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• W2080497698 abstract "ABSTRACT The pharmacokinetics of lipid-bound and liberated amphotericin B (AMB) was assessed in 11 critically ill patients with cholestatic liver disease (CSLD) and in 9 subjects with normal liver function treated with AMB colloidal dispersion (ABCD). Exposure to lipid-bound AMB was higher in patients with CSLD. Levels of liberated AMB were elevated by CSLD only after the first dose, whereas its pharmacokinetics was unaffected at steady state. The standard dosage of ABCD is probably adequate for patients with CSLD." @default.
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• W2080497698 date "2012-10-01" @default.
• W2080497698 modified "2023-10-16" @default.
• W2080497698 title "Pharmacokinetics of Amphotericin B Colloidal Dispersion in Critically Ill Patients with Cholestatic Liver Disease" @default.
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• W2080497698 doi "https://doi.org/10.1128/aac.00690-12" @default.
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