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- W2080472247 abstract "The enantiomorphs of norketamine, 2-(o-chlorophenyl)- 2-aminocyclohexanone, were synthesized and screened for biological activity. Resolution was achieved by fractional crystallization of the tartrate salts. Stereochemical purity was determined using standard GC or GC-MS analysis. Preliminary pharmacological evaluations revealed that intraperitoneally injected dextrorotatory norketamine caused a greater duration of loss of righting reflex in mice than the levorotatory isomer." @default.
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- W2080472247 date "1982-08-01" @default.
- W2080472247 modified "2023-09-25" @default.
- W2080472247 title "Stereochemical Studies of Demethylated Ketamine Enantiomers" @default.
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- W2080472247 doi "https://doi.org/10.1002/jps.2600710818" @default.
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