FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080462862> ?p ?o ?g. }

• W2080462862 endingPage "13" @default.
• W2080462862 startingPage "7" @default.
• W2080462862 abstract "We investigated a method for the simultaneous screening, identification, and quantitative determination of salicylic acid, acetaminophen, theophylline, barbiturates, and bromvalerylurea, drugs that frequently cause acute poisoning in Japan and therefore require rapid analysis for effective treatment in the clinical setting. The method employs liquid chromatography/electrospray mass spectrometry (LC/MS) of solid-phase extracted serum samples. For LC/MS ionization, the electrospray-ionization method was used, with acetaminophen in the positive-ion mode, and salicylic acid, theophylline, phenobarbital, bromvalerylurea, pentobarbital, amobarbital, and o-acetamidophenol (internal standard) in the negative-ion mode, the base ions were used in each case for quantitative analysis. Quantitation was possible for the following sample concentration ranges: salicylic acid and acetaminophen, 100 to 5 microg/ml; theophylline, 100 to 0.5 microg/ml; and phenobarbital, bromvalerylurea, pentobarbital, and amobarbital, 100 to 1 microg/ml. Using full-scan mass spectrometry, the lower detection limits of 1 microg/ml for salicylic acid and acetaminophen, 0.1 microg/ml for theophylline, and 0.5 microg/ml for phenobarbital, bromvalerylurea, pentobarbital, and amobarbital were adequate for identifying acute poisoning. When each compound was added to serum to a final concentration of 5 microg/ml and solid-phase extraction was performed using Oasis HLB 1-cc (30-mg), the mean recovery rate of each compound was 89.2 to 96.1% (n=5), and the coefficients of variation of the intraday and interday assays were 3.55 to 6.05% (n=5) and 3.68 to 6.38% (n=5), respectively, which are acceptable. When this method of analysis was applied in testing the sera of a female patient who had consumed a large amount of an unknown commercial drug, salicylic acid and bromvalerylurea were identified, and the treatment strategy could be determined in accordance with the serum concentration of those drugs." @default.
• W2080462862 created "2016-06-24" @default.
• W2080462862 creator A5015822575 @default.
• W2080462862 creator A5035434845 @default.
• W2080462862 creator A5042422024 @default.
• W2080462862 creator A5057213239 @default.
• W2080462862 creator A5050120968 @default.
• W2080462862 date "2006-01-01" @default.
• W2080462862 modified "2023-09-30" @default.
• W2080462862 title "Method for Screening and Quantitative Determination of Serum Levels of Salicylic Acid, Acetaminophen, Theophylline, Phenobarbital, Bromvalerylurea, Pentobarbital, and Amobarbital Using Liquid Chromatography/Electrospray Mass Spectrometry" @default.
• W2080462862 cites W1543411693 @default.
• W2080462862 cites W1974997880 @default.
• W2080462862 cites W1985347343 @default.
• W2080462862 cites W1992338591 @default.
• W2080462862 cites W2024801049 @default.
• W2080462862 cites W2089571375 @default.
• W2080462862 cites W2096983604 @default.
• W2080462862 cites W2104645149 @default.
• W2080462862 cites W2105232006 @default.
• W2080462862 cites W2107055334 @default.
• W2080462862 cites W2109773089 @default.
• W2080462862 cites W2163679123 @default.
• W2080462862 cites W2167352214 @default.
• W2080462862 cites W2315615380 @default.
• W2080462862 doi "https://doi.org/10.1248/bpb.29.7" @default.
• W2080462862 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16394500" @default.
• W2080462862 hasPublicationYear "2006" @default.
• W2080462862 type Work @default.
• W2080462862 sameAs 2080462862 @default.
• W2080462862 citedByCount "46" @default.
• W2080462862 countsByYear W20804628622012 @default.
• W2080462862 countsByYear W20804628622014 @default.
• W2080462862 countsByYear W20804628622015 @default.
• W2080462862 countsByYear W20804628622016 @default.
• W2080462862 countsByYear W20804628622017 @default.
• W2080462862 countsByYear W20804628622018 @default.
• W2080462862 countsByYear W20804628622019 @default.
• W2080462862 countsByYear W20804628622020 @default.
• W2080462862 countsByYear W20804628622021 @default.
• W2080462862 countsByYear W20804628622022 @default.
• W2080462862 countsByYear W20804628622023 @default.
• W2080462862 crossrefType "journal-article" @default.
• W2080462862 hasAuthorship W2080462862A5015822575 @default.
• W2080462862 hasAuthorship W2080462862A5035434845 @default.
• W2080462862 hasAuthorship W2080462862A5042422024 @default.
• W2080462862 hasAuthorship W2080462862A5050120968 @default.
• W2080462862 hasAuthorship W2080462862A5057213239 @default.
• W2080462862 hasBestOaLocation W20804628621 @default.
• W2080462862 hasConcept C118552586 @default.
• W2080462862 hasConcept C162356407 @default.
• W2080462862 hasConcept C179302884 @default.
• W2080462862 hasConcept C185592680 @default.
• W2080462862 hasConcept C205345274 @default.
• W2080462862 hasConcept C2776755955 @default.
• W2080462862 hasConcept C2776918552 @default.
• W2080462862 hasConcept C2778095195 @default.
• W2080462862 hasConcept C2778186239 @default.
• W2080462862 hasConcept C2778221352 @default.
• W2080462862 hasConcept C2778722691 @default.
• W2080462862 hasConcept C40684141 @default.
• W2080462862 hasConcept C43617362 @default.
• W2080462862 hasConcept C55493867 @default.
• W2080462862 hasConcept C71924100 @default.
• W2080462862 hasConcept C95986675 @default.
• W2080462862 hasConcept C98274493 @default.
• W2080462862 hasConceptScore W2080462862C118552586 @default.
• W2080462862 hasConceptScore W2080462862C162356407 @default.
• W2080462862 hasConceptScore W2080462862C179302884 @default.
• W2080462862 hasConceptScore W2080462862C185592680 @default.
• W2080462862 hasConceptScore W2080462862C205345274 @default.
• W2080462862 hasConceptScore W2080462862C2776755955 @default.
• W2080462862 hasConceptScore W2080462862C2776918552 @default.
• W2080462862 hasConceptScore W2080462862C2778095195 @default.
• W2080462862 hasConceptScore W2080462862C2778186239 @default.
• W2080462862 hasConceptScore W2080462862C2778221352 @default.
• W2080462862 hasConceptScore W2080462862C2778722691 @default.
• W2080462862 hasConceptScore W2080462862C40684141 @default.
• W2080462862 hasConceptScore W2080462862C43617362 @default.
• W2080462862 hasConceptScore W2080462862C55493867 @default.
• W2080462862 hasConceptScore W2080462862C71924100 @default.
• W2080462862 hasConceptScore W2080462862C95986675 @default.
• W2080462862 hasConceptScore W2080462862C98274493 @default.
• W2080462862 hasIssue "1" @default.
• W2080462862 hasLocation W20804628621 @default.
• W2080462862 hasLocation W20804628622 @default.
• W2080462862 hasOpenAccess W2080462862 @default.
• W2080462862 hasPrimaryLocation W20804628621 @default.
• W2080462862 hasRelatedWork W1965847065 @default.
• W2080462862 hasRelatedWork W1976677825 @default.
• W2080462862 hasRelatedWork W2014605936 @default.
• W2080462862 hasRelatedWork W2045625298 @default.
• W2080462862 hasRelatedWork W2054447553 @default.
• W2080462862 hasRelatedWork W2068996462 @default.
• W2080462862 hasRelatedWork W2080462862 @default.
• W2080462862 hasRelatedWork W2104363614 @default.
• W2080462862 hasRelatedWork W2149450442 @default.
• W2080462862 hasRelatedWork W2333769406 @default.
• W2080462862 hasVolume "29" @default.

• next