FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080493571> ?p ?o ?g. }

• W2080493571 endingPage "2403" @default.
• W2080493571 startingPage "2399" @default.
• W2080493571 abstract "Icariin is one of the major active flavonoids constituents of Epimedium brevicornum MAXIM (Berberidaceae). Icariin and E. brevicornum have a wide range of pharmacological activities. Abnormality in the hypothalamic-pituitary-adrenal (HPA) axis is considered to be a key neurobilogical factor in major depression, and cytokines have a close relationship with the activation of the HPA axis. In the present study, the aim was to determine whether icariin possesses an antidepressant-like activity, and to explore the effects of icariin on the HPA axis and cytokine levels in chronic mild stress (CMS) model of depression in Sprague-Dawley rats. Icariin significantly increased the sucrose intake of CMS-treated rats from week 3. It not only attenuated the CMS-induced increases in serum corticotropin-releasing factor (CRF) and cortisol levels, but also reversed the abnormal levels of serum interleukin-6 (IL-6) and tumor-necrosis-factor alpha (TNF-α) to the normal in the stressed rats. These results suggested that icariin possessed an antidepressant-like property that was at least in part mediated by neuroendocrine and immune systems." @default.
• W2080493571 created "2016-06-24" @default.
• W2080493571 creator A5012782075 @default.
• W2080493571 creator A5060424374 @default.
• W2080493571 creator A5080423822 @default.
• W2080493571 creator A5082839498 @default.
• W2080493571 date "2006-01-01" @default.
• W2080493571 modified "2023-10-11" @default.
• W2080493571 title "Effects of Icariin on Hypothalamic-Pituitary-Adrenal Axis Action and Cytokine Levels in Stressed Sprague-Dawley Rats" @default.
• W2080493571 cites W102195264 @default.
• W2080493571 cites W114026363 @default.
• W2080493571 cites W144535883 @default.
• W2080493571 cites W1984760175 @default.
• W2080493571 cites W1993513360 @default.
• W2080493571 cites W1994284751 @default.
• W2080493571 cites W1996157110 @default.
• W2080493571 cites W2014593621 @default.
• W2080493571 cites W2020659371 @default.
• W2080493571 cites W2022979746 @default.
• W2080493571 cites W2023754337 @default.
• W2080493571 cites W2024951540 @default.
• W2080493571 cites W2026592886 @default.
• W2080493571 cites W2032910321 @default.
• W2080493571 cites W2036405052 @default.
• W2080493571 cites W2038679778 @default.
• W2080493571 cites W2049113427 @default.
• W2080493571 cites W2066457796 @default.
• W2080493571 cites W2088751222 @default.
• W2080493571 cites W2092009769 @default.
• W2080493571 cites W2093081301 @default.
• W2080493571 cites W2108126412 @default.
• W2080493571 cites W2143315463 @default.
• W2080493571 cites W2161548027 @default.
• W2080493571 cites W2323040745 @default.
• W2080493571 cites W4231341273 @default.
• W2080493571 cites W91245769 @default.
• W2080493571 doi "https://doi.org/10.1248/bpb.29.2399" @default.
• W2080493571 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17142971" @default.
• W2080493571 hasPublicationYear "2006" @default.
• W2080493571 type Work @default.
• W2080493571 sameAs 2080493571 @default.
• W2080493571 citedByCount "57" @default.
• W2080493571 countsByYear W20804935712012 @default.
• W2080493571 countsByYear W20804935712013 @default.
• W2080493571 countsByYear W20804935712014 @default.
• W2080493571 countsByYear W20804935712015 @default.
• W2080493571 countsByYear W20804935712016 @default.
• W2080493571 countsByYear W20804935712017 @default.
• W2080493571 countsByYear W20804935712018 @default.
• W2080493571 countsByYear W20804935712019 @default.
• W2080493571 countsByYear W20804935712020 @default.
• W2080493571 countsByYear W20804935712021 @default.
• W2080493571 countsByYear W20804935712022 @default.
• W2080493571 countsByYear W20804935712023 @default.
• W2080493571 crossrefType "journal-article" @default.
• W2080493571 hasAuthorship W2080493571A5012782075 @default.
• W2080493571 hasAuthorship W2080493571A5060424374 @default.
• W2080493571 hasAuthorship W2080493571A5080423822 @default.
• W2080493571 hasAuthorship W2080493571A5082839498 @default.
• W2080493571 hasBestOaLocation W20804935711 @default.
• W2080493571 hasConcept C126322002 @default.
• W2080493571 hasConcept C134018914 @default.
• W2080493571 hasConcept C142724271 @default.
• W2080493571 hasConcept C17991360 @default.
• W2080493571 hasConcept C188947578 @default.
• W2080493571 hasConcept C204787440 @default.
• W2080493571 hasConcept C2778690821 @default.
• W2080493571 hasConcept C2779146795 @default.
• W2080493571 hasConcept C2779177272 @default.
• W2080493571 hasConcept C2780546910 @default.
• W2080493571 hasConcept C2780685212 @default.
• W2080493571 hasConcept C2781161787 @default.
• W2080493571 hasConcept C2781393221 @default.
• W2080493571 hasConcept C71315377 @default.
• W2080493571 hasConcept C71924100 @default.
• W2080493571 hasConceptScore W2080493571C126322002 @default.
• W2080493571 hasConceptScore W2080493571C134018914 @default.
• W2080493571 hasConceptScore W2080493571C142724271 @default.
• W2080493571 hasConceptScore W2080493571C17991360 @default.
• W2080493571 hasConceptScore W2080493571C188947578 @default.
• W2080493571 hasConceptScore W2080493571C204787440 @default.
• W2080493571 hasConceptScore W2080493571C2778690821 @default.
• W2080493571 hasConceptScore W2080493571C2779146795 @default.
• W2080493571 hasConceptScore W2080493571C2779177272 @default.
• W2080493571 hasConceptScore W2080493571C2780546910 @default.
• W2080493571 hasConceptScore W2080493571C2780685212 @default.
• W2080493571 hasConceptScore W2080493571C2781161787 @default.
• W2080493571 hasConceptScore W2080493571C2781393221 @default.
• W2080493571 hasConceptScore W2080493571C71315377 @default.
• W2080493571 hasConceptScore W2080493571C71924100 @default.
• W2080493571 hasIssue "12" @default.
• W2080493571 hasLocation W20804935711 @default.
• W2080493571 hasLocation W20804935712 @default.
• W2080493571 hasOpenAccess W2080493571 @default.
• W2080493571 hasPrimaryLocation W20804935711 @default.
• W2080493571 hasRelatedWork W1485026357 @default.
• W2080493571 hasRelatedWork W1977918131 @default.
• W2080493571 hasRelatedWork W1991870710 @default.

• next