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- W2080463384 abstract "Abstract Three experiments tested the effects of recombinant bovine granulocyte-macrophage colony-stimulating factor (rbGM-CSF) on the preimplantation bovine and ovine conceptus. There was no effect of rbGM-CSF on the secretion of total radiolabeled protein in conditioned medium, immunoreactive interferon-τ (IFNτ), antiviral activity, or prostaglandin E 2 from Day 16–18 bovine conceptuses cultured for 24 hr with [ 3 H]leucine and ±10 ng/ml rbGM-CSF. Similarly, there was no effect of 1 ng/ml rbGM-CSF on the secretion of total radiolabeled protein, IFNτ, or antiviral activity from Day 17 ovine conceptuses. There was also no beneficial effect of 1 or 10 ng/ml rbGM-CSF on the presence of immunoreactive IFNτ in conditioned medium from in vitro-produced bovine blastocysts at Day 7–8 after fertilization. Results indicate that IFNτ secretion from bovine and ovine conceptuses are unresponsive to rbGM-CSF at the concentrations tested." @default.
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- W2080463384 date "1997-05-01" @default.
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- W2080463384 title "Lack of effect of granulocyte-macrophage colony-stimulating factor on secretion of interferon-τ, other proteins, and prostaglandin E2 by the bovine and ovine conceptus" @default.
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- W2080463384 doi "https://doi.org/10.1016/s0739-7240(97)00002-7" @default.
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