Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080472997> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2080472997 abstract "In the past decade Raman spectroscopy (Raman) has moved out of the shadow of infrared spectroscopy (IR) and has become a routine analytical tool and is finding value in pharmaceutical process applications. Raman offers several advantages over IR vibrational information in identifying and quantifying chemicals, such as linear response to concentration independent of path length, ability to measure aqueous solutions without interference from water bands, and ease of sampling provided by fiber optic probes. However, process measurements, such as continuous monitoring or raw materials identification have been slow to develop due to instability of the wavenumber axis. Commercial suppliers of dispersive based Raman systems employ calibration references and software approaches to solve this difficult problem. To overcome this difficulty, just as dispersive IRs have been replaced by FT-IRs, we have developed an industrial hardened FT-Raman system. Furthermore, we have increased sensitivity by 25 times by employing an Si detector instead of an InGaAs detector. Here we present the abilities of this Raman system to address a number of pharmaceutical applications, including identifying raw materials in less than one minute using spectral library matching, process monitoring during early stage optimization, analyzing blended materials, and determining polymorphism." @default.
- W2080472997 created "2016-06-24" @default.
- W2080472997 creator A5015852401 @default.
- W2080472997 creator A5053128844 @default.
- W2080472997 creator A5075585031 @default.
- W2080472997 date "2004-03-08" @default.
- W2080472997 modified "2023-09-23" @default.
- W2080472997 title "Pharmaceutical process applications of Raman spectroscopy" @default.
- W2080472997 doi "https://doi.org/10.1117/12.512217" @default.
- W2080472997 hasPublicationYear "2004" @default.
- W2080472997 type Work @default.
- W2080472997 sameAs 2080472997 @default.
- W2080472997 citedByCount "1" @default.
- W2080472997 crossrefType "proceedings-article" @default.
- W2080472997 hasAuthorship W2080472997A5015852401 @default.
- W2080472997 hasAuthorship W2080472997A5053128844 @default.
- W2080472997 hasAuthorship W2080472997A5075585031 @default.
- W2080472997 hasConcept C111919701 @default.
- W2080472997 hasConcept C113196181 @default.
- W2080472997 hasConcept C120665830 @default.
- W2080472997 hasConcept C121332964 @default.
- W2080472997 hasConcept C127413603 @default.
- W2080472997 hasConcept C155386361 @default.
- W2080472997 hasConcept C165838908 @default.
- W2080472997 hasConcept C174998907 @default.
- W2080472997 hasConcept C178144697 @default.
- W2080472997 hasConcept C185592680 @default.
- W2080472997 hasConcept C192562407 @default.
- W2080472997 hasConcept C21547014 @default.
- W2080472997 hasConcept C40003534 @default.
- W2080472997 hasConcept C41008148 @default.
- W2080472997 hasConcept C43571822 @default.
- W2080472997 hasConcept C43617362 @default.
- W2080472997 hasConcept C62520636 @default.
- W2080472997 hasConcept C76155785 @default.
- W2080472997 hasConcept C94915269 @default.
- W2080472997 hasConcept C98045186 @default.
- W2080472997 hasConceptScore W2080472997C111919701 @default.
- W2080472997 hasConceptScore W2080472997C113196181 @default.
- W2080472997 hasConceptScore W2080472997C120665830 @default.
- W2080472997 hasConceptScore W2080472997C121332964 @default.
- W2080472997 hasConceptScore W2080472997C127413603 @default.
- W2080472997 hasConceptScore W2080472997C155386361 @default.
- W2080472997 hasConceptScore W2080472997C165838908 @default.
- W2080472997 hasConceptScore W2080472997C174998907 @default.
- W2080472997 hasConceptScore W2080472997C178144697 @default.
- W2080472997 hasConceptScore W2080472997C185592680 @default.
- W2080472997 hasConceptScore W2080472997C192562407 @default.
- W2080472997 hasConceptScore W2080472997C21547014 @default.
- W2080472997 hasConceptScore W2080472997C40003534 @default.
- W2080472997 hasConceptScore W2080472997C41008148 @default.
- W2080472997 hasConceptScore W2080472997C43571822 @default.
- W2080472997 hasConceptScore W2080472997C43617362 @default.
- W2080472997 hasConceptScore W2080472997C62520636 @default.
- W2080472997 hasConceptScore W2080472997C76155785 @default.
- W2080472997 hasConceptScore W2080472997C94915269 @default.
- W2080472997 hasConceptScore W2080472997C98045186 @default.
- W2080472997 hasLocation W20804729971 @default.
- W2080472997 hasOpenAccess W2080472997 @default.
- W2080472997 hasPrimaryLocation W20804729971 @default.
- W2080472997 hasRelatedWork W1831874616 @default.
- W2080472997 hasRelatedWork W2009835601 @default.
- W2080472997 hasRelatedWork W2013347690 @default.
- W2080472997 hasRelatedWork W2016974760 @default.
- W2080472997 hasRelatedWork W2083259132 @default.
- W2080472997 hasRelatedWork W2367796455 @default.
- W2080472997 hasRelatedWork W2370413442 @default.
- W2080472997 hasRelatedWork W2409850153 @default.
- W2080472997 hasRelatedWork W2947861490 @default.
- W2080472997 hasRelatedWork W4200036745 @default.
- W2080472997 isParatext "false" @default.
- W2080472997 isRetracted "false" @default.
- W2080472997 magId "2080472997" @default.
- W2080472997 workType "article" @default.