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• W2080499638 abstract "Summary The reactivities of peroxidase‐labelled concanavalin A (con A: 20 jug/ ml) with sections from various avian lymphoid organs were compared. With chicken bursae, con A binding and subsequent differential staining detected a non‐lymphoid leukocyte population distributed throughout the sections. A comparable population was not observed in sections from the gland of Harder. With free cells, con A at low concentrations was found to selectively bind to both macrophages and heterophils but not to lymphocytes. Flow cytometric analysis with fluorescein isothiocyanate‐labelled con A . also confirmed this selective binding. Peroxidase‐labelled con A was used to detect non‐lymphoid leukocytes present in areas of metastasised tumours in tissues of quail‐chicken hybrids. Such staining was not seen in comparable normal tissues. Evidence that the tumour‐localised leukocytes were macrophages was shown by the reactivity of these cells with a monoclonal anti‐chicken la antibody. It is concluded that con A binding can be used to identify tissue macrophages and may provide a useful diagnostic tool in birds." @default.
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• W2080499638 date "1988-01-01" @default.
• W2080499638 modified "2023-10-18" @default.
• W2080499638 title "Detection of avian macrophages with concanavalin a" @default.
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• W2080499638 doi "https://doi.org/10.1080/03079458808436503" @default.
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