FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080505481> ?p ?o ?g. }

• W2080505481 abstract "Plants are natural producers of chemical substances, providing potential treatment of human ailments since ancient times. Some herbal chemicals in medicinal plants of traditional and modern medicine carry the risk of herb induced liver injury (HILI) with a severe or potentially lethal clinical course, and the requirement of a liver transplant. Discontinuation of herbal use is mandatory in time when HILI is first suspected as diagnosis. Although, herbal hepatotoxicity is of utmost clinical and regulatory importance, lack of a stringent causality assessment remains a major issue for patients with suspected HILI, while this problem is best overcome by the use of the hepatotoxicity specific CIOMS (Council for International Organizations of Medical Sciences) scale and the evaluation of unintentional reexposure test results. Sixty five different commonly used herbs, herbal drugs, and herbal supplements and 111 different herbs or herbal mixtures of the traditional Chinese medicine (TCM) are reported causative for liver disease, with levels of causality proof that appear rarely conclusive. Encouraging steps in the field of herbal hepatotoxicity focus on introducing analytical methods that identify cases of intrinsic hepatotoxicity caused by pyrrolizidine alkaloids, and on omics technologies, including genomics, proteomics, metabolomics, and assessing circulating micro-RNA in the serum of some patients with intrinsic hepatotoxicity. It remains to be established whether these new technologies can identify idiosyncratic HILI cases. To enhance its globalization, herbal medicine should universally be marketed as herbal drugs under strict regulatory surveillance in analogy to regulatory approved chemical drugs, proving a positive risk/benefit profile by enforcing evidence based clinical trials and excellent herbal drug quality." @default.
• W2080505481 created "2016-06-24" @default.
• W2080505481 creator A5019675536 @default.
• W2080505481 creator A5075491786 @default.
• W2080505481 date "2015-04-23" @default.
• W2080505481 modified "2023-10-14" @default.
• W2080505481 title "Herbal hepatotoxicity in traditional and modern medicine: actual key issues and new encouraging steps" @default.
• W2080505481 cites W100877704 @default.
• W2080505481 cites W101923745 @default.
• W2080505481 cites W119198626 @default.
• W2080505481 cites W129967296 @default.
• W2080505481 cites W13831370 @default.
• W2080505481 cites W1509622618 @default.
• W2080505481 cites W1511779289 @default.
• W2080505481 cites W1514025904 @default.
• W2080505481 cites W155804842 @default.
• W2080505481 cites W1566598526 @default.
• W2080505481 cites W1571098654 @default.
• W2080505481 cites W1575688712 @default.
• W2080505481 cites W1579061409 @default.
• W2080505481 cites W1602972237 @default.
• W2080505481 cites W1635123902 @default.
• W2080505481 cites W1654432978 @default.
• W2080505481 cites W1684412556 @default.
• W2080505481 cites W1748788205 @default.
• W2080505481 cites W175295715 @default.
• W2080505481 cites W175700396 @default.
• W2080505481 cites W1763632026 @default.
• W2080505481 cites W1763860073 @default.
• W2080505481 cites W1842335150 @default.
• W2080505481 cites W185148022 @default.
• W2080505481 cites W1854694646 @default.
• W2080505481 cites W1877013367 @default.
• W2080505481 cites W1922110341 @default.
• W2080505481 cites W1932314651 @default.
• W2080505481 cites W1959664138 @default.
• W2080505481 cites W1963568502 @default.
• W2080505481 cites W1963741464 @default.
• W2080505481 cites W1964694228 @default.
• W2080505481 cites W1965677989 @default.
• W2080505481 cites W1965877841 @default.
• W2080505481 cites W1966268750 @default.
• W2080505481 cites W1966913850 @default.
• W2080505481 cites W1967734409 @default.
• W2080505481 cites W1969175618 @default.
• W2080505481 cites W1969249647 @default.
• W2080505481 cites W1970497982 @default.
• W2080505481 cites W1971646022 @default.
• W2080505481 cites W1972184463 @default.
• W2080505481 cites W1972199218 @default.
• W2080505481 cites W1973202996 @default.
• W2080505481 cites W1973742414 @default.
• W2080505481 cites W1975440270 @default.
• W2080505481 cites W1975490265 @default.
• W2080505481 cites W1975963539 @default.
• W2080505481 cites W1977380087 @default.
• W2080505481 cites W1980672038 @default.
• W2080505481 cites W1980984989 @default.
• W2080505481 cites W1981318411 @default.
• W2080505481 cites W1983671502 @default.
• W2080505481 cites W1984345292 @default.
• W2080505481 cites W1986185559 @default.
• W2080505481 cites W1986261486 @default.
• W2080505481 cites W1987290953 @default.
• W2080505481 cites W1987945561 @default.
• W2080505481 cites W1988185818 @default.
• W2080505481 cites W1989387726 @default.
• W2080505481 cites W1990708621 @default.
• W2080505481 cites W1991372434 @default.
• W2080505481 cites W1992982381 @default.
• W2080505481 cites W1994340980 @default.
• W2080505481 cites W1994487750 @default.
• W2080505481 cites W1994541453 @default.
• W2080505481 cites W1994847018 @default.
• W2080505481 cites W1994869535 @default.
• W2080505481 cites W1995080434 @default.
• W2080505481 cites W1995338601 @default.
• W2080505481 cites W1995546772 @default.
• W2080505481 cites W1997435071 @default.
• W2080505481 cites W1999655719 @default.
• W2080505481 cites W2000318092 @default.
• W2080505481 cites W2001075419 @default.
• W2080505481 cites W2002026740 @default.
• W2080505481 cites W2002292859 @default.
• W2080505481 cites W2002681936 @default.
• W2080505481 cites W2004018147 @default.
• W2080505481 cites W2006189677 @default.
• W2080505481 cites W2006535418 @default.
• W2080505481 cites W2010187863 @default.
• W2080505481 cites W2010234450 @default.
• W2080505481 cites W2011617446 @default.
• W2080505481 cites W2012054541 @default.
• W2080505481 cites W2013759157 @default.
• W2080505481 cites W2013944640 @default.
• W2080505481 cites W2014141124 @default.
• W2080505481 cites W2014526413 @default.
• W2080505481 cites W2014946835 @default.
• W2080505481 cites W2017750961 @default.
• W2080505481 cites W2018310243 @default.
• W2080505481 cites W2018604503 @default.

• next