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• W2080493098 abstract "1. Prenatal stress in rats has been shown to produce long-term behavioral, neuroendocrine and neurochemical changes. These changes may model aspects of human depressive illness. 2. In this pilot investigation, adult male offspring exposed to stress in utero and nonstressed controls were studied using 24-hour electroencephalographic sleep recordings. 3. Prenatally stressed animals demonstrated reduced latency to the onset of rapid eye movement (REM) sleep, prolongation of the first REM episode, and diminished slowwave sleep. 4. Although preliminary, the observed changes parallel those seen in studies of human depression. These data further support the face validity of the prenatal stress model as a potential tool for future studies on the pathophysiology of depressive disorder." @default.
• W2080493098 created "2016-06-24" @default.
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• W2080493098 date "1999-07-01" @default.
• W2080493098 modified "2023-09-30" @default.
• W2080493098 title "Prenatal stress is associated with depression-related electroencephalographic sleep changes in adult male rats: A preliminary report" @default.
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• W2080493098 doi "https://doi.org/10.1016/s0278-5846(99)00036-6" @default.
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