FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080521160> ?p ?o ?g. }

• W2080521160 endingPage "1536" @default.
• W2080521160 startingPage "1525" @default.
• W2080521160 abstract "Objectives To evaluate the clinical burden of extraintestinal Clostridium difficile infection (CDI) seen at a single institution and to characterize the management and outcomes of these rare infections. Patients and Methods A retrospective medical record review was conducted to identify patients with isolation of C difficile from extraintestinal sites from January 1, 2004, through December 31, 2013. Medical records were reviewed and data, including demographic characteristics, microbiology, clinical associations, management, and infection outcomes, were abstracted. Results Overall, 40 patients with extraintestinal CDI were identified: 25 had abdominopelvic infections, 11 had bloodstream infections, 3 had wound infections, and 1 had pulmonary infection. C difficile was isolated with other organisms in 63% of cases. A total of 85% of infections were nosocomial. Factors associated with extraintestinal CDI included surgical manipulation of the gastrointestinal tract (88%), recent antibiotic exposure (88%), malignant tumors (50%), and proton pump inhibitor use (50%). Diarrhea was present in 18 patients (45%), 12 of whom had C difficile polymerase chain reaction (PCR)–positive stool samples. All isolates tested were susceptible to metronidazole and piperacillin-tazobactam. Management included both antimicrobial therapy and guided drainage or surgical intervention in all but one patient. The infection-associated mortality rate was 25%, with death a median of 16 days (range, 1-61 days) after isolation of C difficile. Conclusion Extraintestinal CDI is uncommon and often occurs in patients with surgical manipulation of the gastrointestinal tract and well-recognized risk factors for intestinal CDI. Management of extraintestinal CDI includes both antimicrobial and surgical therapies. Extraintestinal CDI is characterized by poor outcome with high mortality." @default.
• W2080521160 created "2016-06-24" @default.
• W2080521160 creator A5016245381 @default.
• W2080521160 creator A5033532763 @default.
• W2080521160 creator A5055691879 @default.
• W2080521160 creator A5067156920 @default.
• W2080521160 creator A5077792271 @default.
• W2080521160 date "2014-11-01" @default.
• W2080521160 modified "2023-09-24" @default.
• W2080521160 title "Extraintestinal Clostridium difficile Infections: A Single-Center Experience" @default.
• W2080521160 cites W1853783810 @default.
• W2080521160 cites W1966018464 @default.
• W2080521160 cites W1969804380 @default.
• W2080521160 cites W1977799841 @default.
• W2080521160 cites W2001117769 @default.
• W2080521160 cites W2006374464 @default.
• W2080521160 cites W2007196615 @default.
• W2080521160 cites W2013868973 @default.
• W2080521160 cites W2014085549 @default.
• W2080521160 cites W2017804465 @default.
• W2080521160 cites W2038146905 @default.
• W2080521160 cites W2051839115 @default.
• W2080521160 cites W2065777365 @default.
• W2080521160 cites W2074300651 @default.
• W2080521160 cites W2103736482 @default.
• W2080521160 cites W2104518766 @default.
• W2080521160 cites W2111990189 @default.
• W2080521160 cites W2120039056 @default.
• W2080521160 cites W2120123777 @default.
• W2080521160 cites W2120529286 @default.
• W2080521160 cites W2123749188 @default.
• W2080521160 cites W2132243859 @default.
• W2080521160 cites W2135302615 @default.
• W2080521160 cites W2136958722 @default.
• W2080521160 cites W2148285475 @default.
• W2080521160 cites W2155317599 @default.
• W2080521160 cites W2155800098 @default.
• W2080521160 cites W2158871837 @default.
• W2080521160 cites W2162404768 @default.
• W2080521160 cites W2164089633 @default.
• W2080521160 cites W2166660180 @default.
• W2080521160 cites W2331725203 @default.
• W2080521160 cites W2342087544 @default.
• W2080521160 doi "https://doi.org/10.1016/j.mayocp.2014.07.012" @default.
• W2080521160 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25245597" @default.
• W2080521160 hasPublicationYear "2014" @default.
• W2080521160 type Work @default.
• W2080521160 sameAs 2080521160 @default.
• W2080521160 citedByCount "32" @default.
• W2080521160 countsByYear W20805211602015 @default.
• W2080521160 countsByYear W20805211602016 @default.
• W2080521160 countsByYear W20805211602017 @default.
• W2080521160 countsByYear W20805211602018 @default.
• W2080521160 countsByYear W20805211602020 @default.
• W2080521160 countsByYear W20805211602021 @default.
• W2080521160 countsByYear W20805211602022 @default.
• W2080521160 countsByYear W20805211602023 @default.
• W2080521160 crossrefType "journal-article" @default.
• W2080521160 hasAuthorship W2080521160A5016245381 @default.
• W2080521160 hasAuthorship W2080521160A5033532763 @default.
• W2080521160 hasAuthorship W2080521160A5055691879 @default.
• W2080521160 hasAuthorship W2080521160A5067156920 @default.
• W2080521160 hasAuthorship W2080521160A5077792271 @default.
• W2080521160 hasConcept C126322002 @default.
• W2080521160 hasConcept C167135981 @default.
• W2080521160 hasConcept C195910791 @default.
• W2080521160 hasConcept C2777396551 @default.
• W2080521160 hasConcept C2777637488 @default.
• W2080521160 hasConcept C2778193466 @default.
• W2080521160 hasConcept C2778266534 @default.
• W2080521160 hasConcept C2779631663 @default.
• W2080521160 hasConcept C2779802037 @default.
• W2080521160 hasConcept C2994496256 @default.
• W2080521160 hasConcept C501593827 @default.
• W2080521160 hasConcept C523546767 @default.
• W2080521160 hasConcept C54355233 @default.
• W2080521160 hasConcept C71924100 @default.
• W2080521160 hasConcept C86803240 @default.
• W2080521160 hasConcept C89423630 @default.
• W2080521160 hasConcept C94665300 @default.
• W2080521160 hasConceptScore W2080521160C126322002 @default.
• W2080521160 hasConceptScore W2080521160C167135981 @default.
• W2080521160 hasConceptScore W2080521160C195910791 @default.
• W2080521160 hasConceptScore W2080521160C2777396551 @default.
• W2080521160 hasConceptScore W2080521160C2777637488 @default.
• W2080521160 hasConceptScore W2080521160C2778193466 @default.
• W2080521160 hasConceptScore W2080521160C2778266534 @default.
• W2080521160 hasConceptScore W2080521160C2779631663 @default.
• W2080521160 hasConceptScore W2080521160C2779802037 @default.
• W2080521160 hasConceptScore W2080521160C2994496256 @default.
• W2080521160 hasConceptScore W2080521160C501593827 @default.
• W2080521160 hasConceptScore W2080521160C523546767 @default.
• W2080521160 hasConceptScore W2080521160C54355233 @default.
• W2080521160 hasConceptScore W2080521160C71924100 @default.
• W2080521160 hasConceptScore W2080521160C86803240 @default.
• W2080521160 hasConceptScore W2080521160C89423630 @default.
• W2080521160 hasConceptScore W2080521160C94665300 @default.
• W2080521160 hasIssue "11" @default.

• next