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- W2080485724 abstract "You have accessJournal of UrologyStone Disease: New Technology/SWL, Ureteroscopic or Percutaneous Stone Removal III1 Apr 20121829 STAGED RETROGRADE ENDOSCOPIC LITHOTRIPSY AS AN ALTERNATIVE TO PCNL: AN UPDATE Joel Bigley, Stephen Jackman, and Timothy Averch Joel BigleyJoel Bigley Pittsburgh, PA More articles by this author , Stephen JackmanStephen Jackman Pittsburgh, PA More articles by this author , and Timothy AverchTimothy Averch Pittsburgh, PA More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.1917AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Although percutaneous nephrolithotomy (PCNL) remains the gold standard for clearance of large (>2 cm) renal calculi, staged ureteroscopy has gained acceptance as an appropriate alternative in patients who are less than ideal candidates for PCNL. We previously reported our series of 23 patients who had undergone staged procedures between 2003 and 2006. We now present our updated experience. METHODS Following IRB approval, medical records were retrospectively reviewed to identify patients who had undergone staged ureteroscopy by one of two fellowship-trained endourologists between 2006 and 2010. Successful therapy was defined as fragmentation of total stone burden with no residual fragments larger than 2 mm. Data were analyzed using SPSS. RESULTS Forty-eight additional patients underwent staged ureteroscopy for upper urinary tract calculi, and six had bilateral stone disease. Age, sex, and comorbidities were similar between cohorts. Patients in the updated cohort were more likely to be obese (BMI>30, 63% vs. 30%, p=0.01) with 31% classified as morbidly obese (BMI>40) and were less likely to have a previous failed procedure (21% vs. 61%, p<0.05). Only two patients underwent staged ureteroscopy for an inability to establish percutaneous access (4%). Linear stone burden was 29.53 13.39 mm, and mean calculated stone volume was 7416 mm3 in the updated cohort. Significantly more patients progressed to second-stage operations (90.7% vs. 47.8%, p<0.001), and nine (19%) required three or more stages. Stone-free rates remained similar between groups (74.1% vs. 73.9%, p=1.0). In the 14 stone burdens of the updated cohort that were not completely cleared, five (36%) were the result of an inability to adequately deflect the ureteroscope to the lower pole. In the combined cohort, linear stone burden >40 mm and calculated stone volume >15,000 mm3 were once again associated with treatment failure (23%, 33%). CONCLUSIONS Our combined series, consisting of 71 patients, represents the largest single-institution experience of staged REL as an alternative to PCNL. Our practice has evolved to use staged REL as a primary treatment in patients with medical cormorbidities regardless of previous treatment failure. Patients with unilateral stone burden <4 cm and significant comorbidities should be counseled that staged REL provides stone-free rates greater than 70% but may require two or more operative sessions. © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e739-e740 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.MetricsAuthor Information Joel Bigley Pittsburgh, PA More articles by this author Stephen Jackman Pittsburgh, PA More articles by this author Timothy Averch Pittsburgh, PA More articles by this author Expand All Advertisement Advertisement PDF DownloadLoading ..." @default.
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- W2080485724 title "1829 STAGED RETROGRADE ENDOSCOPIC LITHOTRIPSY AS AN ALTERNATIVE TO PCNL: AN UPDATE" @default.
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