FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080497256> ?p ?o ?g. }

• W2080497256 endingPage "451" @default.
• W2080497256 startingPage "444" @default.
• W2080497256 abstract "The studies on the factors that regulate the biology of the neuroblastoma cell lines may offer important information on the development of tissues and organs that derive from the neural crest. In the present paper we study the action of epidermal growth factor (EGF) on two human neuroblastoma cell lines: SK-N-SH which is composed at least of two cellular phenotypes (neuroblastic and melanocytic/glial cells), and its pure neuroblastic subclone SH-SY5Y. The results show that EGF (10 ng/ml) significantly stimulates the incorporation of [3H]-thymidine in the SK-N-SH cells only in the presence of fetal bovine serum (FBS) (control = 58285 ± 9327 cpm; EGF =75523 ± 4457; p<0.05). Such effect is not observed in the presence of a chemical defined medium, that is, in the absence of FBS (control = 100997 ± 4375; EGF = 95268 ± 4683; NS). In the SH-SY5Y cells the EGF does not modify the incorporation of [3H]thymidine either in the presence of 10% of BFS (control = 113838 ± 6978; EGF = 119434 ± 9441; NS) or in its absence (control = 46197 ± 3335; EGF = 44472 ± 3493; NS). The results here reported suggest that: a) EGF may affect the proliferation of cells derived from a primary human neuroblastoma; b) this is evident by the EGF-induced increase of [3H]-thymidine incorporation in SK-N-SH cells; c) it is required the presence of other growth factors, present in the FBS, for the mitogenic action to be accomplished; d) since the pure neuroblastic SH-SY5Y cell line are refractory to the EGF, the effects observed in SK-N-SH cells probably occur on the melanocytic/glial cell subpopulation." @default.
• W2080497256 created "2016-06-24" @default.
• W2080497256 creator A5047994517 @default.
• W2080497256 creator A5082782463 @default.
• W2080497256 creator A5084826127 @default.
• W2080497256 creator A5088952771 @default.
• W2080497256 date "1997-09-01" @default.
• W2080497256 modified "2023-10-15" @default.
• W2080497256 title "Effects of epidermal growth factor on the [3H]-thymidine uptake in the SK-N-SH and SH-SY5Y human neuroblastoma cell lines" @default.
• W2080497256 cites W1513460865 @default.
• W2080497256 cites W1853725381 @default.
• W2080497256 cites W1972775107 @default.
• W2080497256 cites W1980008415 @default.
• W2080497256 cites W1980131968 @default.
• W2080497256 cites W1988677415 @default.
• W2080497256 cites W1994500634 @default.
• W2080497256 cites W1996315381 @default.
• W2080497256 cites W1996649012 @default.
• W2080497256 cites W2000167322 @default.
• W2080497256 cites W2001163784 @default.
• W2080497256 cites W2009981615 @default.
• W2080497256 cites W2015304387 @default.
• W2080497256 cites W2015851954 @default.
• W2080497256 cites W2015954525 @default.
• W2080497256 cites W2017619951 @default.
• W2080497256 cites W2018549162 @default.
• W2080497256 cites W2059917807 @default.
• W2080497256 cites W2066860072 @default.
• W2080497256 cites W2070379621 @default.
• W2080497256 cites W2075796579 @default.
• W2080497256 cites W2081186080 @default.
• W2080497256 cites W2093875398 @default.
• W2080497256 cites W2103416238 @default.
• W2080497256 cites W2330476624 @default.
• W2080497256 doi "https://doi.org/10.1590/s0004-282x1997000300016" @default.
• W2080497256 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9629363" @default.
• W2080497256 hasPublicationYear "1997" @default.
• W2080497256 type Work @default.
• W2080497256 sameAs 2080497256 @default.
• W2080497256 citedByCount "8" @default.
• W2080497256 countsByYear W20804972562013 @default.
• W2080497256 countsByYear W20804972562020 @default.
• W2080497256 countsByYear W20804972562021 @default.
• W2080497256 crossrefType "journal-article" @default.
• W2080497256 hasAuthorship W2080497256A5047994517 @default.
• W2080497256 hasAuthorship W2080497256A5082782463 @default.
• W2080497256 hasAuthorship W2080497256A5084826127 @default.
• W2080497256 hasAuthorship W2080497256A5088952771 @default.
• W2080497256 hasBestOaLocation W20804972561 @default.
• W2080497256 hasConcept C126322002 @default.
• W2080497256 hasConcept C134018914 @default.
• W2080497256 hasConcept C153911025 @default.
• W2080497256 hasConcept C170493617 @default.
• W2080497256 hasConcept C202751555 @default.
• W2080497256 hasConcept C2775960820 @default.
• W2080497256 hasConcept C2776362946 @default.
• W2080497256 hasConcept C2776715637 @default.
• W2080497256 hasConcept C2777108182 @default.
• W2080497256 hasConcept C2779083432 @default.
• W2080497256 hasConcept C2779404806 @default.
• W2080497256 hasConcept C54355233 @default.
• W2080497256 hasConcept C55493867 @default.
• W2080497256 hasConcept C62112901 @default.
• W2080497256 hasConcept C71924100 @default.
• W2080497256 hasConcept C81885089 @default.
• W2080497256 hasConcept C86803240 @default.
• W2080497256 hasConceptScore W2080497256C126322002 @default.
• W2080497256 hasConceptScore W2080497256C134018914 @default.
• W2080497256 hasConceptScore W2080497256C153911025 @default.
• W2080497256 hasConceptScore W2080497256C170493617 @default.
• W2080497256 hasConceptScore W2080497256C202751555 @default.
• W2080497256 hasConceptScore W2080497256C2775960820 @default.
• W2080497256 hasConceptScore W2080497256C2776362946 @default.
• W2080497256 hasConceptScore W2080497256C2776715637 @default.
• W2080497256 hasConceptScore W2080497256C2777108182 @default.
• W2080497256 hasConceptScore W2080497256C2779083432 @default.
• W2080497256 hasConceptScore W2080497256C2779404806 @default.
• W2080497256 hasConceptScore W2080497256C54355233 @default.
• W2080497256 hasConceptScore W2080497256C55493867 @default.
• W2080497256 hasConceptScore W2080497256C62112901 @default.
• W2080497256 hasConceptScore W2080497256C71924100 @default.
• W2080497256 hasConceptScore W2080497256C81885089 @default.
• W2080497256 hasConceptScore W2080497256C86803240 @default.
• W2080497256 hasIssue "3A" @default.
• W2080497256 hasLocation W20804972561 @default.
• W2080497256 hasLocation W20804972562 @default.
• W2080497256 hasOpenAccess W2080497256 @default.
• W2080497256 hasPrimaryLocation W20804972561 @default.
• W2080497256 hasRelatedWork W1999660566 @default.
• W2080497256 hasRelatedWork W2011400055 @default.
• W2080497256 hasRelatedWork W2022678399 @default.
• W2080497256 hasRelatedWork W2079251901 @default.
• W2080497256 hasRelatedWork W2080497256 @default.
• W2080497256 hasRelatedWork W2095468036 @default.
• W2080497256 hasRelatedWork W2144562624 @default.
• W2080497256 hasRelatedWork W2171223757 @default.
• W2080497256 hasRelatedWork W4236934633 @default.
• W2080497256 hasRelatedWork W1995193459 @default.

• next