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- W2080499334 abstract "‘Classical’ models of haematopoiesis depict a branching tree in which the first bifurcation gives rise to separate progenitors for the myeloid/erythroid and lymphoid families of cells [1]. This simple view has been challenged by the identification of haematopoietic progenitors that generate both lymphocytes and myeloid cells but not erythrocytes or megakaryocytes (reviewed in [2,3]). To progress further in our understanding of haematopoietic, two issues need to be resolved (i) to arrive at a consensus on the precise relationships between the various haematopoietic lineages, and (ii) to learn how cells gain access to their final mono-lineage fate at the expense of other options." @default.
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- W2080499334 date "2009-10-01" @default.
- W2080499334 modified "2023-09-30" @default.
- W2080499334 title "Lineage determination in haematopoiesis: Quo Vadis?" @default.
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- W2080499334 doi "https://doi.org/10.1016/j.it.2009.07.003" @default.
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