2080454718 cites W2082299213 @default.
- W2080454718 cites W2085213650 @default.
- W2080454718 cites W2086193487 @default.
- W2080454718 cites W2088139266 @default.
- W2080454718 cites W2088647884 @default.
- W2080454718 cites W2088941628 @default.
- W2080454718 cites W2089954482 @default.
- W2080454718 cites W2091707670 @default.
- W2080454718 cites W2094795801 @default.
- W2080454718 cites W2095352365 @default.
- W2080454718 cites W2098834046 @default.
- W2080454718 cites W2099490136 @default.
- W2080454718 cites W2103014607 @default.
- W2080454718 cites W2105880172 @default.
- W2080454718 cites W2111339528 @default.
- W2080454718 cites W2120595908 @default.
- W2080454718 cites W2123132657 @default.
- W2080454718 cites W2129020329 @default.
- W2080454718 cites W2132589721 @default.
- W2080454718 cites W2138070139 @default.
- W2080454718 cites W2140797130 @default.
- W2080454718 cites W2141796022 @default.
- W2080454718 cites W2144729032 @default.
- W2080454718 cites W2144916347 @default.
- W2080454718 cites W2148494031 @default.
- W2080454718 cites W2155756597 @default.
- W2080454718 cites W2165890129 @default.
- W2080454718 cites W2170735789 @default.
- W2080454718 doi "https://doi.org/10.1039/c1cp21258c" @default.
- W2080454718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21858310" @default.
- W2080454718 hasPublicationYear "2011" @default.
- W2080454718 type Work @default.