FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080479955> ?p ?o ?g. }

• W2080479955 endingPage "101" @default.
• W2080479955 startingPage "100" @default.
• W2080479955 abstract "Cochrane Oral Health Group's Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, the Web of Science, OpenGrey, the US National Institutes of Health Trials Register and the World Health Organization (WHO) Clinical Trials Registry Platform. Two reviewers independently selected studies. Randomised controlled trials comparing different pulp interventions combining a pulp treatment technique and a medicament in primary teeth were considered. Data abstraction and risk of bias assessment were carried out independently by two reviewers. The primary outcomes were clinical failure and radiological failure, as defined in trials, at six, 12 and 24 months. Pairwise meta-analysis using fixed-effect models was conducted with statistical heterogeneity being assessed using I2 coefficients. Forty-seven trials involving 3910 teeth were included. All were small single centre studies. The overall level of evidence was low with only one trial having a low risk of bias, 20 a high risk and 26 unclear risk of bias. The 47 trials examined 53 different comparisons: 25 for pulpotomy, 13 for pulpectomy, 13 for direct pulp capping and two comparisons between pulpotomy and pulpectomy. Regarding pulpotomy, 14 trials compared mineral trioxide aggregate (MTA) with formocresol (FC). MTA reduced both clinical and radiological failures at six, 12 and 24 months, although the difference was not statistically significant. MTA also showed favourable results for all secondary outcomes measured, although again, differences between MTA and FC were not statistically significant (with the exception of pathological root resorption at 24 months and dentine bridge formation at six months). MTA showed favourable results compared with calcium hydroxide (CH) (two trials) for all outcomes measured, but the differences were not statistically significant (with the exception of radiological failure at 12 months). When comparing MTA with ferric sulphate (FS) (three trials), MTA had statistically significantly fewer clinical, radiological and overall failures at 24 months. This difference was not shown at six or 12 months. FC was compared with CH in seven trials and with FS in seven trials. There was a statistically significant difference in favour of FC for clinical failure at six and 12 months, and radiological failure at six, 12 and 24 months. FC also showed favourable results for all secondary outcomes measured, although differences between FC and CH were not consistently statistically significant across time points. The comparisons between FC and FS showed no statistically significantly difference between the two medicaments for any outcome at any time point. For all other comparisons of medicaments used during pulpotomies, pulpectomies or direct pulp capping, the small numbers of studies and the inconsistency in results limits any interpretation. We found no evidence to identify one superior pulpotomy medicament and technique clearly. Two medicaments may be preferable: MTA or FS. The cost of MTA may preclude its clinical use and therefore FS could be used in such situations. Regarding other comparisons for pulpectomies or direct pulp capping, the small numbers of studies undertaking the same comparison limits any interpretation." @default.
• W2080479955 created "2016-06-24" @default.
• W2080479955 creator A5009374341 @default.
• W2080479955 creator A5090881783 @default.
• W2080479955 date "2014-12-01" @default.
• W2080479955 modified "2023-10-12" @default.
• W2080479955 title "No clear evidence of superiority regarding pulp medicaments in primary molars" @default.
• W2080479955 cites W2019370274 @default.
• W2080479955 cites W2069687651 @default.
• W2080479955 cites W2096685405 @default.
• W2080479955 cites W4256214799 @default.
• W2080479955 doi "https://doi.org/10.1038/sj.ebd.6401056" @default.
• W2080479955 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25522937" @default.
• W2080479955 hasPublicationYear "2014" @default.
• W2080479955 type Work @default.
• W2080479955 sameAs 2080479955 @default.
• W2080479955 citedByCount "3" @default.
• W2080479955 countsByYear W20804799552016 @default.
• W2080479955 countsByYear W20804799552017 @default.
• W2080479955 countsByYear W20804799552023 @default.
• W2080479955 crossrefType "journal-article" @default.
• W2080479955 hasAuthorship W2080479955A5009374341 @default.
• W2080479955 hasAuthorship W2080479955A5090881783 @default.
• W2080479955 hasBestOaLocation W20804799551 @default.
• W2080479955 hasConcept C126322002 @default.
• W2080479955 hasConcept C141071460 @default.
• W2080479955 hasConcept C168563851 @default.
• W2080479955 hasConcept C18468158 @default.
• W2080479955 hasConcept C188442228 @default.
• W2080479955 hasConcept C199343813 @default.
• W2080479955 hasConcept C202271784 @default.
• W2080479955 hasConcept C2777090975 @default.
• W2080479955 hasConcept C2910719800 @default.
• W2080479955 hasConcept C44249647 @default.
• W2080479955 hasConcept C535046627 @default.
• W2080479955 hasConcept C71924100 @default.
• W2080479955 hasConcept C82789193 @default.
• W2080479955 hasConcept C95190672 @default.
• W2080479955 hasConceptScore W2080479955C126322002 @default.
• W2080479955 hasConceptScore W2080479955C141071460 @default.
• W2080479955 hasConceptScore W2080479955C168563851 @default.
• W2080479955 hasConceptScore W2080479955C18468158 @default.
• W2080479955 hasConceptScore W2080479955C188442228 @default.
• W2080479955 hasConceptScore W2080479955C199343813 @default.
• W2080479955 hasConceptScore W2080479955C202271784 @default.
• W2080479955 hasConceptScore W2080479955C2777090975 @default.
• W2080479955 hasConceptScore W2080479955C2910719800 @default.
• W2080479955 hasConceptScore W2080479955C44249647 @default.
• W2080479955 hasConceptScore W2080479955C535046627 @default.
• W2080479955 hasConceptScore W2080479955C71924100 @default.
• W2080479955 hasConceptScore W2080479955C82789193 @default.
• W2080479955 hasConceptScore W2080479955C95190672 @default.
• W2080479955 hasIssue "4" @default.
• W2080479955 hasLocation W20804799551 @default.
• W2080479955 hasLocation W20804799552 @default.
• W2080479955 hasOpenAccess W2080479955 @default.
• W2080479955 hasPrimaryLocation W20804799551 @default.
• W2080479955 hasRelatedWork W1533203939 @default.
• W2080479955 hasRelatedWork W1991636319 @default.
• W2080479955 hasRelatedWork W2011089475 @default.
• W2080479955 hasRelatedWork W2061150476 @default.
• W2080479955 hasRelatedWork W2440228370 @default.
• W2080479955 hasRelatedWork W2609078301 @default.
• W2080479955 hasRelatedWork W2789657438 @default.
• W2080479955 hasRelatedWork W3082018743 @default.
• W2080479955 hasRelatedWork W4231096291 @default.
• W2080479955 hasRelatedWork W4312668503 @default.
• W2080479955 hasVolume "15" @default.
• W2080479955 isParatext "false" @default.
• W2080479955 isRetracted "false" @default.
• W2080479955 magId "2080479955" @default.
• W2080479955 workType "article" @default.