FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080462767> ?p ?o ?g. }

• W2080462767 abstract "Prognostic parameters for axillary node-negative (ANN) breast cancer are still rare. Our aim was to establish potential markers that predict distant metastasis in ANN breast carcinoma and permit detection of the patients with high metastasis risk. A case control study was designed that comprised 64 ANN patients who developed distant metastasis during a 5-10 year follow-up period, 64 ANN patients with recurrence-free survival and 64 node-positive (ANP) comparitors. Immunohistochemistry and/or in situ hybridization were used to detect nm23, Cathepsin-D (Cath-D), Epidermal Growth Factor Receptor (EGFR) and Laminin Receptor (LR) in 192 cases. A significantly lower expression of both nm23 mRNA and protein was found in the ANN-group with poor prognosis compared with the ANN-group with good prognosis (p < 0.01). The protein levels of Cath-D, EGFR and LR were significantly higher in the ANN-group with poor prognosis and in the ANP-group compared with the ANN-group with good prognosis (p < 0.01 or p < 0.05), but no differences were found between the poor ANN-group and the ANP-group. Multiple regression analysis showed a close correlation of nm23, Cath-D and EGFR expression with occurrence of distant metastasis of ANN breast carcinoma. All markers except nm23 correlated with conventional histopathologic criteria such as tumor grade, margin and vessel invasion. The results suggest the combined detection of nm23, Cath-D and EGFR as predictive markers of distant metastasis in ANN breast cancer patients. Quantitative analysis together with clinicopathologic factors could contribute to estimate the potential risk of metastasis and select individual therapy regimen." @default.
• W2080462767 created "2016-06-24" @default.
• W2080462767 creator A5015794731 @default.
• W2080462767 creator A5018863416 @default.
• W2080462767 creator A5029095207 @default.
• W2080462767 creator A5066862050 @default.
• W2080462767 creator A5084234469 @default.
• W2080462767 date "2002-03-15" @default.
• W2080462767 modified "2023-10-16" @default.
• W2080462767 title "Potential markers predicting distant metastasis in axillary node-negative breast carcinoma" @default.
• W2080462767 cites W1757030565 @default.
• W2080462767 cites W1817657028 @default.
• W2080462767 cites W1909781489 @default.
• W2080462767 cites W1963579325 @default.
• W2080462767 cites W1964108360 @default.
• W2080462767 cites W1974274579 @default.
• W2080462767 cites W1977515535 @default.
• W2080462767 cites W1978173438 @default.
• W2080462767 cites W1984685571 @default.
• W2080462767 cites W1985347762 @default.
• W2080462767 cites W1986916340 @default.
• W2080462767 cites W1991235782 @default.
• W2080462767 cites W1996714719 @default.
• W2080462767 cites W1997306755 @default.
• W2080462767 cites W2003692285 @default.
• W2080462767 cites W2003754741 @default.
• W2080462767 cites W2006365806 @default.
• W2080462767 cites W2007599495 @default.
• W2080462767 cites W2007641951 @default.
• W2080462767 cites W2010535170 @default.
• W2080462767 cites W2013212397 @default.
• W2080462767 cites W2018580004 @default.
• W2080462767 cites W2019498266 @default.
• W2080462767 cites W2020413441 @default.
• W2080462767 cites W2020494463 @default.
• W2080462767 cites W2029268691 @default.
• W2080462767 cites W2030605936 @default.
• W2080462767 cites W2032694952 @default.
• W2080462767 cites W2039527032 @default.
• W2080462767 cites W2041881052 @default.
• W2080462767 cites W2047558750 @default.
• W2080462767 cites W2047861359 @default.
• W2080462767 cites W2049236625 @default.
• W2080462767 cites W2057758746 @default.
• W2080462767 cites W2060755116 @default.
• W2080462767 cites W2062819976 @default.
• W2080462767 cites W2063030542 @default.
• W2080462767 cites W2079236887 @default.
• W2080462767 cites W2080177905 @default.
• W2080462767 cites W2084416246 @default.
• W2080462767 cites W2085910666 @default.
• W2080462767 cites W2088594395 @default.
• W2080462767 cites W2092401588 @default.
• W2080462767 cites W2105251884 @default.
• W2080462767 cites W2108479296 @default.
• W2080462767 cites W2116816138 @default.
• W2080462767 cites W2117889583 @default.
• W2080462767 cites W2127088710 @default.
• W2080462767 cites W2135019338 @default.
• W2080462767 cites W2320066500 @default.
• W2080462767 cites W2604190323 @default.
• W2080462767 cites W4245339498 @default.
• W2080462767 doi "https://doi.org/10.1002/ijc.10136" @default.
• W2080462767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11920647" @default.
• W2080462767 hasPublicationYear "2002" @default.
• W2080462767 type Work @default.
• W2080462767 sameAs 2080462767 @default.
• W2080462767 citedByCount "28" @default.
• W2080462767 countsByYear W20804627672014 @default.
• W2080462767 countsByYear W20804627672017 @default.
• W2080462767 countsByYear W20804627672019 @default.
• W2080462767 countsByYear W20804627672020 @default.
• W2080462767 crossrefType "journal-article" @default.
• W2080462767 hasAuthorship W2080462767A5015794731 @default.
• W2080462767 hasAuthorship W2080462767A5018863416 @default.
• W2080462767 hasAuthorship W2080462767A5029095207 @default.
• W2080462767 hasAuthorship W2080462767A5066862050 @default.
• W2080462767 hasAuthorship W2080462767A5084234469 @default.
• W2080462767 hasBestOaLocation W20804627671 @default.
• W2080462767 hasConcept C121608353 @default.
• W2080462767 hasConcept C126322002 @default.
• W2080462767 hasConcept C142724271 @default.
• W2080462767 hasConcept C143998085 @default.
• W2080462767 hasConcept C173633252 @default.
• W2080462767 hasConcept C181199279 @default.
• W2080462767 hasConcept C204232928 @default.
• W2080462767 hasConcept C2779013556 @default.
• W2080462767 hasConcept C3018521938 @default.
• W2080462767 hasConcept C530470458 @default.
• W2080462767 hasConcept C55493867 @default.
• W2080462767 hasConcept C71924100 @default.
• W2080462767 hasConcept C86803240 @default.
• W2080462767 hasConceptScore W2080462767C121608353 @default.
• W2080462767 hasConceptScore W2080462767C126322002 @default.
• W2080462767 hasConceptScore W2080462767C142724271 @default.
• W2080462767 hasConceptScore W2080462767C143998085 @default.
• W2080462767 hasConceptScore W2080462767C173633252 @default.
• W2080462767 hasConceptScore W2080462767C181199279 @default.
• W2080462767 hasConceptScore W2080462767C204232928 @default.
• W2080462767 hasConceptScore W2080462767C2779013556 @default.

• next