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• W2080475045 abstract "Background: Painful neuropathy is a very common complication in diabetic patients. Varioustreatment strategies like manual therapies, conservative management, drug therapy and exercise havebeen opted for this problem. Studies have shown clinical effectiveness of laser acupuncture as well.On the other hand, Amitryptaline is also a commonly used treatment for this disease. We aim tocompare the efficacy of both treatments.Objective: To assess the effect of laser acupuncture in patients suffering from painful diabeticneuropathy and its comparison with standard of care.Patients and Method: This study was conducted in Diabetic and Endocrine Management Center(DEMC) Lahore General Hospital, Lahore, Pakistan. A randomized control trial (RCT) was optedand a total of 164 patients were chosen using Non-probability purposive sampling technique. Painwas graded by using a patient friendly Visual Analogue Score (VAS), scoring from 0 to 10.Treatment was done involving organized fortnightly follow ups. Data of all patients was recorded onPerforma and was entered and analyzed for descriptive statistics in PASW 18 (IBM®. SPSS).Results: A total of 164 subjects were included in the study who were subdivided into three groupslabeled as A, B and C for laser therapy treatment, amitryptaline treatment and controls respectively.The mean age of subjects was 51.54±10.46 in Group A, 49.38±10.56 in Group B and 51.70±11.43 inGroup C. The difference of mean ages in all study groups was statistically insignificant (p-value=0.469). The average pain score in patients who received laser therapy was 5.95±0.91 beforetreatment, whereas after treatment it was 4.31±0.98. The mean pain score in subjects havingAmitryptaline before starting the treatment was 6.87±0.71 and after treatment, it was 6.23±0.98. Themean score for daily life activities in subjects who received laser therapy was 9.562.37 beforetreatment, while after treatment it was 7.56±1.54. The average score for daily life activities inpatients having Amitryptaline before starting the treatment was 9.05±1.93 and after treatment, it was8.11±1.71. Average depression and anxiety score in patients receiving laser therapy was 9.29±2.28before treatment, whereas after treatment it was found to be 7.42±1.91. Similarly, the meandepression and anxiety score in patients of Amitryptaline group before starting the treatment was9.38±2.21 and after treatment, it was 8.38±2.14. Conclusion: The mean score in our study revealsthat laser therapy shows better outcomes in improvement of pain relief, depression, anxiety and dailylife activities compared to amitryptaline in patients of diabetic neuropathy." @default.
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• W2080475045 date "2014-02-18" @default.
• W2080475045 modified "2023-09-23" @default.
• W2080475045 title "Comparison of clinical effectiveness of laser acupuncture and amitriptyline in diabetic peripheral neuropathy (DPN): a sham controlled randomized clinical trial" @default.
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• W2080475045 doi "https://doi.org/10.1117/12.2036376" @default.
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