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- W2080485540 endingPage "118" @default.
- W2080485540 startingPage "104" @default.
- W2080485540 abstract "Atypical antipsychotics offer broader efficacy and improved tolerability compared with conventional agents. Many patients currently treated with conventional antipsychotics continue to experience persistent symptoms or troublesome side effects and may benefit from a change to one of the newer atypical agents. There are also significant differences in the side-effect profiles of the atypicals, such that a switch from one atypical agent to another could offer advantages to many patients. Unfortunately, many clinicians remain uncertain about the switching process and are reluctant to initiate change. The aim of this review is to identify the indications for a switch in antipsychotic therapy with a focus on recent switching data for the atypical antipsychotic, quetiapine. The clinical aspects of quetiapine’s receptor binding characteristics are reviewed including the implications of the low D 2 antagonist properties that make quetiapine the treatment of choice when EPS persists with other atypical antipsychotics. Practical guidelines are given for managing the process of changeover, for avoiding pitfalls and for maximizing the chances of a successful switch. For example, when managing the antipsychotic crossover, it is important to consider the psychological effects of switching arising from symptom and side-effect changes. Finally, advice is provided on the assessments necessary when evaluating the success of a change in therapy, together with guidance on the optimal duration of treatment trials." @default.
- W2080485540 created "2016-06-24" @default.
- W2080485540 creator A5072573097 @default.
- W2080485540 date "2005-10-04" @default.
- W2080485540 modified "2023-09-27" @default.
- W2080485540 title "Switching antipsychotics: an updated review with a focus on quetiapine" @default.
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- W2080485540 cites W1564215811 @default.
- W2080485540 cites W1638784138 @default.
- W2080485540 cites W1787454655 @default.
- W2080485540 cites W1968998559 @default.
- W2080485540 cites W1969306344 @default.
- W2080485540 cites W1975232812 @default.
- W2080485540 cites W1981406078 @default.
- W2080485540 cites W1983341781 @default.
- W2080485540 cites W1985767662 @default.
- W2080485540 cites W1986489718 @default.
- W2080485540 cites W1986991077 @default.
- W2080485540 cites W1989545032 @default.
- W2080485540 cites W2002701207 @default.
- W2080485540 cites W2004166350 @default.
- W2080485540 cites W2008314768 @default.
- W2080485540 cites W2011554834 @default.
- W2080485540 cites W2011905864 @default.
- W2080485540 cites W2012280140 @default.
- W2080485540 cites W2013729634 @default.
- W2080485540 cites W2013918769 @default.
- W2080485540 cites W2015837785 @default.
- W2080485540 cites W2024129324 @default.
- W2080485540 cites W2025243014 @default.
- W2080485540 cites W2031575387 @default.
- W2080485540 cites W2031952693 @default.
- W2080485540 cites W2033090708 @default.
- W2080485540 cites W2037430737 @default.
- W2080485540 cites W2038135029 @default.
- W2080485540 cites W2040008186 @default.
- W2080485540 cites W2046595406 @default.
- W2080485540 cites W2049164408 @default.
- W2080485540 cites W2056486505 @default.
- W2080485540 cites W2058535391 @default.
- W2080485540 cites W2060802427 @default.
- W2080485540 cites W2061025620 @default.
- W2080485540 cites W2067217122 @default.
- W2080485540 cites W2067763161 @default.
- W2080485540 cites W2069522424 @default.
- W2080485540 cites W2070735132 @default.
- W2080485540 cites W2076845616 @default.
- W2080485540 cites W2083143542 @default.
- W2080485540 cites W2086479492 @default.
- W2080485540 cites W2091338911 @default.
- W2080485540 cites W2091790473 @default.
- W2080485540 cites W2093612777 @default.
- W2080485540 cites W2093692222 @default.
- W2080485540 cites W2095586820 @default.
- W2080485540 cites W2099466956 @default.
- W2080485540 cites W2101762862 @default.
- W2080485540 cites W2105453292 @default.
- W2080485540 cites W2108968692 @default.
- W2080485540 cites W2110569861 @default.
- W2080485540 cites W2114915862 @default.
- W2080485540 cites W2124201150 @default.
- W2080485540 cites W2127126926 @default.
- W2080485540 cites W2127381871 @default.
- W2080485540 cites W2127549664 @default.
- W2080485540 cites W2141788833 @default.
- W2080485540 cites W2146438680 @default.
- W2080485540 cites W2147934698 @default.
- W2080485540 cites W2149805979 @default.
- W2080485540 cites W2156649707 @default.
- W2080485540 cites W2162089381 @default.
- W2080485540 cites W2163445625 @default.
- W2080485540 cites W2166945572 @default.
- W2080485540 cites W2185975608 @default.
- W2080485540 cites W2196894042 @default.
- W2080485540 cites W2310905616 @default.
- W2080485540 cites W2324934416 @default.
- W2080485540 cites W2327593126 @default.
- W2080485540 cites W2409953473 @default.
- W2080485540 cites W2412342173 @default.
- W2080485540 cites W2419116898 @default.
- W2080485540 cites W2916678927 @default.
- W2080485540 cites W4232541108 @default.
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- W2080485540 doi "https://doi.org/10.1177/0269881105056668" @default.
- W2080485540 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16204323" @default.
- W2080485540 hasPublicationYear "2005" @default.
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