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- W2080476922 abstract "Deep brain stimulation (DBS) is a standard treatment for patients with disabling essential tremor. The short-term efficacy rate is well established.To assess the long-term effects of DBS in our series and evaluate the durability of the effects over time.Eighty-four patients implanted with unilateral or bilateral DBS for essential tremor were asked to complete three mailed-in questionnaires to assess DBS efficacy objectively and subjectively.Twenty-six patients responded, with a median follow-up of 41 months. Approximately half of the patients had more than 48 months of follow-up. At the time of follow-up, the Tremor Rating Scale was reduced from a mean score of 7 (5-8) to 3 (2-3) with DBS OFF and ON, respectively. Quality of life, measured with a subset of items of the ADL Taxonomy, improved from a mean of 26 (23-33) to 12 (12-14), comparing DBS OFF and ON. No significant differences were seen when comparing efficacy at short- (<12 months), middle- (12-48 months) or long-term (>48 months) follow-ups.DBS has long-term efficacy for tremor control. This is associated with sustained benefits in quality of life. The duration of the follow-up was not associated with any significant difference in efficacy." @default.
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- W2080476922 date "2012-01-01" @default.
- W2080476922 modified "2023-09-27" @default.
- W2080476922 title "Long-Term Effects of Deep Brain Stimulation for Essential Tremor with Subjective and Objective Quantification via Mailed-In Questionnaires" @default.
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- W2080476922 doi "https://doi.org/10.1159/000338683" @default.
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