FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080455954> ?p ?o ?g. }

• W2080455954 endingPage "3682" @default.
• W2080455954 startingPage "3675" @default.
• W2080455954 abstract "Basophils are increasingly recognized as playing important roles in the immune response toward helminths. In this study, we evaluated the role of basophils in vaccine-mediated protection against filariae, tissue-invasive parasitic nematodes responsible for diseases such as elephantiasis and river blindness. Protective immunity and immunological responses were assessed in BALB/c mice vaccinated with irradiated L3 stage larvae and depleted of basophils with weekly injections of anti-CD200R3 antibody. Depletion of basophils after administration of the vaccination regimen but before challenge infection did not alter protective immunity. In contrast, basophil depletion initiated prior to vaccination and continued after challenge infection significantly attenuated the protective effect conferred by vaccination. Vaccine-induced cellular immune responses to parasite antigen were substantially decreased in basophil-depleted mice, with significant decreases in CD4(+) T-cell production of IL-4, IL-5, IL-10, and IFN-γ. Interestingly, skin mast cell numbers, which increased significantly after vaccination with irradiated L3 larvae, were unchanged after vaccination in basophil-depleted mice. These findings demonstrate that basophils help establish the immune responses responsible for irradiated L3 vaccine protection." @default.
• W2080455954 created "2016-06-24" @default.
• W2080455954 creator A5003351346 @default.
• W2080455954 creator A5018022957 @default.
• W2080455954 creator A5020458885 @default.
• W2080455954 creator A5033576692 @default.
• W2080455954 creator A5040756646 @default.
• W2080455954 creator A5042049581 @default.
• W2080455954 creator A5088404286 @default.
• W2080455954 date "2013-08-01" @default.
• W2080455954 modified "2023-10-13" @default.
• W2080455954 title "Basophils help establish protective immunity induced by irradiated larval vaccination for filariasis" @default.
• W2080455954 cites W1490525966 @default.
• W2080455954 cites W1530482090 @default.
• W2080455954 cites W1552035119 @default.
• W2080455954 cites W1560419085 @default.
• W2080455954 cites W1833667645 @default.
• W2080455954 cites W186058086 @default.
• W2080455954 cites W1980421217 @default.
• W2080455954 cites W1996283702 @default.
• W2080455954 cites W2000301541 @default.
• W2080455954 cites W2001912237 @default.
• W2080455954 cites W2002626580 @default.
• W2080455954 cites W2005869477 @default.
• W2080455954 cites W2007125922 @default.
• W2080455954 cites W2011600307 @default.
• W2080455954 cites W2024158949 @default.
• W2080455954 cites W2041156669 @default.
• W2080455954 cites W2068897171 @default.
• W2080455954 cites W2070267552 @default.
• W2080455954 cites W2071224362 @default.
• W2080455954 cites W2076635129 @default.
• W2080455954 cites W2079854540 @default.
• W2080455954 cites W2092691391 @default.
• W2080455954 cites W2094245714 @default.
• W2080455954 cites W210228093 @default.
• W2080455954 cites W2111075482 @default.
• W2080455954 cites W2111569297 @default.
• W2080455954 cites W2113703271 @default.
• W2080455954 cites W2123760021 @default.
• W2080455954 cites W2137425057 @default.
• W2080455954 cites W2145926064 @default.
• W2080455954 cites W2156690909 @default.
• W2080455954 cites W2162855309 @default.
• W2080455954 cites W2169143731 @default.
• W2080455954 doi "https://doi.org/10.1016/j.vaccine.2013.06.010" @default.
• W2080455954 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3733094" @default.
• W2080455954 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23777951" @default.
• W2080455954 hasPublicationYear "2013" @default.
• W2080455954 type Work @default.
• W2080455954 sameAs 2080455954 @default.
• W2080455954 citedByCount "15" @default.
• W2080455954 countsByYear W20804559542014 @default.
• W2080455954 countsByYear W20804559542015 @default.
• W2080455954 countsByYear W20804559542016 @default.
• W2080455954 countsByYear W20804559542017 @default.
• W2080455954 countsByYear W20804559542018 @default.
• W2080455954 countsByYear W20804559542020 @default.
• W2080455954 countsByYear W20804559542021 @default.
• W2080455954 countsByYear W20804559542023 @default.
• W2080455954 crossrefType "journal-article" @default.
• W2080455954 hasAuthorship W2080455954A5003351346 @default.
• W2080455954 hasAuthorship W2080455954A5018022957 @default.
• W2080455954 hasAuthorship W2080455954A5020458885 @default.
• W2080455954 hasAuthorship W2080455954A5033576692 @default.
• W2080455954 hasAuthorship W2080455954A5040756646 @default.
• W2080455954 hasAuthorship W2080455954A5042049581 @default.
• W2080455954 hasAuthorship W2080455954A5088404286 @default.
• W2080455954 hasBestOaLocation W20804559542 @default.
• W2080455954 hasConcept C203014093 @default.
• W2080455954 hasConcept C22070199 @default.
• W2080455954 hasConcept C2779341262 @default.
• W2080455954 hasConcept C86803240 @default.
• W2080455954 hasConcept C8891405 @default.
• W2080455954 hasConceptScore W2080455954C203014093 @default.
• W2080455954 hasConceptScore W2080455954C22070199 @default.
• W2080455954 hasConceptScore W2080455954C2779341262 @default.
• W2080455954 hasConceptScore W2080455954C86803240 @default.
• W2080455954 hasConceptScore W2080455954C8891405 @default.
• W2080455954 hasIssue "36" @default.
• W2080455954 hasLocation W20804559541 @default.
• W2080455954 hasLocation W20804559542 @default.
• W2080455954 hasLocation W20804559543 @default.
• W2080455954 hasLocation W20804559544 @default.
• W2080455954 hasOpenAccess W2080455954 @default.
• W2080455954 hasPrimaryLocation W20804559541 @default.
• W2080455954 hasRelatedWork W1641042124 @default.
• W2080455954 hasRelatedWork W1990804418 @default.
• W2080455954 hasRelatedWork W1993764875 @default.
• W2080455954 hasRelatedWork W2013243191 @default.
• W2080455954 hasRelatedWork W2051339581 @default.
• W2080455954 hasRelatedWork W2082860237 @default.
• W2080455954 hasRelatedWork W2117258802 @default.
• W2080455954 hasRelatedWork W2130076355 @default.
• W2080455954 hasRelatedWork W2151865869 @default.
• W2080455954 hasRelatedWork W2570867257 @default.
• W2080455954 hasVolume "31" @default.
• W2080455954 isParatext "false" @default.

• next