Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080461503> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2080461503 endingPage "361" @default.
- W2080461503 startingPage "361" @default.
- W2080461503 abstract "Mol Syst Biol. 6: 361Genome‐scale metabolic network reconstructions represent biochemical, genetic, and genomic (BiGG) knowledge bases for a target organism (Reed et al , 2006). Thus, they correspond to two‐dimensional genome annotations: that is, they contain all nodes and links that comprise a biochemical reaction network defined by the genome (Palsson, 2004). These reconstructions allow the conversion of biological knowledge into a mathematical format and subsequent computation of physiological properties. They therefore enable the formulation of a mechanistic genotype–phenotype relationship for metabolic functions in the target organism.The metabolic network reconstruction process is now well established (Thiele and Palsson, 2010) and its workflows have recently been reviewed (Reed et al , 2006; Feist et al , 2009). The development of a consensus network reconstruction that is accepted and used by the research community necessitates a collective effort to formalize such networks that are specific to a target organism. This need has led to the concept of a 2D annotation (or a reconstruction) jamboree (Mo and Palsson, 2009), in analogy to the 1D genome annotation jamborees that lead to a community‐driven genome annotation process. You may be interested in organizing a jamboree for your favorite target organism. What do you need to do?The goal of a network reconstruction jamboree is to reconcile and refine currently available BiGG knowledge about the target organism. If available, multiple existing metabolic network reconstructions made by individual research groups provide a great starting point. A jamboree should update, re‐evaluate, refine and, later on, expand the network content. These goals are most efficiently achieved through a community approach that assembles experts from different areas.Jamborees assist in fostering collaborations as well as informing the community about the properties, content, and capabilities of the consensus reconstruction to ensure its broad use for biological, biomedical, …" @default.
- W2080461503 created "2016-06-24" @default.
- W2080461503 creator A5015328710 @default.
- W2080461503 creator A5074725115 @default.
- W2080461503 date "2010-01-01" @default.
- W2080461503 modified "2023-10-14" @default.
- W2080461503 title "Reconstruction annotation jamborees: a community approach to systems biology" @default.
- W2080461503 cites W1975147762 @default.
- W2080461503 cites W1992991604 @default.
- W2080461503 cites W2009940763 @default.
- W2080461503 cites W2047632644 @default.
- W2080461503 cites W2070787626 @default.
- W2080461503 cites W2080211619 @default.
- W2080461503 cites W2085993965 @default.
- W2080461503 cites W2158440231 @default.
- W2080461503 cites W2170427655 @default.
- W2080461503 doi "https://doi.org/10.1038/msb.2010.15" @default.
- W2080461503 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2872611" @default.
- W2080461503 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20393581" @default.
- W2080461503 hasPublicationYear "2010" @default.
- W2080461503 type Work @default.
- W2080461503 sameAs 2080461503 @default.
- W2080461503 citedByCount "58" @default.
- W2080461503 countsByYear W20804615032012 @default.
- W2080461503 countsByYear W20804615032013 @default.
- W2080461503 countsByYear W20804615032014 @default.
- W2080461503 countsByYear W20804615032015 @default.
- W2080461503 countsByYear W20804615032016 @default.
- W2080461503 countsByYear W20804615032017 @default.
- W2080461503 countsByYear W20804615032018 @default.
- W2080461503 countsByYear W20804615032020 @default.
- W2080461503 countsByYear W20804615032021 @default.
- W2080461503 countsByYear W20804615032022 @default.
- W2080461503 countsByYear W20804615032023 @default.
- W2080461503 crossrefType "journal-article" @default.
- W2080461503 hasAuthorship W2080461503A5015328710 @default.
- W2080461503 hasAuthorship W2080461503A5074725115 @default.
- W2080461503 hasBestOaLocation W20804615032 @default.
- W2080461503 hasConcept C152662350 @default.
- W2080461503 hasConcept C2776321320 @default.
- W2080461503 hasConcept C54355233 @default.
- W2080461503 hasConcept C70721500 @default.
- W2080461503 hasConcept C78458016 @default.
- W2080461503 hasConcept C86803240 @default.
- W2080461503 hasConceptScore W2080461503C152662350 @default.
- W2080461503 hasConceptScore W2080461503C2776321320 @default.
- W2080461503 hasConceptScore W2080461503C54355233 @default.
- W2080461503 hasConceptScore W2080461503C70721500 @default.
- W2080461503 hasConceptScore W2080461503C78458016 @default.
- W2080461503 hasConceptScore W2080461503C86803240 @default.
- W2080461503 hasIssue "1" @default.
- W2080461503 hasLocation W20804615031 @default.
- W2080461503 hasLocation W20804615032 @default.
- W2080461503 hasLocation W20804615033 @default.
- W2080461503 hasLocation W20804615034 @default.
- W2080461503 hasLocation W20804615035 @default.
- W2080461503 hasOpenAccess W2080461503 @default.
- W2080461503 hasPrimaryLocation W20804615031 @default.
- W2080461503 hasRelatedWork W1828955125 @default.
- W2080461503 hasRelatedWork W2034736453 @default.
- W2080461503 hasRelatedWork W2044499740 @default.
- W2080461503 hasRelatedWork W2061542922 @default.
- W2080461503 hasRelatedWork W2095471526 @default.
- W2080461503 hasRelatedWork W2190176143 @default.
- W2080461503 hasRelatedWork W2979844864 @default.
- W2080461503 hasRelatedWork W3048727301 @default.
- W2080461503 hasRelatedWork W4246963252 @default.
- W2080461503 hasRelatedWork W4308449887 @default.
- W2080461503 hasVolume "6" @default.
- W2080461503 isParatext "false" @default.
- W2080461503 isRetracted "false" @default.
- W2080461503 magId "2080461503" @default.
- W2080461503 workType "article" @default.