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- W2080477805 abstract "A model for risk assessment was built for simultaneous, congener-specific PCB bioaccumulation from sediment to fish to otters (Lutra lutra). Toxic equivalence factors (TEFs) were used to sum individual congeners in otters to a toxic equivalent concentration (TEQ) relative to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Microbial dechlorination and burial in sediments and bioaccumulation are modeled to predict time trends of PCB concentrations in otters. Effects of accumulated PCBs on otters were assessed for vitamin A metabolism and reproduction, taking model uncertainty into account. Three locations in The Netherlands were modeled with PCB levels in sediment of 1 to 171 pg TEQ/g organic carbon (OC). Almost 100% reduction in litter size was predicted for the most polluted area in 1996. Due to large associated uncertainty, a period of 25 to 80 years may be needed for recovery of otter vitamin A levels and litter size at this site. Calculated median sediment quality criteria (SQC) range between 1 and 12 pg TEQ/g OC, depending on the chosen effect criterion. Uncertainty in calculated effects and SQCs is substantial and is mainly caused by uncertainty in PCB congener 126 accumulation." @default.
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- W2080477805 date "2001-01-01" @default.
- W2080477805 modified "2023-10-09" @default.
- W2080477805 title "Congener-specific model for polychlorinated biphenyl effects on otter (Lutra lutra) and associated sediment quality criteria" @default.
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- W2080477805 doi "https://doi.org/10.1002/etc.5620200124" @default.
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