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- W2080476729 abstract "A simple and sensitive spectrophotometric method has been developed and validated for the estimation of metformin hydrochloride in bulk and in tablet formulation. The primary amino group of metformin hydrochloride reacts with ninhydrin in alkaline medium to form a violet colour chromogen, which is determined spectrophotometrically at 570 nm. It obeyed Beer's law in the range of 8-18 mug/ml. Percentage recovery of the drug for the proposed method ranged from 97-100% indicating no interference of the tablet excipients. The proposed method was found to be accurate and precise for routine estimation of metformin hydrochloride in bulk and from tablet dosage forms." @default.
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- W2080476729 date "2009-01-01" @default.
- W2080476729 modified "2023-09-27" @default.
- W2080476729 title "Spectrophotometric method for analysis of metformin hydrochloride" @default.
- W2080476729 doi "https://doi.org/10.4103/0250-474x.51947" @default.
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