Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080498431> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2080498431 endingPage "1400" @default.
- W2080498431 startingPage "1395" @default.
- W2080498431 abstract "Human plasma low-density lipoproteins of 1.032-1.043 g/mL density were totally delipidized. The reduced and carboxymethylated apolipoprotein B was incubated with 50 mM [14C]methylamine at pH 8.5 at 30 degrees C. Covalent incorporation of [14C]methylamine was observed with concomitant generation of new sulfhydryl groups, which could be blocked with [3H]- or [14C]iodoacetic acid. One type of the [14C]methylamine-modified products was separated from the protein and was found to be lipid in nature. Its Rf on thin-layer chromatography (TLC) was similar to that of the synthetic N-methyl fatty acyl amides. After purification with TLC and transesterification in 3 N methanolic HCl, methyl esters of C16 and C18 fatty acids at 1:1 ratio were identified by gas-liquid chromatography. The transesterification method was verified with the known N-methyl fatty acyl amides. These results suggest the presence of labile thiol ester linked palmitate and stearate in apolipoprotein B. Under mild alkaline conditions, the thiol ester bonds are broken by methylamine and form N-methyl fatty acyl amides and release new-SH groups. Intramolecular thiol ester bonds linked between cysteine side chains and acidic amino acid residues were also found present, which will be reported separately." @default.
- W2080498431 created "2016-06-24" @default.
- W2080498431 creator A5011921531 @default.
- W2080498431 creator A5059833896 @default.
- W2080498431 creator A5082729074 @default.
- W2080498431 date "1988-03-08" @default.
- W2080498431 modified "2023-09-27" @default.
- W2080498431 title "Identification of the thiol ester linked lipids in apolipoprotein B" @default.
- W2080498431 cites W146404358 @default.
- W2080498431 cites W1534835840 @default.
- W2080498431 cites W1571225670 @default.
- W2080498431 cites W1571793851 @default.
- W2080498431 cites W1572595133 @default.
- W2080498431 cites W1775749144 @default.
- W2080498431 cites W1799849637 @default.
- W2080498431 cites W1985850595 @default.
- W2080498431 cites W2010002190 @default.
- W2080498431 cites W2022604481 @default.
- W2080498431 cites W2033553129 @default.
- W2080498431 cites W2039575017 @default.
- W2080498431 cites W2048934789 @default.
- W2080498431 cites W2048960863 @default.
- W2080498431 cites W2058280426 @default.
- W2080498431 cites W2064128417 @default.
- W2080498431 cites W2064958205 @default.
- W2080498431 cites W2070983507 @default.
- W2080498431 cites W2079159599 @default.
- W2080498431 cites W2079340910 @default.
- W2080498431 cites W2083744040 @default.
- W2080498431 cites W2091649029 @default.
- W2080498431 cites W2095433190 @default.
- W2080498431 cites W2138841151 @default.
- W2080498431 cites W2156799866 @default.
- W2080498431 cites W2399671735 @default.
- W2080498431 cites W75042735 @default.
- W2080498431 doi "https://doi.org/10.1021/bi00405a001" @default.
- W2080498431 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3365394" @default.
- W2080498431 hasPublicationYear "1988" @default.
- W2080498431 type Work @default.
- W2080498431 sameAs 2080498431 @default.
- W2080498431 citedByCount "46" @default.
- W2080498431 crossrefType "journal-article" @default.
- W2080498431 hasAuthorship W2080498431A5011921531 @default.
- W2080498431 hasAuthorship W2080498431A5059833896 @default.
- W2080498431 hasAuthorship W2080498431A5082729074 @default.
- W2080498431 hasConcept C178790620 @default.
- W2080498431 hasConcept C181199279 @default.
- W2080498431 hasConcept C185592680 @default.
- W2080498431 hasConcept C2777241282 @default.
- W2080498431 hasConcept C2778834346 @default.
- W2080498431 hasConcept C2778969155 @default.
- W2080498431 hasConcept C2779201268 @default.
- W2080498431 hasConcept C2779607525 @default.
- W2080498431 hasConcept C2781324293 @default.
- W2080498431 hasConcept C43617362 @default.
- W2080498431 hasConcept C543025807 @default.
- W2080498431 hasConceptScore W2080498431C178790620 @default.
- W2080498431 hasConceptScore W2080498431C181199279 @default.
- W2080498431 hasConceptScore W2080498431C185592680 @default.
- W2080498431 hasConceptScore W2080498431C2777241282 @default.
- W2080498431 hasConceptScore W2080498431C2778834346 @default.
- W2080498431 hasConceptScore W2080498431C2778969155 @default.
- W2080498431 hasConceptScore W2080498431C2779201268 @default.
- W2080498431 hasConceptScore W2080498431C2779607525 @default.
- W2080498431 hasConceptScore W2080498431C2781324293 @default.
- W2080498431 hasConceptScore W2080498431C43617362 @default.
- W2080498431 hasConceptScore W2080498431C543025807 @default.
- W2080498431 hasIssue "5" @default.
- W2080498431 hasLocation W20804984311 @default.
- W2080498431 hasLocation W20804984312 @default.
- W2080498431 hasOpenAccess W2080498431 @default.
- W2080498431 hasPrimaryLocation W20804984311 @default.
- W2080498431 hasRelatedWork W1984931789 @default.
- W2080498431 hasRelatedWork W2006847462 @default.
- W2080498431 hasRelatedWork W2037149241 @default.
- W2080498431 hasRelatedWork W2153373129 @default.
- W2080498431 hasRelatedWork W2349162028 @default.
- W2080498431 hasRelatedWork W2352337789 @default.
- W2080498431 hasRelatedWork W2520058426 @default.
- W2080498431 hasRelatedWork W2531534298 @default.
- W2080498431 hasRelatedWork W3015167546 @default.
- W2080498431 hasRelatedWork W3016830989 @default.
- W2080498431 hasVolume "27" @default.
- W2080498431 isParatext "false" @default.
- W2080498431 isRetracted "false" @default.
- W2080498431 magId "2080498431" @default.
- W2080498431 workType "article" @default.